a nerve cell; the basic building block of the nervous system.
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Afferent (sensory) neurons
neurons that carry incoming information from the sensory receptors to the brain and spinal cord.
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Efferent (motor) neurons
neurons that carry outgoing information from the brain and spinal cord to the muscles and glands.
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Interneurons
neurons within the brain and spinal cord that communicate internally and intervene between the sensory inputs and motor outputs.
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Dendrite
the bushy, branching extensions of a neuron that receive messages and conduct impulses toward toward the cell body.
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Soma
cell body where the nucleus of the neuron is located.
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Axon
the extension of a neuron, ending in branching terminal fibers, through which messages pass to other neurons or to muscles or glands.
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Mylein sheath
a layer of fatty tissue segmentally encasing the fibers of many neurons; enables vastly greater transmission speed of neural impulses as the impulse hops from one node to the next.
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Glial cells
cells in the nervous system that support, nourish, and protect neurons.
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Synapse
the junction between the axon tip of the sending neuron and the dendrite or cell body of the receiving neuron. The tiny gap at this junction is called the synaptic gap or synaptic cleft.
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Synaptic vesicle
the vesicle that holds neurotransmitters at the synapse, then releases them into the synaptic gap.
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Neurotransmitters
chemical messengers that cross the synaptic gaps between neurons. When released by the sending neuron, neurotransmitters travel across the synapse and bind to receptor sites on the receiving neuron, thereby influencing whether that neuron will generate a neural impulse.
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Reuptake
a neurotransmitter's reabsorption by the sending neuron.
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Resting potential
when a neuron is completely polarized and not active.
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Action potential
a neural impulse; a brief electrical charge that travels down the axon (depolarizes the neuron as it travels through).
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Threshold
the level of stimulation required to trigger a neural impulse.
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All-or-none principle
neurons will only fire at full power, either all the way or not at all.
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Polarization
at resting potential a neuron is polarized. All sodium ions are on the outside of the neuron and all potassium ions are on the inside.
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Depolarization
occurs when action potential travels down the axon, causing the sodium ions to rush in (a mixing of different ions) causing depolarization and the energy to fire.
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Refractory period
a neuron's resting period after firing, when it recharges and can not fire again until recharged.
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Endorphins
"morphine within," natural, opiatelike neurotransmitter linked to pain control and to pleasure. Gives a "runner's high" feeling, released when injured or in pain.
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Dopamine
a neurotransmitter that influences movement, learning, attention, and emotion. Some stimulant substances mimic its effects. Too much is linked to schizophrenia, too little is linked to Parkinson's disease.
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Serotonin
a neurotransmitter that affects mood, hunger, sleep, and arousal. An undersupply is linked to depression.
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Acetylcholine
a neurotransmitter that enables muscle action, learning and memory. With Alzherimer's disease, Ach-producing neurons deteriorate. Blocking of it causes paralyses.
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Norepinephrine
a neurotransmitter that helps control alertness and arousal. An undersupply can cause a depressed mood.
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GABA
a major inhibitory neurotransmitter. Undersupply is linked to seizures, tremors, and insomnia.
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Glutamate
a major excitatory neurotransmitter, involved in memory.
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Blood-brain barrier
prevents materials (foreign substances, neurotransmitters and hormones in the body) in the blood from entering the brain or spinal cord
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Agonist
foreign substance that mimics certain neurotransmitters, having similar effects.
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Antagonist
foreign substance that blocks certain neurotransmitters, not allowing them to do their job.
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Nervous System
the body's speedy, electrochemical communication network, consisting of all the nerve cells of the peripheral and central nervous systems.
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Central Nervous System
the brain and the spinal cord.
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Peripheral Nervous System
the sensory and motor neurons that connect the central nervous system to the rest of the body.
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Somatic Nervous System
the division of the peripheral nervous system that controls the body's skeletal muscles.
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Autonomic Nervous System
the part of the peripheral nervous system that controls the glands and the muscles of the internal organs (such as the heart). Its sympathetic division arouses; its parasympathetic division calms.
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Sympathetic Nervous System
the division of the autonomic nervous system that arouses the body, mobilizing its energy in stressful situations; prepares the body for fight or flight response.
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Parasympathetic Nervous System
the division of the autonomic nervous system that calms the body, conserving its energy.
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Reflex
a simple, automatic response to a sensory stimulus, such as the knee-jerk response.
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Endocrine System
the body's "slow"chemical communication system; a set of glands that secrete hormones in the bloodstream.
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Hormones
chemical messengers that are manufactured by the endocrine glands, travel through the bloodstream, and affect other tissues.
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Pituitary gland
the endocrine system's most influential gland. Under the influence of the hypothalamus, the pituitary regulates growth and controls other endocrine glands.
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Lesion
tissue destruction. A brain lesion is a naturally or experimentally caused destruction of brain tissue.
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Electroencephalograph (EEG)
an amplified recording of the waves of electrical activity that sweep across the brain's surface. These waves are measured by electrodes placed on the scalp.
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CT Scan
a series of X-ray photographs taken from different angles and combined by computer into a composite representation of a slice through the body.
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PET
a visual display of brain activity that detects where a radioactive form of glucose goes while the brain performs a given task.
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MRI
a technique that uses magnetic fields and radio waves to produce computer-generated images of soft tissue. MRI scans show brain anatomy.
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FMRI (functional MRI)
a technique for revealing bloodflow and, therefore, brain activity by comparing successive MRI scans. FMRI scans show brain function.
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Brainstem
the oldest part and central core of the brain, beginning where the spinal cord swells as it enters the skull; the brainstem is responsible for automatic survival functions.
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Medulla
the base of the brainstem; controls heartbeat and breathing.
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Reticular formation
a nerve network in the brainstem that plays an important role in controlling arousal.
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Pons
part of the brainstem that influences sleep, dreaming, and respiration.
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Thalamus
the brain's sensory switchboard, located on top of the brainstem; it directs messages to the sensory receiving areas in the cortex and transmits replies to the cerebellum and medulla.
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Cerebellum
the"little brain" at the rear of the brainstem; functions include processing sensory input and coordinating movement output and balance.
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Limbic system
doughnut-shaped neural system (including the hippocampus, amygdala, and hypothalamus) located below the cerebral hemispheres; associated with emotions and drives.
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Amygdala
two lima bean-sized neural clusters in the limbic system; linked to emotion (specifically levels of aggression and fear).
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Hippocampus
a neural center that is located in the limbic system; helps process explicit memories for storage.
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Hypothalamus
a neural structure lying below (hypo) the thalamus; it directs several maintenance activities (eating, drinking, body temperature, sex drive), helps govern the endocrine system via the pituitary gland, and is linked to emotion and reward.
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Cerebral cortex
the intricate fabric of interconnected neural cells covering the cerebral hemispheres; the body's ultimate control and information-processing center.
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Corpus callosum
the large band of neural fibers connecting the two brain hemispheres and carrying messages between them.
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Frontal lobes
portion of the cerebral cortex lying just behind the forehead; involved in speaking and muscle movements and in making plans and judgments. Also involved in personality.
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Motor cortex
an area at the rear of the frontal lobes that controls voluntary movements.
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Parietal lobes
portion of the cerebral cortex lying at the top of the head and toward the rear; receives sensory input for touch and body position.
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Somatosensory cortex
area at the front of the parietal lobes that registers and processes body touch and movement sensations.
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Occipital lobes
portion of the cerebral cortex lying at the back of the head; includes areas that receive information from the visual fields.
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Primary Visual cortex
area at the back of the occipital lobes that process visual information.
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Temporal lobes
portion of the cerebral cortex lying roughly above the ears; includes the auditory ares, each receiving information primarily from the opposite ear.
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Primary Auditory cortex
area in the temporal lobes responsible for receiving auditory information.
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Association areas
areas of the cerebral cortex that are not involved in primary motor or sensory functions; rather, they are involved in higher mental functions such as learning, remembering, thinking, and speaking.
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Aphasia
impairment of language, usually caused by left hemisphere damage either to Broca's area (impairing speaking) or to Wernicke's area (impairing understanding).
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Broca's Area
controls language expression - an area, usually in the left frontal lobe, that directs the muscle movements involved in speech.
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Wernicke's area
controls language reception - a brain area involved in language comprehension and expression; usually in the left temporal lobe.
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Plasticity
the brain's ability to change, especially during childhood, by reorganizing after damage or by building new pathways based on experience.
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Long-term potentiation (LTP)
an increase in a synapse's firing potential after brief, rapid stimulation. Believed to be a neural basis for learning and memory.
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Consciousness
our awareness of ourselves and our environment
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Circadian rhythm
the biological clock; regular bodily rhythms (for example, of temperature and wakefulness) that occur on a 24-hour cycle
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Sleep
periodic, natural loss of consciousness-as distinct from unconsciousness resulting from a coma, general anesthesia, or hibernation
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NREM sleep
non-rapid eye movement sleep; encompasses all sleep stages except for REM sleep
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REM sleep
rapid eye movement sleep; a recurring sleep stage during which vivid dreams commonly occur. Also known as paradoxical sleep, because the muscles are relaxed (except for minor twitches) but other body systems are active
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Insomnia
recurring problems in falling or staying asleep.
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Narcolepsy
a sleep disorder characterized by uncontrollable sleep attacks. the sufferer may lapse directly into REM sleep, often at inopportune times
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Sleep apnea
a sleep disorder characterized by temporary cessations of breathing during sleep.
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Night terrors
a sleep disorder characterized by high arousal and an appearance of being terrified; unlike nightmares, night terrors occur during Stage 4 sleep, within two or three hours of falling asleep and are seldom remembered
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Somnambulism
sleep walking
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Dream
a sequence of images, emotions, and thoughts passing through notable for their hallucinatory imagery, discontinuities, and incongruities, and for the dreamer's delusional acceptance of the content and later difficulties remembering it.
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Manifest content
according to Freud, the remembered storyline of a dream, (as distinct from its latent, or hidden, content).
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Latent content
according the Freud, the underlying meaning of a dream (as distinct from its manifest content).
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REM rebound
the tendency for REM sleep to increase following REM sleep deprivation (created by repeated awakenings during REM sleep).
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Activation-synthesis hypothesis
Suggests that in the brain engages in a lot of neural activity that is random. Dreams make sense of this activity.
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Information-processing theory
Dreams may help sift, sort, and fix day's experiences in our memories.
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Psychoactive drug
a chemical substance that alters perceptions and moods.
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Tolerance
the diminishing effect with regular use of the same dose of a drug, requiring the user to take larger and larger doses before experiencing the drug's effect.
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Withdrawal
the discomfort and distress that follow discontinuing the use of an addictive drug.
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Physical dependence
a physiological need for a drug, marked by unpleasant withdrawal symptoms when the drug is discontinued.
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Psychological dependence
a psychological need to use a drug, such as to relieve negative emotions.
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Addition
compulsive drug craving and use, despite adverse consequences.
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Depressants
drugs (such as alcohol, barbiturates, and opiates) that reduce neural activity and slow body functions.
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Barbiturates
drugs that depress the activity of the central nervous system, reducing anxiety but impairing memory and judgment.
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Opiates
opium and its derivatives, such as morphine and heroin; they depress neural activity, temporarily lessening pain and anxiety.
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Stimulants
drugs (such as caffeine, nicotine, and the more powerful amphetamines, cocaine, and Ecstasy) that excite neural activity and speed up body functions.
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Amphetamines
drugs that stimulate neural activity, causing speeded-up body functions and associated energy and mood changes.