Final Review- Bio121
Chapter 1: Themes of Biology
Anabolism: Chemical reactions that build large molecules from small ones.
Catabolism: Breakdown of complex molecules into simpler ones, releasing energy.
Chapter 2: Chemistry and Atomic Structure
Atomic Number: Number of protons in an atom.
Atomic Mass: Total number of protons and neutrons.
Isotopes: Atoms with the same number of protons but different numbers of neutrons.
Valence Electrons: Electrons in the outermost shell.
Ionic Bond: Transfer of electrons between atoms.
Covalent Bond: Sharing of electrons between atoms.
Cation: Positively charged (loses an electron).
Anion: Negatively charged (gains an electron).
Water: Polar bond due to unequal sharing of electrons. Cohesion allows for surface tension and water transport in plants. Ice floats as it is less dense than water.
Dehydration Synthesis: Bonds monomers by losing water; Hydrolysis reverses this process.
Carbon: Can form diverse large molecules due to its 4 valence electrons.
Hydrogen Bonds: Weak attractions between polar molecules.
Structural Isomers: Different arrangements of atoms.
Cis-Trans Isomers: Geometric variations around double bonds.
Ester Bond: Connects fatty acids to glycerol in triglycerides.
Glycosidic Bond: Connects sugars and starches.
Chapter 3: Cells as Units of Life
Cell Types:
Prokaryotic Cells: Lack a nucleus (e.g., bacteria).
Eukaryotic Cells: Contain a nucleus (e.g., plants, animals).
Endomembrane System: Includes nucleus, ER, Golgi apparatus, lysosomes, vesicles for protein and lipid synthesis and transport.
Energy Organelles:
Mitochondria: Convert food's chemical energy into ATP.
Chloroplasts: Perform photosynthesis, converting solar energy into stored chemical energy.
Both evolved by endosymbiosis—originally from prokaryotic cells.
Cytoskeleton: Network of protein fibers supporting cell shape, facilitating movement, and guiding transport.
Chapter 4: Membranes and Transport
Plasma Membrane: Lipid bilayer with embedded proteins controlling cell entry and exit.
Transport Processes:
Passive Transport: No energy needed (e.g., diffusion, osmosis).
Active Transport: Requires energy.
Cell Junctions: Enable adherence, communication, and resource sharing (tight junctions, gap junctions, desmosomes).
Chapter 5: Energy Transformations and Metabolism
Energy Types:
Kinetic Energy: Energy of motion.
Potential Energy: Stored energy in structures, including chemical energy.
Laws of Thermodynamics:
Energy cannot be created or destroyed; it changes form, increasing entropy.
Chemical Reactions:
Exergonic: Release energy.
Endergonic: Require energy, producing high-potential energy products.
ATP: Powers cellular work by coupling exergonic and endergonic reactions.
Chapter 6: Cellular Respiration
Photosynthesis: Converts solar energy to organic molecules and O2 from CO2 and H2O.
Cellular Respiration: Uses O2 to break down organic molecules, producing CO2 and H2O, releasing energy stored in ATP.
Glycolysis: Breakdown of glucose to pyruvate; yields 2 ATP and 2 NADH.
Citric Acid Cycle: Processes pyruvate, producing NADH and FADH2, and releasing CO2.
Oxidative Phosphorylation: Most ATP produced via electron transport chain and chemiosmosis.
Chapter 7: Photosynthesis
Occurs in chloroplasts with light reactions (ATP and NADPH production) and Calvin Cycle (sugar synthesis).
Photophosphorylation: H+ gradient drives ATP synthesis.
Chapter 8: Cell Division and Genetics
Cell division influenced by growth factors; regulated by a cell cycle control system.
Cancer: Uncontrolled cell division leading to tumors.
Chromosomes: Organizing genetic information; duplicated before division.
Chapter 9: Mendelian Genetics
Mendel’s Laws: Describe inheritance patterns and segregation of alleles.
Sex-linked Inheritance: X-linked genes often affect males more due to recessive nature.
Chapter 10: Molecular Genetics
Bacterial Transformation: Griffith's experiment showed DNA can change bacterial traits.
DNA Structure: Watson and Crick’s model based on Franklin's work, leading to understanding DNA's role in heredity.
Chapter 11: Gene Expression
Prokaryote vs. Eukaryote: Differences in transcription and translation locations and processes.
Operons and Regulatory Proteins: Control gene expression in bacteria.
Chapter 12: Biotechnology
Transformation and Transduction: Mechanisms of DNA transfer in bacteria.
Restriction Enzymes: Cut DNA at specific sequences for genetic engineering.
PCR and Gel Electrophoresis: Techniques for DNA analysis and profiling.