Chapter 4

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201 Terms

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TISSUE
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is a group of cells having similar origin that work together to  perform a specific function 
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• __EPITHELIAL TISSUE__ 
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o Widespread throughout the body 
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• __EPITHELIAL TISSUE__ 
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o Composed almost entirely of cells 
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• __EPITHELIAL TISSUE__ 
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o Form continuous sheets held together by tight junctions and  desmosomes 
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• __EPITHELIAL TISSUE__ 
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o Cells are mostly compact and tightly fitted together 
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• __EPITHELIAL TISSUE__ 
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o Tissue forms lining of organs or body cavities 
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• __EPITHELIAL TISSUE__ 
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o Supported by fibrous connective tissue 
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• __EPITHELIAL TISSUE__ 
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o Tissues are non-vascular but with nerve innervations 
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• __EPITHELIAL TISSUE__ 
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o Lost cells are rapidly replaced by cell division 
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• __EPITHELIAL TISSUE__ 
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o The underside of the tissue is mostly attached to connective tissues by  a __Basement Membrane__ 
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o When the cells are organized in more than one layer, it is called 
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__Stratified Epithelium__ 
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Squamous
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 when cells are flat and irregular 
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When the cells are arranged in a single layer, it is called
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__Simple__  __Epithelium__ 
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Cuboidal
when cells are cube shaped
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Columnar
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when cells are elongated like columns 
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__Epithelial tissue__ 
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o Functions: protection, absorption, secretion, sensation, etc. 
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• __Simple Squamous Epithelium__ 
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o Single layer, flat cells with disc shaped nuclei 
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• __Simple Squamous Epithelium__ 
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o Cells are compact 
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• __Simple Squamous Epithelium__ 
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o Provides protection for underlying tissues 
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• __Simple Squamous Epithelium__ 
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o Helps in diffusion and filtration 
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• __Simple Squamous Epithelium__ 
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o Provides a slick, friction-reducing lining in lymphatic and  cardiovascular systems for lymph and blood flow 
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• __Simple Squamous Epithelium__ 
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o Mainly found in the lining of blood vessels, lymph vessels, lung  alveoli, wall of blood capillaries, membranes that line the body  cavities, etc.
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• __Simple Cuboidal Epithelium__ 
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o Single layer cube shaped cells with large, spherical central nuclei o Mainly found in the lining of ovaries, kidney tubules, duct of secretory portions of various small glands 
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• __Simple Cuboidal Epithelium__ 
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o Functions: protection, secretion, absorption, etc. 
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• __Simple Columnar Epithelium__ 

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o Single layer of elongated cells with oval nuclei 
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• __Simple Columnar Epithelium__ 
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o Non-ciliated type lines digestive tract and gallbladder 
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• __Simple Columnar Epithelium__ 
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o Ciliated type lines upper respiratory tract, small bronchi, uterine tubes,  and some regions of the uterus 
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• __Simple Columnar Epithelium__ 
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o Goblet cells are often found in this layer 
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• __Simple Columnar Epithelium__ 
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o Mainly found in the lining of digestive tract, uterus, upper part of  respiratory tract, etc. 
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• __Simple Columnar Epithelium__ 
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o Functions: protection, mucus secretion, mucus movement, egg  movement, enzyme secretion, absorption, etc.
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• __Pseudostratified Columnar Epithelium__ 
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o Single layer cells with different heights and some don’t reach the free  surface 
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• __Pseudostratified Columnar Epithelium__ 
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o Nuclei are located at different layers 
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• __Pseudostratified Columnar Epithelium__ 
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o Tissue appears to be in multiple layers 
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• __Pseudostratified Columnar Epithelium__ 
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o Mainly found in the respiratory passages (ciliated) and sperm carrying  duct of male reproductive system (non-ciliated) 
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• __Pseudostratified Columnar Epithelium__ 
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o Functions: protection, mucus secretion, mucus movement, etc.
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• __Stratified Squamous__ `Epithelium` 
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o Many layers of flat cells
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• __Stratified Squamous__ `Epithelium` 
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o Cells are compact 
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• __Stratified Squamous__ `Epithelium` 
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o Mainly found in the lining of skin, mouth, throat, vagina, anal canal,  etc. 
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• __Stratified Squamous__ `Epithelium` 
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o Cells may be keratinized – as found in skin 
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• __Stratified Squamous__ `Epithelium` 
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o Function: protection 
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• __Stratified Columnar Epithelium__ 
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o Many layers of cells 
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• __Stratified Columnar Epithelium__ 
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o Upper layer cells are elongated 
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• __Stratified Columnar Epithelium__ 
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o Lower layer cells are cuboidal 
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• __Stratified Columnar Epithelium__ 
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o Mainly found in some areas of pharynx, male reproductive system, etc. 
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• __Stratified Columnar Epithelium__ 
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o Function: protection
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• __Stratified Cuboidal Epithelium__ 
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o Two – three layers of cube shaped cells 
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• __Stratified Cuboidal Epithelium__ 
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o Lines the wall of a lumen 
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• __Stratified Cuboidal Epithelium__ 

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o Cells are compact 
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• __Stratified Cuboidal Epithelium__ 
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o Mainly found in the lining of ducts of sweat gland, salivary gland,  pancreas, mammary gland, etc. 
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• __Stratified Cuboidal Epithelium__ 
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o Functions: protection, diffusion, filtration, etc.
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• __Trasitional Epithelium__ 
In response to increased tension, these cells can change their shape
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• __Trasitional Epithelium__ 
Cells are mostly cube shaped or dome shaped under normal condition
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• __Trasitional Epithelium__ 
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Under increased tension, they become flat allowing distention of the  bladder 
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• __Trasitional Epithelium__ 
 Mostly found in the lining of uterus, urinary bladder, urethra, etc.
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• __Trasitional Epithelium__ 
Functions: protection, preventing reverse diffusion in the urinary  bladder and urethra, etc.
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• __Glandular Epithelium__ 
Composed of specialized cells to secrete various substances
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• __Glandular Epithelium__ 
Mainly found within the cells of the columnar or cuboidal epithelial  cells 
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• __Glandular Epithelium__ 
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o Constitutes endocrine and exocrine glands 
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Merocrine
when products are secreted by exocytosis (e.g., pancreas,  sweat, salivary glands, etc.)
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Holocrine
when products are secreted by the rupture of gland cells  (e.g., sebaceous glands)
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• __Glandular Epithelium__ 
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o Function: secretion 
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• __CONNECTIVE TISSUE__ 
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o Most abundant type 
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• __CONNECTIVE TISSUE__ 
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o Derive from embryonic mesenchymal tissue (Gel-like ground  substance with fibers and star-shaped mesenchymal cells) 
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• __CONNECTIVE TISSUE__ 
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o Supports other tissues or organs 
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• __CONNECTIVE TISSUE__ 
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o Protects soft, delicate organs
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• __CONNECTIVE TISSUE__ 
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o Stores materials 
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• __CONNECTIVE TISSUE__ 
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o Transports materials 
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• __CONNECTIVE TISSUE__ 
o Tissue may contain Fibroblast Cells, Mast Cells, and Macrophage  Cells
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o Mast cells produce
histamine and heparin  
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o Macrophage cells have
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phagocytic functions 
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• __Loose Connective Tissue__ 
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o Also called __Areolar Tissue__ 
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• __Loose Connective Tissue__ 
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o Widely distributed in the body 
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Fibroblast cells produce
collagen (protein) and elastin (protein)
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### • __Loose Connective Tissue__ 
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o Forms delicate, thin membranes throughout the body 
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### • __Loose Connective Tissue__ 
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o Wraps around the blood vessels, muscles, nerves, etc. 
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### • __Loose Connective Tissue__ 
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o Stores fluid and salts 
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### • __Loose Connective Tissue__ 
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o Together with the adipose tissue, forms subcutaneous layer
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• __Dense Fibrous Connective Tissue__ 
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o Mostly consists of closely packed collagen fibers along with a  network of some elastin fibers 
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• __Dense Fibrous Connective Tissue__ 
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o Stronger but less flexible than the loose fibers 
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In Dense Regular Fibrous tissue
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collagen fibers are arranged in a  regular parallel fashion with a few elastic fibers 
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• __Dense Fibrous Connective Tissue__ 
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o Mainly found in tendons, ligaments, aponeuroses, etc. 
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In Dense Irregular Fibrous tissue
collagen fibers are arranged in an  irregular fashion with a few elastic fibers
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• __Dense Fibrous Connective Tissue__ 
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o Mostly found in the dermis, submucosa of the digestive tract, fibrous  organ coverings, etc. 
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• __Dense Fibrous Connective Tissue__ 
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o Tissues provide support and structural strength 
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• __Dense Fibrous Connective Tissue__ 
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o Tissues are non-vascular  
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• __Elastic Fibrous Connective Tissue__ 
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o Mostly consists of highly flexible elastin fibers along with some  collagen fibers 
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• __Elastic Fibrous Connective Tissue__ 
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o Fibers are parallel, make bundles, and may have branches
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• __Elastic Fibrous Connective Tissue__ 
o Found in attachments between vertebra, wall of blood vessel, areas of  heart and lung, etc.
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• __Reticular Connective Tissue__ 
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o Mostly consists of thin collagen fibers 
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• __Reticular Connective Tissue__ 
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o Fibers make network 
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• __Reticular Connective Tissue__ 
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o Supports structure of delicate organs – such as liver, spleen, lymph  nodes, bone marrow, etc.
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• __Adipose Tissue__ 
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o Cells are called __Adipocyte cells__ 
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• __Adipose Tissue__ 
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o Tissue is made of closely packed adipocytes 
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• __Adipose Tissue__ 
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o Immature cells are star shaped 
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• __Adipose Tissue__ 
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o Cells accumulate fat droplets and become round shaped as they  mature 
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• __Adipose Tissue__ 
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o Fat droplets combine to make a large drop of fat that occupies most of  the cell space 
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White fat
is the common body fat commonly found under the skin,  around kidneys, within abdomen, in breasts, etc.
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• __Adipose Tissue__ 
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o Functions: organ protection, insulation, storage of energy, etc.
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• __Cartilage__ 
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o Cells are called __Chondrocytes__ 
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• __Cartilage__ 
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o Immature cells are __Chondroblasts__