WEEK 7 CROSS-SECTIONAL & COHORT STUDY
Observational Studies
- Definition: Researchers observe subjects in their natural environment without intervention.
- Types: Includes cohort studies, case-control studies, and cross-sectional studies.
- Key Point: They can suggest correlations but do not establish definitive cause-and-effect relationships.
Experimental Studies
- Definition: Researchers conduct controlled tests where they manipulate one or more variables.
- Goal: Aim to establish a cause-and-effect relationship between variables.
- Key Point: Variables are controlled to isolate effects and determine causal relationships.
Differences Between Observational and Experimental Studies
- Observational Studies: No manipulation of variables; record occurrences naturally.
- Experimental Studies: Involves manipulation of variables to test outcomes.
Cross-Sectional Studies
- Definition: Captures data at a single point in time among participants.
- Purpose: Often used to assess prevalence of a condition or disease in a population.
- Nature: Descriptive and can identify associations but cannot establish causality.
- Example: Comparing prevalence of stress levels based on seating position in a classroom.
- Limitations: No follow-up or temporality, hence limited in drawing causal conclusions.
Cohort Studies
- Definition: Follows a group of people over time to assess changes and outcomes.
- Nature: Data can be recorded prospectively (future) or retrospectively (past).
- Purpose: Useful for studying incidence and causes of diseases.
- Causality: It can provide evidence for causality as exposure is recorded before outcomes.
- Example: Investigating health outcomes in individuals with different exposure statuses (e.g., comorbid health conditions).
Hierarchy of Evidence in Research
- Clinical Interventions: RCTs (Randomized Controlled Trials) are rated highest.
- Cohort Studies: Represent significant evidence for prognosis and causality, placed just below RCTs.
- Importance: Understanding the evidence hierarchy is essential for program/policy applications.
Conducting a Cross-Sectional Study - Example
- Research Question: Are people at the front of a classroom more stressed than those at the back?
- Null Hypothesis: No significant difference in perceived stress levels based on seating position.
- H0: No difference between perceived stress of students sitting at the front and back.
- Methodology: Use a stress assessment tool (e.g., Stress-o-meter) to measure stress levels.
- Statistical Analysis: Use t-tests to compare means of two groups (front vs. back).
Potential Biases in Cross-Sectional Studies
- Validity/Reliability: Stress measures may lack established validity.
- Self-Report Limitations: Issues such as recall bias or social desirability factor into results.
- Temporality: Cross-sectional studies represent one point in time; cannot infer causality.