NURS 288 - Quiz 3

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Conflict Management in Nursing
Conflict management is a skill that nurses can sustain and develop which in turn will contribute to effectiveness in nursing practice

Conflict management is a skill that managers look for in new hires.
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What are the 6 impacts of effective conflict management?
-Minimize the negative impacts of conflict
-Help to create a trusting and healthy workplace
-Improve interpersonal relationships and team work
-Improve job satisfaction & staff retention
-Inspire innovation and creative strategies to address challenging issues
-Improve quality of patient care delivery and patient outcomes
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Rahim & Bonoma's Five Dimensions of Conflict Management Styles
Collaborating, accommodating, dominating, avoiding, and compromising
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Collaborating
Direct and cooperative management with aim to reach a solution collaboratively
-Everyone contributes tot he solution and the solution is more than the sum of the parts

High assertation and high collaboration
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Accmomdating
Passive and accommodating, follower
-Everything they wanted and nothing from you

Low assertation and high collaboration
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Dominating
Force behaviours on others, self-concerned

High assertation and low collaboartion
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Avoiding
Tendency to sidestep conflicts

Low assertation and low collaboration
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Compromising
Aim to reach a mutually agreed decision
-50/50, meet halfway

Mid-way in assertation and collaboration
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What are strategies to address relational conflict?
Speak up, check-in meetings
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What are strategies to address task conflicts?
"What did we agree to last time?"
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What are strategies to address process conflict?
A group that eats together lasts
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Strategy to Support Team Functioning - Create Interdependence
Perform meaningful group tasks that are complex, that require members to collaborate in order to succeed

Ensure team members are using project management tools with major milestones and accountabilities
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Strategy to Support Team Functioning - Group Functioning and Feedback
Build on opportunities for structured monitoring of group functioning and feedback
-Set clear goals and expectations
-Review what went well?
-What areas could we improve?
-Keep short accounts
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What does U=U mean?
Undetectable = utransmittable
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PrEP
HIV pre-exposure prophylaxis

Prevents HIV infection
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CaSP Characteristics (7)
-Capitalize on strengths
-Decrease the potential of encountering stressors
-Limit the impact or effect of stressors
-Build the capacity of the community
-Integrates public health and nursing
-Involves the principles of primary care
-Partnership and participation
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Groups Inequitably Impacted by HIV (5)
-gbMSM
-PWID
-Indigenous people
-ACB communities
-Transgender populations
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What are the 7 DoH related to HIV risk?
-Race
-Sexuality
-Gender identity
-Income and social status
-Education
-Health services
-Personal health practices & coping skills
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Community Engagement Characteristics (5)
Empowerment - increasing ability of community members to influence community circumstances

Participation - supporting community members to take part in decision making about their community

Inclusion - recognizing that some community members have less influence than others

Self-determination - supporting the rights of citizens to make their own choices

Partnership - agencies can contribute and work together to make the most of the available resources
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In relational to the establishment of PrEP, what was the CaSP analysis?
Need for additional harm reduction strategies at multiple levels
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Community Diagnosis for the Risk of HIV Infection (Etiology and Manifestations)
Etiology - financial barriers in accessing PrEP, high risk behaviours

Manifestations - disproportionate rates of new HIV infections among target groups
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Considerations When Prioritizing Community Diagnoses (6)
-Magnitude of concern expressed by members of the community
-Political will to address the concern
-Extent of existing resources to deal with the concern
-Potential for success in solving the problem with existing resources
-Need for specialized education or training
-Extent of additional resources and policies needed for equitable, cost-effective, and efficient response
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Goal of HIV PrEP Intervention
Make PrEP more accessible to adults who are at high, ongoing risk of HIV infection
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How do we plan for this intervention?
Ottawa Charter Action Areas
-Build healthy public policy, create supportive environments, develop personal skills, reorient health services
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What are the 3 guiding principles of the Alberta HIV PrEP program?
Equitable access to the full range of HIV prevention strategies (including PrEP) for people at risk of HIV infection

PrEP should be discussed and considered for all patients who fit the eligibility criteria and wish to optimize their HIV prevention strategies

PrEP should be accessible to all Albertans at risk of HIV regardless of geographic location
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What are 3 common concerns about PrEP?
PrEP can lead to antiviral drug resistance
-HIV screening

PrEP will lead to condomless sex and increase in STI incidence
-Education
-Regular STI testing of PrEP patients
-Immunizations

PrEP can cause life-threatening flare of chronic HBV infection
-Consult with hepatologist
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What are the interventions of the PrEP Program? (8)
-Research and evaluation
-Building coalitions & networks
-Policy development and implementation
-Community development
-Building capacity
-Outreach care/counselling and harm reduction
-Communication, surveillance, screening
-Case management, referral and follow up, health education
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3 Phases of PrEP Implementation
Phase 1: Prepare HCP with knowledge
Phase 2: Shadowing opportunities and PrEP processes in service
Phase 3: PrEP appointments available, increased involvement of nurses and MD
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PrEP and Risk Reduction (+What type of prevention is PrEP?)
Goal: risk reduction within an at risk population

PrEP targets clients who are most at risk, is risk reduction, is secondary prevention
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Risk Assessment
The systematic process for describing and quantifying the level of expose to a substance that will result in increased risks to health

E.g., risk questionnaire
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Risk Management
Interventions to reduce risk such as enhancing public awareness through to legislation
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Risk Communication
Getting the word out about precautions
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What are the 4 aspects of PrEP evaluation at SRH?
-Are we reaching the highest risk populations
-Medication adherence?
-Service delivery?
-Dissemination of evaluation data
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PrEP Future Directions + Barriers
It is possible that by 2025 there may be at least one option for long-acting PrEP

Potential barriers include race and socioeconomic status
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Pharmacology
The study of drugs and their interactions with the body
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What is a drug? (4)
Any chemical that has an influence on the physiological processes of a living organism

Exogenous (produced outside organism)

Non-nutritive substance that influences body function

Used interchangeably with medication
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Pharmacodynamics
The mechanism of drug action (what the drug does to the body) and the relationships between drug concentration and the body's response

Concerned with alterations of normal physiological functioning by the influence of medications
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Therapeutic Effect
Therapeutic effect of a drug = creates a positive change when the physiological system is flawed
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3 Types of Drug Mechanism of Action (+what can a dug not do?)
Through receptors, through enzymes, through non-selective interactions

Cannot cause a cell or tissue to perform a function not part of its natural physiology
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What does a drug modify at the site of action?
At site of action, can modify at which the cell or tissue functions - increase or decrease; or can modify the strength of function
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Receptor
A drug's specific target
-Usually a protein located on the surface of a cell membrane or within the cell

Most drugs exert their effects by chemical binding with receptors at a cellular level

Cell membrane is like a light socket
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Agonist
A drug that binds with a receptor and elicits an appropriate response (active or induce)
-Can be partial or full

Activates the cell to do something
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Antagonist
A drug that binds to a receptor and inhibits cell function by blocking the receptor (inhibit)
-Can be partial or full
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Affinity
The degree to which the drug attaches and binds with the receptor

The stronger the affinity the greater the response from the cell or tissue
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Pharmacodynamics and Enzymes (Selective Interaction)
Enzymes catalyze biochemical reactions in a cell

Selective interaction - drug inhibits or enhances the action of a specific enzyme

The drug binds to the enzyme and alters the enzyme's interaction with its normal target molecules in the body
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Non-Selective Interactions (+Examples)
Does not interact with receptors or enzymes to alter a physiological or biological function of the body

Target to alter cell membranes and cellular processes

Example:
-Cancer drugs, antibiotics
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Pharmacokinetics
The study of what the body does to the drug

The movement of the drug into, through, and out of the body

Drug absorption into, distribution and metabolism within, excretion out from a living organisms (ADME)
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What is pharmacokinetics dependent on? (3)
Patient factors (renal function, hepatic function, genetic makeup, age, ethnicity, etc.)

Route of administration

Chemical properties of drug
-Molecule size, lipid solubility, ionization of molecule
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Absorption + what is rate of absorption determined by?
The movement of the drug from the site of administration into the bloodstream for distribution to the tissues

Rate is determined by form of drug and heavily by the route of administration: Correct - Aligned
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Bioavailability (+what is it determined by?)
Extent/amount of drug absorbed

Influenced by route of administration
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Enteral Route (+what influences it?)
Drug is absorbed through the GI tract (oral, buccal, sublingual, rectal, nasogastric, gastronomy tube)

Influenced by form of drug, presence of food/liquid ingested with drug, acidity of stomach, motility of GI tract, status of absorptive surface, rate of blood flow
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First-Pass Effect (+what does it reduce?)
Initial metabolism of the drug absorbed from the GI tract, in the liver, before it reaches the systemic circulation through the bloodstream
-Oral route especially

Reduces bioavailability
-Reduces how much med is available
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Topical Route
Med applied to skin or mucous membrane - local effect (skin, eyes, nose, ears, respiratory tract, urinary tract, vagina, rectum, transdermal patch)
-Absorption rate differs between routes

Avoids 1st-past effect

Medication applied to a circumscribed area of the body
-Intended to only affect area applied to
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What are the 3 types of topical applications?
Dermatological preparations (skin)

Instillations and irrigations (body cavity or orifice)

Inhalation (resp. tract)
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Parenteral (+Benefit)
Routes other than enteral and topical
-IM, IV, SC, ID
-Less commonly intra-arterial, intraosseous, intrathecal, or intracardiac

Bypasses 1st-past effect - benefit
-Drugs administered by IV enter directly into systemic circulation and have direct access to the rest of the body
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What influences the rate of absorption? (4)
Drug concentration and dose (higher dose, higher response)

GI tract (motility, food, gut health)

Blood flow to site of absorption

Drug interactions
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Distribution (+Drugs in the Bloodstream)
Transport of drug in the body by the bloodstream to intended site of action
-Drugs are not passive agents - interact with blood and can be chemically and physically changed before reaching target

As soon as drug enters circulation, metabolism and excretion begin: kidney and liver
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What is distribution influenced by? (4)
Blood flow to tissues

Tissue storage

Drug solubility

Drug protein binding
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What areas is there rapid and slow distribution? +Where will the drug be attracted?
Areas well-supplied with blood vessels have rapid distribution (heart, lungs, kidney, liver, brain)
-Areas not as well-supplied have slower distribution (skin, muscle, fat)

Chemical and physical properties of a drug will largely determine the area of the body to which the drug will be attracted
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Special Barriers
Limit distribution

Blood-brain barrier and fetal-placental barrier
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Distribution and Drug Solubility
Physical properties of a drug influence how it moves through the body

Lipid solubility is an important characteristic because it determines how quickly a drug is absorbed, mixes within the blood stream, crosses membranes, and becomes localized in body tissues
-Lipid soluble drugs absorb more rapidly than water soluble drugs because they are not limited by the barriers that normally stop water-soluble drugs
-Thus, they are more completely distributed to body tissues
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Distribution and Protein Binding of Drugs
Many drugs bind reversibly to plasma proteins (albumin) to form drug-protein complexes that are too large to cross capillary membranes

The bound drugs continue to circulate in the bloodstream and are unavailable to their site of action until they become unbound.
-Only unbound or free drugs can reach their target or be excreted by the kidneys

The number of binding sites on a plasma protein is limited
-Drugs may be highly protein bound or not
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Metabolism (what are drugs changed into?)
Biotransformation or detoxification

Process of chemically changing a drug molecule into:
-Inactive metabolite by enzymes (usually in liver) (less pharmcoactivity)
-Into more soluble compounds (to excrete in urine) (most cases)
-Less commonly into more potent pmetabolites
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What does metabolism involve? +What is the primary site?
Involves hundreds of complex biochemical pathways and reactions that alter the structure and function of drugs, nutrients, vitamins, and minerals.

Primary site of drug metabolism is the liver, though the kidney and intestinal tract also have high metabolic rates
-The types of metabolic reactions are specific to the type of cell
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Importance of Medical History W/ Metabolism
If a patient has liver or kidney disease, they may not metabolize the medication adequately and the medication may reach toxic levels.

You need to be aware of your patient's medical history AND how medications are metabolized
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Excretion (what does the rate determine, pathological states, and route of excretion)
Elimination of drugs
-Drugs will continue to act on the body until they are either metabolized to an inactive form or removed from the body by excretion

The rate of excretion determines its concentration in the blood and its duration of action

Pathological states, especially liver or kidney disease, often increase the duration and intensity of drug action in the body because they interfere with excretion

Drugs are excreted via the kidneys, liver, lungs, and glandular secretions (e.g. saliva or breastmilk)
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What is the ultimate goal of pharmacology and time?
The goal is to achieve consistent levels of drug in the body
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Onset, Peak, Duration of Action, and Half-Life
Describe the reactions of the body to the drug, the drug's effects

Onset - time required for the drug to elicit a therapeutic response

Peak - time required for a drug to reach its maximum therapeutic response

Duration of Action - length of time that the drug concentration is sufficient (without more doses) to elicit a response

Half-Life - time it takes for 1/2 of a given amount of medication in the body to be removed
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Med Concentration Terms (Peak vs. Trough Level, Toxcitiy)
Peak Level - Highest blood level of a drug (strongest effect of med)

Trough Level - Lowest blood level of a drug (lowest effect)

Minimum Effective Cncentration

Toxicity - Peak blood level is too high; drug becomes poisonous
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Half-Life (what does it measure + what is it used to determine?)
Time it takes for 1/2 of a given amount of medication in the body to be removed

Measures rate at which drug is eliminated from the body

Used to determine the steady state (when the drug eliminated is equal to the drug absorbed per dose
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Adverse Drug Effects vs. Side Effects
Although every drug has the potential to produce adverse events, most pharmacotherapy can be conducted without significant undesirable effects

Adverse drug effects are undesirable, unfavorable, unintended and potentially harmful reaction caused by the administration of a medication

Side effects are types of drug effects that are predictable, secondary to the intended purpose and may occur even at therapeutic doses

Difference is severity, predictability, and potential harm
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What are the 5 types of med orders?
STAT (immediate)

Single order (one time dose)

Standing order: may or may not have a termination date.

PRN: permits nurse to give medication when needed (in nurse's judgement)

Protocol order: set of criteria or orders under which medication is to be given (re: insulin)
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Abbreviations
Know accepted ones, be aware of dangerous ones
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PO
Per oral (by mouth)
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NPO
Nothing by mouth (nil per os)
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OD
Once daily (not acceptable although still used)
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BID
Twice daily
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TID
Three times a day
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QID
Four times a day
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HS
Before bed
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Q2H
Every 2 hours
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STAT vs. PRN
Immediately vs. when needed
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AC
Before meals (ante cibum)
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PC
After meals (post cibum)
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What do you need to know before administering a med? (10)
-Name of medication (generic and brand name)
-Purpose for taking the medication - indication
-Drug action
-Intended effect - therapeutic effect
-Pharmacokinetics - ADME
-Is there a reason they should not take the medication? (contraindications, allergies)
-What should I watch out for? (adverse reactions/side effects
-Route? Dose? Safe dose?
-Onset, peak, duration
-Is there anything I need to monitor? Assess for? Evaluate? (nursing Implications)
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What are the three checks?
1. Compare the medication label to the MAR as you remove the drug from the storage area
2. Compare the medication label to the Mar as you prepare each drug
3. Compare the medication label to the MAR at the patient beside before administering each drug
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What are the ten rights of medication administration?
-Right patient/client
-Right medication
-Right dose
-Right time
-Right route
-Right client education
-Right documentation
-Right to refuse
-Right assessment
-Right Evaluation
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Why is it important to build trusting relationships with clients?
So they will share what OTC medications, herbal remedies, and substances they are using (e.g., drug interactions)

Use resources such as the Natural and Non-prescription Health Products Directorate (NNHPD) to find up to date information
-Vitamins and minerals
-Herbal remedies
-Homeopathic medicines
-Traditional medicines such as traditional Chinese medicines
-Probiotics
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What are 12 individual factors that influence drug action?
-Income and Social Status
-Social Support Networks
-Social Environments
-Education
-Working Conditions
-Physical Environments
-Biology and Genetics
-Personal Health Practices and Coping Skills
-Healthy Childhood Development
-Health Services
-Culture
-Gender

Similar to SeDoHs
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Lifespan Considerations - Pregnancy
Awareness that certain medications are harmful to the fetus
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Lifespan Considerations - Infants and Children
Require smaller dosages due to smaller body size and immaturity of organs; may not tolerate certain medications

Increased susceptibility to drug reactions and toxicity

Dosage calculations are required and are based on age, weight and body surface area (BSA)
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Lifespan Considerations - Adolescents/Adults
Adolescents: may have adverse reactions to previously tolerated medications

Adults: may develop new allergic reactions to previously tolerated medications

Awareness that chronic illnesses have potential to alter functioning of certain organs/systems that may influence individual's reaction to certain medications
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Lifespan Considerations - Older Adults
65 years of age or olde

Consume a larger proportion of all medications than do other population group

Lower blood protein levels (metabolism)

Kidneys do not work as effectively (excretion)

Combination of prescription, Over-the-Counter (OTC) medications, Herbals, Vitamins

At risk for polypharmacy
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Polypharmacy
Administration of more medications than clinically indicated, representing unnecessary drug use

"Prescribing cascade"- the development of adverse effects from one or more of the medications taken for which another drug is prescribed

Individual takes prescription medications for disease conditions—usually comorbidities such as CHF, HTN, DM, HTN— requiring multiple medications

Increased risk for ADR
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OTC drugs, Herbals, Vitamins, Minerals and Laxatives
No prescription needed--self-medication

Most commonly used OTCs: Analgesics, Laxatives, Nonsteroidal anti-inflammatory drugs (NSAIDs)

Patient education required
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Analgesics
Response is individual—what works for one person may not work for another

Beware of side effects

Beware of similar products in different medications

Should not be used for extended length of time—have recommendations on packages

Acetaminophen—fever, headaches, common aches and pains

NSAIDs—pain and fever relief, reduce inflammation (swelling) from muscle strains and arthritis
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Laxitives
Relieve and prevent constipation

Overuse can lead to bowel dependency and decreased function of bowels

Can interfere with absorption of some medications and nutrients; electrolyte imbalance

Encourage fiber-rich foods, fluids, exercise

Natural is best
-May be required along with opioid script
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Herbals, Vitamins, Minerals
Beware of interactions with other medications, interference with diet
Under the Natural Health Products Regulations, natural health products (NHPs) are defined as:
-Vitamins and minerals
-Herbal remedies
-Homeopathic medicines
-Traditional medicines such as traditional Chinese medicines
-Probiotics
-Other products like amino acids and essential fatty acids
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Communicable Diseases
Illness caused by an infectious agent or resulting from direct or indirect transmission of the infectious agent or its products from an infected individual or via an animal, vector or the inanimate environment to a susceptible animal or human host
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What are factors key to controlling infection?
Understanding the infectious agents, the host and the environment (epidemiological triangle