A&P II - Cardiovascular (Unit 2) Lecture

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Pulmonary Circuit

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Pulmonary Circuit

Blood flow to the heart then to the lungs then back to heart

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Systemic Circuit

Blood flow from the heart to the rest of the body

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Artery

A blood vessel that carries blood from the heart to other parts of the body

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Conducting Arteries

Large, elastic blood vessels that cushions change in blood pressure

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Distribution Arteries

Medium-sized, muscular blood vessels that are often on sites of pressure points

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Arteriole

Smallest form of an artery, less muscular with a poor tunica externa; connects to capillary

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Capillary

Single cell thick, endothelial blood vessels connecting arterioles with venules; site of gas and nutrient exchange; can be turned on/off

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Continuous Capillary

Type of blood vessel that allows water and small molecules to diffuse through - larger molecules/cells do not fit. Completely lined & found in all tissues except epithelia and cartilage

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Fenestrated Capillary

This porous blood vessel is seen in the choroid plexus and endocrine organs

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Sinusoidal Capillary

Tiny blood vessels like fenestrated, but flatter and more irregular. Occurs in liver, bone marrow, spleen, endocrine organs, intestines, & kidneys

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Venule

Smallest form of a vein; connects to capillary

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Vein

A blood vessel that carries blood back toward the heart to get oxygenated; has valves to prevent back flow

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Tunica Interna

Innermost layer of blood vessels; made of endothilum & internal elastic membrane

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Tunica Media

Middle layer of blood vessels; consists of smooth muscle and loose connective tissue; thicker in arterties

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Tunica Externa

Outermost layer of blood vessels; made of fibrous connective tissue

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Vasoconstriction

Decrease in the diameter of blood vessels

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Vasodilation

Increase in the diameter of blood vessels

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Atrioventricular Valves

2 valves that allow blood into the ventricles; supported by chordae tendinae

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Semilunar Valves

2 valves that allow blood to leave the ventricles into the pulmonary artery & aorta

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Parietal Pericardium

The tough outermost layer of the pericardium that is attached to the diaphragm and the sternum

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Visceral Pericardium

The innermost layer of the pericardium that adheres to the heart

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Epicardium

The outer, serous membrane of the heart wall

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Myocardium

The middle, muscular layer of the heart wall

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Endocardium

The membrane that lines the cavities of the heart and forms part of the heart valves

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Right Atrium

Vena Cavae brings blood to the _____ of the heart

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Tricuspid Valve; Right Ventricle

After entering the right atrium, blood passes through the _____ on the way to the _____

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Pulmonary Semilunar Valve; Pulmonary Trunk

From the right ventricle, blood is pushed through the _____ into the _____

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2 Pulmonary Arteries

From the pulmonary trunk, the _____ takes the blood to the lungs

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4 Pulmonary Veins; Left Atrium

Now with fresh oxygen, the _____ returns the blood to the heart's _____

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Mitral Valve; Left Ventricle

From the left atrium, the blood has to pass through the _____ to go to the _____

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Aortic Semilunar Valve; Aorta

From the left ventricle, blood passes the _____ into the _____, where it is delivered throughout the body

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Systemic Arteries

The aorta carries blood to the _____

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Systemic Capillaries

The systemic arteries carries blood to the _____ where gas and nutrient exchange occurs

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Systemic Veins

The _____ finally returns the blood to vena cavae, where it must pass on the way to the heart

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Systole

The contraction of the chambers of the heart to drive blood into the aorta and pulmonary artery

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Diastole

The widening of the chambers of the heart between two contractions when the chambers fill with blood

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60 - 100 bpm

Normal pulse range

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Heart Murmur

An abnormal sound of the heart; usually a sign of abnormal function of the heart valves

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Specialized Muscle Cells

Cardiac cells (only 1%) that coordinates the heartbeat

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Contractile Cells

Cardiac cells (99%) that propel the blood

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Sinoatrial node

Initiates the heartbeat from the upper wall of the right atrium, causes atria to contract, natural pacemaker of the heart

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Bundle of His (AV Bundle)

Disperses the signal for ventricular contraction into the right and left bundle branches, then on to the apex and then U-turn into the Purkinje fibers

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Electrocardiogram (EKG)

Records electrical impulses from the heart

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P wave

Atrial depolarization on an EKG

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QRS complex

Ventricle depolarization and atrial repolarization on an EKG

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T wave

Ventricular repolarization on an EKG

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U wave

Thought to represent repolarization of the papillary muscles or Purkinje fibers on an EKG

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An action potential to bring Ca++; binding of Ca++ to troponin

Contractile cells need...

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Rapid Depolarization

Step 1 of contraction: Fast Na++ Channels open

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Plateau

Step 2 of contraction: Na+ channels close and slow Ca++ channels open and balance +/- ions

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Repolarization

Step 3 of contraction: Slow K+ channels opens as Ca++ channels close

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Atrial systole > atrial diastole > ventricular systole (1st & 2nd) > ventricular diastole (early & late)

Phases of the cardiac cycle

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Cardiodynamics

Movement & force during contractions

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End-Diastolic Volume (EDV)

The volume of blood that is in the ventricles before the heart contacts

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End-Systolic Volume (ESV)

The volume of blood remaining in the ventricles at the end of a contraction

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Cardiac Output

Blood pumped from each ventricle per minute

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Epinephrine

A hormone that increases heart rate & stroke volume due to stress

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Norepinephrine

A hormone than can increase blood pressure - can also increase heart rate and stroke volume

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T3 & T4

Thyroid hormones that regulate how your body uses energy - can increase heart rate and stroke volume

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Stroke Volume

Difference between the end-diastolic volume and the end-systolic volume (EDV - ESV)

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Preload

How much ventricles can stretch during diastole

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Contractility

The amount of force during a contraction per the preload; regulated by ANS, hormones & electrolytes level

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Afterload

Amount of tension the contracting ventricle produces to open the semilunar valves

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Rheumatic Fever

Reaction to strep infection that deteriorates the valves up to 20+ years later

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Pericarditis

Inflamed pericardial surfaces due to friction, increases fluid and causes cardiac tamponade

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Coronary Artery Disease

Blockage of coronary circulation, may cause ischemia and angina

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Bradycardia

Abnormally slow heartbeat

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Tachycardia

Abnormally rapid heartbeat

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Premature Atrial Contractions (PACs)

"Surprise" atrial contractions caused by stress, caffeine, and drugs

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Paroxysmal Atrial Tachycardia (PAT)

Abrupt episodes of rapid atrial contractions, ventricles can keep pace, HR over 180bpm

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Atrial Flutter

Atrial impulses <350 per min., not stable, often degenerates into a fibrillation

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Atrial Fibrillation

Impulses up to 500 per minute, atria quiver, ventricles do not keep up, can go unnoticed

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Premature Ventricular Contractions (PVCs)

"Surprise" ventricular contractions cause by epinephrine, drugs, and ion imbalances

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Ventricular Tachycardia

4 or more PVCs without a normal beat

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Ventricular Fibrillation

Ventricles quiver due to an uncoordinated contraction, to the point of no longer pumping; can cause cardiac arrest - can be fatal

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Mitral Valve Prolapse

Cardiopathy resulting from the mitral valve not regulating the flow of blood between the left atrium and left ventricle of the heart

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Myocardial Infarction

Destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle; heart attack

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Capillary Bed

A layer of tissue densely packed with capillaries. Blood travels through metarteriole or on to a thoroughfare channel

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Arteriole Anastamosis

Collateral arteries merge and creates a direct connection between an arteriole and a venule

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Metarteriole

Link between an arteriole and a venule; serves as a vascular shunt when precapillary sphincters are closed

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Thoroughfare Channel

Continuation of metarteriole at venule end that enables blood to bypass capillary bed. Lacks smooth muscle

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Hydrostatic Pressure

Created by a force pushing a liquid (blood). Pushes from high to low

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Blood Pressure

Arterial pressure

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Capillary Hydrostatic Pressure (CHP)

The pressure exerted by blood against the wall of a capillary

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