Final Review- Bio121

Chapter 1: Themes of Biology

  • Anabolism: Chemical reactions that build large molecules from small ones.

  • Catabolism: Breakdown of complex molecules into simpler ones, releasing energy.

Chapter 2: Chemistry and Atomic Structure

  • Atomic Number: Number of protons in an atom.

  • Atomic Mass: Total number of protons and neutrons.

  • Isotopes: Atoms with the same number of protons but different numbers of neutrons.

  • Valence Electrons: Electrons in the outermost shell.

  • Ionic Bond: Transfer of electrons between atoms.

  • Covalent Bond: Sharing of electrons between atoms.

  • Cation: Positively charged (loses an electron).

  • Anion: Negatively charged (gains an electron).

  • Water: Polar bond due to unequal sharing of electrons. Cohesion allows for surface tension and water transport in plants. Ice floats as it is less dense than water.

  • Dehydration Synthesis: Bonds monomers by losing water; Hydrolysis reverses this process.

  • Carbon: Can form diverse large molecules due to its 4 valence electrons.

  • Hydrogen Bonds: Weak attractions between polar molecules.

  • Structural Isomers: Different arrangements of atoms.

  • Cis-Trans Isomers: Geometric variations around double bonds.

  • Ester Bond: Connects fatty acids to glycerol in triglycerides.

  • Glycosidic Bond: Connects sugars and starches.

Chapter 3: Cells as Units of Life

  • Cell Types:

    • Prokaryotic Cells: Lack a nucleus (e.g., bacteria).

    • Eukaryotic Cells: Contain a nucleus (e.g., plants, animals).

  • Endomembrane System: Includes nucleus, ER, Golgi apparatus, lysosomes, vesicles for protein and lipid synthesis and transport.

  • Energy Organelles:

    • Mitochondria: Convert food's chemical energy into ATP.

    • Chloroplasts: Perform photosynthesis, converting solar energy into stored chemical energy.

    • Both evolved by endosymbiosis—originally from prokaryotic cells.

  • Cytoskeleton: Network of protein fibers supporting cell shape, facilitating movement, and guiding transport.

Chapter 4: Membranes and Transport

  • Plasma Membrane: Lipid bilayer with embedded proteins controlling cell entry and exit.

  • Transport Processes:

    • Passive Transport: No energy needed (e.g., diffusion, osmosis).

    • Active Transport: Requires energy.

  • Cell Junctions: Enable adherence, communication, and resource sharing (tight junctions, gap junctions, desmosomes).

Chapter 5: Energy Transformations and Metabolism

  • Energy Types:

    • Kinetic Energy: Energy of motion.

    • Potential Energy: Stored energy in structures, including chemical energy.

  • Laws of Thermodynamics:

    • Energy cannot be created or destroyed; it changes form, increasing entropy.

  • Chemical Reactions:

    • Exergonic: Release energy.

    • Endergonic: Require energy, producing high-potential energy products.

  • ATP: Powers cellular work by coupling exergonic and endergonic reactions.

Chapter 6: Cellular Respiration

  • Photosynthesis: Converts solar energy to organic molecules and O2 from CO2 and H2O.

  • Cellular Respiration: Uses O2 to break down organic molecules, producing CO2 and H2O, releasing energy stored in ATP.

    • Glycolysis: Breakdown of glucose to pyruvate; yields 2 ATP and 2 NADH.

    • Citric Acid Cycle: Processes pyruvate, producing NADH and FADH2, and releasing CO2.

    • Oxidative Phosphorylation: Most ATP produced via electron transport chain and chemiosmosis.

Chapter 7: Photosynthesis

  • Occurs in chloroplasts with light reactions (ATP and NADPH production) and Calvin Cycle (sugar synthesis).

  • Photophosphorylation: H+ gradient drives ATP synthesis.

Chapter 8: Cell Division and Genetics

  • Cell division influenced by growth factors; regulated by a cell cycle control system.

  • Cancer: Uncontrolled cell division leading to tumors.

  • Chromosomes: Organizing genetic information; duplicated before division.

Chapter 9: Mendelian Genetics

  • Mendel’s Laws: Describe inheritance patterns and segregation of alleles.

  • Sex-linked Inheritance: X-linked genes often affect males more due to recessive nature.

Chapter 10: Molecular Genetics

  • Bacterial Transformation: Griffith's experiment showed DNA can change bacterial traits.

  • DNA Structure: Watson and Crick’s model based on Franklin's work, leading to understanding DNA's role in heredity.

Chapter 11: Gene Expression

  • Prokaryote vs. Eukaryote: Differences in transcription and translation locations and processes.

  • Operons and Regulatory Proteins: Control gene expression in bacteria.

Chapter 12: Biotechnology

  • Transformation and Transduction: Mechanisms of DNA transfer in bacteria.

  • Restriction Enzymes: Cut DNA at specific sequences for genetic engineering.

  • PCR and Gel Electrophoresis: Techniques for DNA analysis and profiling.