Cognition

Alteration in Cognition

Normal Cognition

  • Definition: Cognition is defined as the ability to think, learn, remember, and make decisions.

Types of Cognitive Alterations

  • Cognitive alterations can be categorized into two primary types: delirium and dementia.

Dementia
  • Definition: Dementia is characterized by a chronic and gradual decline in cognitive function.

  • Key characteristics:

    • Progressive nature (function worsens over time)

    • Irreversible in most cases

Common Symptoms of Dementia
  • Memory loss

  • Confusion

  • Impaired judgment

  • Personality changes

  • Difficulty performing daily activities

Types of Dementia

  1. Alzheimer's Disease

    • Cause: Characterized by the build-up of amyloid plaques and neurofibrillary tangles. This leads to brain cell death, making it the most common form of dementia.

    • Early Symptoms:

      • Short-term memory loss

      • Difficulty learning new information

    • Later Symptoms:

      • Severe memory loss

      • Disorientation (e.g., inability to recognize family members)

    • Unique symptoms include visual hallucinations and fluctuations in cognitive abilities.

    • Physical symptoms may include tremors, stiffness, and slow movement.

  2. Lewy Body Dementia

    • Caused by Lewy body protein deposits in the brain.

    • Similar to Alzheimer's but often includes visual hallucinations.

  3. Vascular Dementia

    • Cause: Results from reduced blood flow to the brain, often following strokes or multiple small infarcts.

    • Symptoms:

      • Symptoms may appear suddenly rather than gradually.

    • Risk Factors:

      • Hypertension

      • Diabetes

      • Smoking

  4. Frontotemporal Dementia

    • Main Areas Affected: Damage primarily occurs in the temporal lobes.

    • Main Changes:

      • Memory impairment

      • Personality changes

      • Impulsive behavior

      • Loss of social awareness

    • Notably, memory loss is not usually the first symptom.

Delirium

  • Definition: Delirium is defined as an acute state characterized by confusion.

Key Features of Delirium
  • Onset: Sudden, often related to a fluctuating state of consciousness.

  • Generally reversible symptoms that arise due to another medical problem.

Common Causes of Delirium
  1. Infection

  2. Medications

  3. Dehydration

  4. Electrolyte imbalance

  5. Hypoxia

  6. Surgery

  7. Pain

Symptoms of Delirium
  • Sudden confusion

  • Difficulty with concentration

  • Disorganized thinking

  • Agitation or restlessness

  • Altered levels of consciousness

  • Symptoms may fluctuate throughout the day.

At-Risk Populations
  • Older adults are identified as being at very high risk for developing delirium.