Chapter 3: Recognition and Response

Immune Antigen and Receptor Molecules

  • BCR, TCR, CD4/CD8

Recetpr-Ligand Binding: occurs via multiple noncovalent bonds

BCR & Antibody

TCR

PAMPs

Cytokines

B-cell Receptor: contains an antibody of defines specificity

T-cell Receptor: specificity is for peptides derived from APC degraded antigen presented on MHC molecules

CD4 & CD8 are T-cell coreceptors that define different subsets of T-cell function