Toxicity and Absorption of Chemicals

Toxicity and Absorption of Chemicals

Key Concepts

• Poor Absorption of Toxicants

  • Low amount absorbed

  • Low rate of absorption

    • Limits/prevents toxicity

Mechanisms Affecting Toxicity (CR)

• Chemical Concentration

  • Insufficient concentration at potential site of action

• Rapid Bio-transformation/Excretion

  • Well-absorbed chemicals

  • Rapid elimination reduces potential for toxicity

  • Decreases concentration at site of action

Conclusion

• Effective absorption and elimination processes can mitigate toxicity.