Bacteriophages Notes
Bacteriophages
What are Bacteriophages?
- Bacteriophages, often called phages, are viruses that specifically infect bacteria.
- They are generally considered harmless to humans, animals, and plants.
- Phages exhibit host-specificity, meaning they only infect particular types of bacteria.
- They replicate within a host bacterium.
- The presence of phages suggests the presence of their bacterial hosts.
- Phage detection is a promising strategy for detecting microbial contamination in water due to its sensitivity compared to standard bacterial detection methods.
Discovery of Bacteriophages
- 1896: Ernest Hanbury Hankin reported antibacterial action against cholera in the Ganges and Yamuna rivers in India; this agent could pass through fine porcelain filters.
- 1915: Frederick Twort, a British bacteriologist, discovered an agent capable of infecting and killing bacteria.
- Twort's research was interrupted because of World War I, funding shortage and antibiotic discoveries.
- September 3, 1917: Félix d'Hérelle, a French-Canadian microbiologist working at the Pasteur Institute in Paris, announced the discovery of