VNSG 1500: Unit 1 Integumentary Disorders/Problems
Objective 6: Nursing Assessment of the Skin
A. Health History
B. Physical Assessment
A&P Review of Integumentary System
Skin is the largest organ of the body.
Functions:
1st line of defense against infection
Protects underlying tissues/organs from injury
Receives sensory input from the environment and relays it to the brain
Helps to maintain body temperature
Excretes salt, water, and organic wastes
Protects the body from excessive water loss
Synthesizes Vitamin D
Layers of Human Skin
Epidermis
Dermis
Subcutaneous tissue
Muscle
Epidermal Appendages
Stratum corneum
Sebaceous
Eccrine gland
Capillary loop
Epidermis
Sweat gland
Superficial vascular plexus
Papillary dermis
Reticular dermis
Hair follicle
Apocrine sweat gland
Proximal matrix
Distal matrix
Subcutaneous adipose tissue
Proximal Nail Fold
Cuticle
Nail Bed
Nail Plate
Hyponychium
Distal phalanx
Normal Bacterial Flora of Skin
The number of normal flora differs depending on the location and types of skin.
Relatively moist and shaded skin, such as skin of genital areas, is rich in normal flora.
Types of Normal Bacterial Flora include:
Gram-positive and gram-negative staphylococci
Pseudomonas sp.
Streptococcus sp.
Candida albicans
Risk Factors for Integumentary Disorders
Exposure to chemical and environmental pollutants
Exposure to radiation
Race and age
Exposure to the sun or use of tanning beds
Lack of personal hygiene habits
Use of harsh soaps or other harsh products
Some medications, such as long-term glucocorticoid use
Nutritional deficiencies
Emotional stress
Repeated injury or irritation
Genetic predisposition
Systemic illnesses (Ex.: Diabetes)
Impaired immune system
Assessment of Integumentary System: Health History Questions
When did the rash or lesion first appear?
Can you think of any event or different food you ate or substance you were using just before it appeared?
What is your usual dietary pattern? What do you eat and drink?
Have you noticed if anything makes it worse?
What seems to make it better?
Have you been using any chemicals lately for household cleaning or in pursuit of your hobbies?
Have you been out in rural areas or in the woods lately?
Have you been traveling? Did you visit a tropical area?
Have you had any recent exposure to animals?
What drugs are you taking? Do you take any over-the-counter medications?
Are you using any street drugs? What route of administration?
Have you ever had a drug reaction?
Have you ever had radiation therapy?
Do you have a history of any skin disorders in your family?
Does anyone in the family currently have similar symptoms, such as a rash?
Do you have any allergies?
Are you experiencing itching? Pain? Fever?
Have you had any gastrointestinal problems that began about the same time that the rash or lesion appeared? What about a runny or stuffed-up nose? Cough?
Has the skin condition affected your social life or work?
Physical Assessment of Skin/Hair/Nails
General appearance of skin surface: texture, elasticity, thickness
Condition of areas between skin folds
Type of lesions and distribution, size, and appearance; photograph or measure and document measurements
Appearance of skin adjacent to lesions; note whether reddened areas blanch when mild pressure is applied
Localized or generalized skin edema
Characteristics of secretions: color, viscosity, amount
Odor: description of odor; strong or faint; source—local or generalized
Temperature changes: location of hot spots or cold areas of the skin
Assess for temperature, texture, and moisture of skin by palpating skin
Physical Assessment of Skin/Hair Nails General Tips
Assess skin under good lighting (Don’t do it in the dark!)
Remember to account for differences in the shade of skin: skin lesions/rashes may look different on different skin colors
Pallor in a dark-skinned person presents as an ashen-gray tone to the skin. In a brown-skinned person, pallor gives the skin a yellow-brown color.
Jaundice is best assessed in dark-skinned people by looking at the sclera of the eye
Older adults will have normal variations from younger people
Skin turgor is assessed by lifting a fold of skin on the forearm, chest, or abdomen between two fingers and seeing how fast it falls back into place. Skin that takes longer than 1 to 2 seconds to return to place is called “poor skin turgor” and indicates dehydration.
When checking the temperature of the skin, the back of the hand should be used.
Types of Lesions: Macule/Patch
Nonpalpable (can’t be felt by touch), flat area with a change in skin color
Macule = <1 cm in diameter
Patch = >1 cm in diameter
Examples:
Freckles: Small, flat, circular spots that appear on skin exposed to the sun, resulting from increased melanin production.
Petechiae: Tiny, circular, non-raised patches that appear on the skin or in mucous membranes as a result of localized hemorrhage.
Measles: A highly contagious viral disease characterized by a distinct red, flat rash that starts on the face and spreads to the rest of the body.
Flat mole (nevus): A common skin growth that is typically flat or slightly raised, with a consistent color ranging from brown to black.
Types of Lesions: Papule/Plaque
Elevated, palpable (can be felt by touch), solid mass
Papule = <0.5 cm in diameter
Plaque = >0.5 cm in diameter
Papule Examples:
Warts: Small, benign growths on the skin caused by the human papillomavirus (HPV).
Moles (Nevi): Common skin growths composed of clusters of melanocytes; can be flat or raised, and vary in color.
Lipoma: A benign tumor composed of fatty tissue, typically soft and movable beneath the skin.
Basal Cell Carcinoma: A common type of skin cancer that appears as a small, waxy bump or flat, flesh-colored or brown lesion.
Plaque Examples:
Psoriasis: A chronic autoimmune skin condition characterized by raised, red, scaly patches. Common on elbows, knees, and scalp.
Actinic Keratosis: A rough, scaly patch on the skin that develops from years of sun exposure. It is considered precancerous and can lead to squamous cell carcinoma.
Types of Lesions: Vesicle (blister)/Bulla
Circumscribed, elevated, palpable mass containing serous fluid
Vesicle = <0.5 cm diameter
Bulla = >0.5 cm diameter
Examples: Varicella, Herpes Zoster, 2nd degree burns, Poison Ivy
Types of Lesions: Wheal
Firm, edematous, irregularly shaped area; diameter variable
Examples: Hives, mosquito bites
Types of Lesions: Pustule
Elevated, superficial lesion filled with purulent fluid
Examples: Acne, impetigo
Objective 7: Common Diagnostic Studies for Skin Disorders
A. Skin Biopsy
B. Patch Testing
C. Skin Scrapings
D. Tzanck Smear
E. Wood Light
F. Clinical Photographs
G. Wound Culture
Diagnostic Tests: Skin Biopsy
Collection of a small piece of skin tissue for histopathologic study
Methods include punch, excision, and shave
Pre-procedure nursing interventions: verify consent has been obtained, cleanse site as ordered
Post-procedure nursing interventions:
Put dressing on biopsy site
Monitor biopsy site for bleeding/infection
Educate patient to keep dressing dry and in place for at least 8 hours and to clean the area daily and use antibiotic ointment as prescribed
Educate patient about s/s of infection to watch for
Diagnostic Tests: Patch Testing
Used for allergy testing
Patient wears patches over allergens for 48 hours, and then skin is assessed after 72 hours
Reaction of skin to allergens indicates allergy to the substance
Weak positive: redness, fine elevation, or itching
Moderate positive: fine blisters, papules, severe itching
Strong positive: blisters, pain, and ulceration
Diagnostic Tests: Skin Scrapings
Used to test suspected fungal lesions
Scalpel blade moistened with oil to collect skin scrapings
Skin scraping is then examined under a microscope for spores
Scabies can also be visualized this way
Diagnostic Tests: Tzanck Smear
Used to examine skin cells from blistering skin conditions (Herpes)
Collects secretions from blisters, apply to glass slide, stain, and view with microscope
Diagnostic Tests: Wood Light Exam
Special ultraviolet light
Can be used to detect some bacterial or fungal skin infections
Can also detect skin pigment disorders such as vitiligo (skin devoid of melanin will increase in whiteness with UV light)
Diagnostic Tests: Clinical Photographs
Used to document wound assessment and progress resulting from the treatment of wound
May also be used to track suspicious moles that are changing
Diagnostic Tests: Skin/Wound Cultures
Use of a sterile applicator and appropriate culture tube to collect a small sample of skin or wound culture
Once the organism has been cultured, colonies can be tested for sensitivity to certain antiinfective agents
Always obtain skin/wound culture samples before instituting antibiotic therapy
Objective 8: Common Therapeutic Management of Skin Care and Wounds
A. Skin Care
B. Wound Care & Dressings
Surgical Wound Care
Drain Care
Dehiscence/Evisceration
Skin Care
Protecting the skin: maintain acidic pH of skin, help maintain skin’s moisture
Use mild soaps
Avoid deodorant soaps and laundry detergents
Consider all skin lesions as potentially infectious; use gloves when providing wound care
Wound Care Types of Dressings
Passive: protect wound and maintain a moist environment (Tegaderm)
Interactive: can absorb some drainage and maintain the moisture of the wound bed while keeping peri-wound skin dry (Hydrocolloids, alginates, hydrogels)
Active: improve the healing process and decrease healing time (Skin grafts)
Wicker: used with sinus tracts or undermining, absorb drainage
Filler: used for deep wounds
Cover: may be used for superficial wounds or as a secondary dressing over deep wounds
Wound Care: Autolytic Debridement
Uses body’s own enzymes to break down necrotic tissues on the wound bed so that the wound can heal
Must use an occlusive dressing that will keep the wound moist
May produce a foul odor as dead tissue breaks down
Assessing for Wound Infection
Symptoms and Signs
ACUTE WOUNDS
Localized infection
Classical findings:
New or increasing pain
Erythema
Local warmth
Swelling
Purulent discharge
Delayed healing
Abscess
Spreading infection
As for localized infection PLUS:
Extension of erythema
Lymphangitis
Crepitus in soft tissues
Wound breakdown/dehiscence
Malodour
Things That Delay Wound Healing
Poor circulation
Poor nutrition: not enough protein in diet, patient may have low lab values for Prealbumin and Albumin
Poorly controlled Diabetes Mellitus
Wound Infection
Promoting Wound Healing
Prevent infection: adhere to good hand hygiene, practice clean/sterile technique during dressing changes
Tight blood sugar control for diabetics
Promote good circulation to the wound
Teach patient to eat protein and Vitamin C
Surgical Wound Care: Assess for
Approximation of wound edges
Integrity of sutures or staples
Redness, warmth, swelling, unusual tenderness, discharge
Assess skin around wound for reaction to tape or other adhesives
Dehiscence vs. Evisceration
Can result from too much strain placed on the wound:
Trapped fluid building up inside the wound (hematoma or infection)
Patient moving too vigorously or coughing
Obesity
Poor skin integrity due to age, nutrition, corticosteroid use
Most likely to occur with abdominal wounds
Patient may state they felt a popping sensation or something giving way. There may be a gush or serosanguinous fluid.
Nursing Priorities:
Assess for protrusion of intestines or other abdominal viscera
Place patient in Low Fowler’s position and instruct to lie still
Cover any protruding organs with sterile saline dressing
Notify the surgeon immediately
JACKSON-PRATT DRAIN CARE
(Information regarding drain care)
Objective 9: Pressure Injuries
A. Pathophysiology
B. Prevention
C. Assessment and Staging
D. Nursing Management/Treatment
Pressure Ulcers: Pathophysiology
Caused by sustained pressure, friction, or shear on the skin, which limits the blood flow.
Restricted blood flow causes cell injury and death.
Risk Factors:
Bedrest
Immobility
Inadequate subcutaneous tissue
Poor nutrition
Incontinence
Poor circulation
Advanced age
DM, PVD, Stroke, Obesity, Cognitive Impairment
Pain meds and sedatives
Smoking
Progression of a Pressure Ulcer
Grade 1: Non-blanchable erythema (redness) of intact skin. Discoloration of the skin, warmth, oedema, induration, or hardness may also be used as indicators, particularly on individuals with darker skin
Grade 2: Partial thickness skin loss involving epidermis, dermis, or both. The ulcer is superficial and presents clinically as an abrasion or blister
Grade 3: Full thickness skin loss involving damage to or necrosis of subcutaneous tissue that may extend down to, but not through underlying fascia
Grade 4: Extensive destruction, tissue necrosis, or damage to muscle, bone, or supporting structures with or without full thickness skin loss
Pressure Ulcers
Suspected Deep Tissue Injury: intact skin with a purple or maroon discoloration. Tissue may be firm, boggy, painful, cool, or warm
Unstageable Pressure Ulcer: Wound bed is covered with eschar or slough that obscures the depth of the wound
Pressure Ulcers: Treatment
Debridement: removal of eschar or slough
Wound care: dressings should keep wound bed moist
Measurement: should be measured and documented when first discovered and at least once a week after that
Negative pressure wound therapy
Hyperbaric oxygen therapy
Increase protein intake to promote healing
Pressure Ulcers: Prevention
Thorough skin assessment and good skin care
Reposition every 2 hours
Use positioning devices and padding
Special mattresses/air beds
HOB a lowest degree possible for patients on bedrest
Use draw sheet or lifting device to move patient in bed
Keep skin clean and dry
Don’t massage bony prominences
Good nutrition
Objective 10: Nursing Management of Pruritus
A. Pathophysiology
B. Medical Management
C. Nursing Management
D. Gerontologic Considerations
Pruritus, aka “Itching”
Pathophysiology: scratching pruritus areas causes histamine to be released, which produces more pruritus
Pruritus tends to worsen at night
The underlying cause of itching could be several things: allergies, dry skin, cholestasis, or uremia
Gerontologic Consideration: pruritus occurs more frequently in older adults as a result of dry skin. They are also more likely to have a systemic illness that causes pruritus.
Pruritus, aka “Itching”: Medical Management
Topical creams containing Lidocaine or Prilocaine
Topical corticosteroids
Oral antihistamines: Diphenhydramine, Hydroxyzine
SSRIs (Fluoxetine, Sertraline) for cholestatic itching or uremic itching
Skin moisturizers
Lotions that contain menthol or camphor
Oral Antihistamines
Diphenhydramine (Benedryl), Hydroxyzine (Atarax), Cetirizine (Zyrtec)
Side Effects: Drowsiness, Dry Mouth, Dizziness
Teaching: take at bedtime to avoid daytime drowsiness
Pruritus, aka “Itching”: Nursing Management
Teach patient to take tepid bath rather than hot
Don’t rub with towel, but blot dry
Use emollient lotion after baths to trap moisture
Avoid situations that cause vasodilation: overheating, alcohol intake, hot/spicy foods
Use a humidifier if the cause of itching is dry skin
Avoid synthetic materials that may irritate skin
Keep nails trimmed short to avoid breaking skin
Objective 11: Common Skin Disorders/Infections
A. Secretory Disorders
Acne Vulgaris
Acne Rosacea
B. Infections Skin Disorders
Bacterial: Impetigo, Folliculitis/Furuncles/Carbuncles
Viral: Herpes Zoster
Fungal: Yeast, Tinea (Ringworm)
Parasitic: Pediculosis & Scabies
C. Non-infectious Skin Disorders
Contact dermatitis
Psoriasis
Blistering Diseases
TEN & Stevens-Johnson Syndrome
Skin Disorders/Problems: Secretory Disorders
Acne Vulgaris
Acne Rosacea
Acne
Acne is a disorder of the skin characterized by papules and pustules over the face, back, and shoulders.
Two Types: Acne Vulgaris and Acne Rosacea
Acne Vulgaris: Etiology
The exact cause is unknown but may include hormonal influences on the sebaceous glands, increased sebum production, and proliferation of the enzymes that reduce lipids to irritating fatty acids
Acne Vulgaris: Medical Diagnosis/Management
Diagnosis by examination and history
Topical Treatments:
Retinoic Acid (Retin-A) topical
Benzoyl peroxide
Antibiotics: Tetracycline, Erythromycin
Oral contraceptives
Isotretinoin (used to be Accutane) for severe cystic acne (SERIOUS SIDE EFFECTS ASSOCIATED WITH THIS DRUG)
Mandatory effective contraception while on this drug and up to 8 weeks afterward (teratogenic effects)
Avoid Vitamin A supplements while on this drug
The most common side effect is cheilitis (inflammation of the lips)
Acne Vulgaris: Nursing Management
Wash face gently with mild soap. Scrubbing and harsh soaps increase inflammation
Avoid squeezing pimples
Try to keep hands off face as much as possible
Give support to teens dealing with body image issues due to acne
Acne Rosacea: Etiology and Risk Factors
Etiology: Cause is not really known
S/S: Facial redness, pimples, dilation of capillaries on face (“spider veins”)
Risk Factors:
Age: usually develops between 30-60 years of age
Gender: more common in women than men
Fair Skin
Ethnicity: Northern or Eastern European heritage
Sun Exposure
Hx of Acne Vulgaris
Acne Rosacea: Medical Diagnosis/Management
Diagnosis by examination and history
Topical Treatments: Metronidazole cream
Avoidance of triggers: sun exposure, caffeine, alcohol, stress, spicy foods
Nursing Management
Treatment will most likely be lifelong
How to apply topical medication
Use gentle soaps, fragrance- free skincare/make-up products
Use sunscreen with SPF of 15 or higher
Skin Disorders/Problems: Bacterial
Impetigo
Folliculitus/Furuncles/Carbuncles
Impetigo
Superficial skin infection caused by Staph, Strep, or multiple bacteria, tends to occur in skin that has been cut, scraped, or has some other small opening
Clinical manifestations:
Small red macules that turn into vesicles that rupture and crust over
Lesions usually found on the face and extremities
Crusts are a yellowish color and easily removed
Impetigo: Medical Management
Medical Management:
Topical antibiotics: Mupirocin
Lesions must be washed and crusts removed before applying antibiotic ointment (gloves should be worn)
Systemic antibiotics may be used if widespread or when fever is present
Nursing Management:
Bathe patient daily with bactericidal soap
Practice good hygiene to avoid spread, don’t share linens
Avoid contact with other people or keep lesions covered if possible until lesions heal
Bacterial Skin Infections
Cellulitis: an infection of the dermis and subcutaneous tissue, usually caused by Staphylococcus. Area is red, swollen, and painful
Folliculitis/Furuncles (boils): inflammations of hair follicles. Lesion may contain pus and necrotic tissue.
Carbuncles: a collection of faruncles (boils).
Treated with systemic antibiotics
May use astringent solutions such as Burow solution to help draw out pus
May perform Incision & Drainage of the abscess with debridement of any necrotic tissue
Skin Disorders/Problems: Viral Skin Infections
Herpes Zoster (Shingles)
Viral Skin Infections: Herpes Zoster (Shingles)
Reactivation of dormant varicella vaccine by trauma, malignancy, stress, or local radiation
More common in older adults
Preventable with vaccination: Shingrix vaccine recommended for immunocompetent adults age 50 and over
If a person has never had chicken pox or varicella vaccine, they cannot get shingles.
Signs/Symptoms:
Fatigue, low-grade fever
Aching along nerve pathway (dermatome) with or without redness
3-5 days after onset, small groups of vesicles appear on the skin following the nerve pathway
Eventually, vesicles change to painful scaly lesions that itch
Pain may persist after healing of lesions, and the patient may develop postherpetic neuralgia that lasts for years
Viral Skin Infections: Herpes Zoster (Shingles) Medical Diagnosis/Management
Diagnosis by examination and history
Treatment: no cure, the purpose is to shorten the course of illness and manage pain
Antivirals: Topical and oral Zovirax (acyclovir), Valacyclovir (Valtrex), or Famciclovir (Famvir)
Analgesics
Gabapentin (Neurontin)
Corticosteroids may be used to reduce inflammation
Earlier the condition is treated, the better the chances to decrease the amount & duration of pain
Nursing Management
Teach about medications
Treat pain and itching: cold compresses, Calamine lotion, distraction techniques
Monitor for secondary bacterial infection
Don’t wait until diagnosis to institute airborne and contact precautions if suspect patient has shingles
Patient should be isolated until all lesions have crusted
If lesions are localized and can be covered with a dressing and the patient is not immunocompromised, standard precautions are sufficient
Skin Disorders/Problems: Fungal Skin Infections
Yeast
Tinea
Fungal Skin Infections
2 Types of fungal infections in humans:
Fungi that are truly pathogenic in humans (very few)
Fungi that are opportunistic and require host to be immunocompromised
S/S: itching, swelling, breakdown of tissues, tend to develop in warm, moist areas.
Examples: Candidiasis (yeast), Tinea pedis (Athlete’s foot)
Remember that diabetics are at greater risk for fungal skin infections
Tinea: “Ringworm”
Fungal infection of the skin, not a worm
Contagious: affected children should not share grooming items, headgear, or clothing with other children
Can me transmitted from animals such as household pets
Gymnasium mats and helmets are another source of infection
Treatment: Antifungal ointment, oral antifungals if a problem is widespread or persistent
Fungal Skin Infections: Tinea Pedis (Athlete’s Foot) Medical Diagnosis/Management
Diagnosis by examination
Treatment:
Topical Antifungals: Miconazole, Clotrimazole, Ketoconazole
Keep the area dry, clean, and exposed to air and sunlight as much as possible
Clean cotton socks, separate toes with gauze or cotton.
Systemic antifungal such as Terbinafine (Lamisil) for persistent infections
Nursing Management
Teach patient to keep feet clean and dry
Wear clean cotton socks every day
How to apply topical med
Disinfect tub/shower after bathing to prevent transmission to others
Use own towel
Always wear shoes at pool/gym/locker rooms
Monitor liver function of patients on oral antifungals
Skin Disorders/Problems: Parasitic Skin Infections
Pediculosis Capitis (Lice)
Scabies
Scabies
A skin infestation caused by the scabies mite
Lesions are created as a female scabies mite burrows into the epidermis and deposits eggs & feces.
Inflammatory response causes intense itching
Maculopapular lesions, denser distribution in folds and creases
Transmitted via prolonged contact
Can affect people regardless of age, sex, personal hygiene, or socioeconomic status
Treatment: Scabicide such as Elimite (Permethin 5%) cream, oral Ivermectin
Contact precautions
Pediculosis Capitis (Head Lice)
Infestation of the scalp by Pediculosis humanus capitis, a tiny bloodsucking insect
Anyone can get head lice no matter age, socioeconomic level, or cleanliness
The female louse lays eggs at night on the hair shaft close to the skin; nits (eggs) hatch in 7-10 days
Itching is caused by crawling of insects and insect saliva on the skin
Signs/Symptoms: itching of the scalp, especially behind ears and at the nape of the neck; visualization of insect or nit
Treatment: Pediculicides such as permethrin 1% shampoo and manual removal of nits with a fine-toothed comb; should retreat in 7-10 days in case some nits were missed
Lice do not jump or fly, but they can be transmitted through prolonged contact or sharing of combs, hats, hair ornaments
Identifying Head Lice
(Includes images of lice and nits)
Skin Disorders/Problems: Non-infectious Skin Disorders
Contact Dermatitis
Psoriasis
Dermatitis: Contact Dermatitis
Contact Dermatitis: allergic response to a substance on the skin
Redness, swelling, pruritis, and vesicular lesions
Examples: poison ivy, poison oak, certain soaps, latex allergy
Atopic Dermatitis (Eczema): autoimmune
More common in infancy/childhood
Stasis Dermatitis: usually occurs on LE as a result of venous stasis & edema
Seborrheic dermatitis (cradle cap): Lesions appear as scaly white or yellowish plaques with mild pruritus.
Dermatitis: Diagnosis/Treatment
Diagnosed by inspection and history
Treatment:
Avoidance of irritants or allergens
Skin moisturization
Control of inflammation/itching with topical or oral corticosteroids
Nursing Management
Teach patient to avoid allergens/irritants
Teach how to use topical meds
Take tepid rather than hot baths to decrease itching
Caution patients to avoid becoming overheated and not to puncture vesicles
Pat skin dry rather than rub
Psoriasis
Psoriasis is a chronic autoimmune skin disease that speeds up the growth cycle of skin cells, causing an overgrowth of skin cells.
Etiology: Genetic factors, Autoimmune
S/S:
Red patches with thick, silvery scales which may range from a few spots to large areas of scaly patches
Small scaling spots, commonly noted in children
Dry, cracked skin which may be accompanied by bleeding
Itching, burning, and painful lesions which may be accompanied by soreness
Thick, pitted, or ridged nails
Swollen joints with stiffness
NO CURE, lifelong problem
Has episodes of exacerbation and remission
Risk Factors: Someone in family with psoriasis
Psoriasis: Medical Diagnosis/Management
Diagnosis by examination and history, rule out other skin disorders
Mild-Moderate Cases:
Steroid creams such as Triamcinolone and sunlight in moderate doses
Coal Tar soaps
Artificial UV ray therapy
Severe Cases:
Antiproliferatives: Methotrexate
Biologics: Humira, Remicade, Embrel
Monoclonal Antibody: Siliq
Nursing Management
Skin must be kept moisturized: use moisturizer prescribed by dermatologist and air humidifiers
Prevent injury to skin, because small cuts and scrapes can cause the development of plaques
Some medications such as antiproliferatives and biologics are immunosuppressant, avoiding infection is really important
Skin Disorders/Problems: Blistering Skin Disorders
Toxic Epidermal Necrolysis (TEN)
Stevens-Johnson Syndrome (SJS)
TEN & SJS
Allergic reaction with skin manifestations. It can be caused by an infection, malignancy, or medication or be categorized as idiopathic. Medications that cause the condition include: Antibiotics (esp. Sulfa), Anticonvulsants, NSAIDS, allopurinol, and Meloxicam. TEN is a more severe form of SJS
Risk Factors: Someone in family who has had SJS, Female, Older adults
TEN & SJS: S/S
The early symptoms of Stevens-Johnson syndrome resemble that of flu and include fever, sore mouth or throat, tiredness, cough, and burning sensation in the eyes. As the condition advances, the symptoms include:
Unexplained skin pain
Painful red or purplish rash
Spreading of rashes
Blister formation on the skin and mucous membranes of the mouth, nose, eyes, and genitals
Dying of the affected skin
Shedding and healing of the dead skin
Facial swelling
Swollen lips covered in crusty sores
Complications: Keratoconjunctivitis, sepsis, multiple organ dysfunction syndrome
TEN & SJS: Management
Good, thorough skin assessment daily
Review medications to identify possible cause (Remember OTC meds can cause SJS too!)
Discontinue medication thought to be causing the condition
Supportive IV fluids and nutrition care (may be TPN)
Aseptic wound care to avoid infection, possibly in burn center
Analgesics for pain
Sometimes corticosteroids are still used, but this is controversial due to immunosuppression caused
Objective 12: Skin Growths and Skin Cancer
Benign Skin Tumors
Cysts
Seborrheic & Actinic Keratoses
Verrucae: Warts
Angiomas
Pigmented Nevi: Moles
Keloid Scars
Malignant Skin Tumors
Basal cell and squamous cell carcinoma
Melanoma
Benign Skin Tumors
Cysts: may contain fluid or solid material, may be surgically removed
Seborrheic Keratoses:
Wartlike lesions, range in color from tan to black
Usually located on the face, shoulders, chest, and back
Should be assessed periodically for changes that suggest malignancy
Actinic Keratoses
Actinic keratoses are considered premalignant (rough and scaly)
May transform into squamous cell carcinoma
Benign Skin Tumors
Verrucae: Warts, caused by infection with the human papillomavirus
Considered benign unless in the genital area: genital warts can be precancerous
Contagious and can be spread from skin-to-skin contact
Usually not painful unless on the soles of the feet
May be removed with topical agents (salicylic acid) or frozen/burned off by a dermatologist
Benign Skin Tumors
Angiomas: vascular tumors, appear as flat red patches (port-wine angiomas) or raised, bright red nodular lesions (