secrete TSH, FSH, ACTH, LH. Note there are more acidophils than basophils. Chromophobes are most abundant.
3
New cards
macula densa
part of DCT, bead-like (dense nuclei) structure at vascular pole. Secretes renin which is a vasoconstricter. Key role in maintaining blood pressure.
4
New cards
vasa rectae
run along collecting tubules to supply nutrients to them, also exchange of water and electrolytes.
5
New cards
glomerulus
filtration of blood, only removing urine. Note fenestrated endothelium only allows small proteins through. Larger proteins e.g. albumin are retained.
6
New cards
Loop of Henle
further concentrate the glomerular filtrate by osmosis.
7
New cards
PCT
resorbs about 75% of water, glucose, amino acids, vitamins and sodium ions from glomerular filtrate.'
8
New cards
DCT
resorption of sodium and only a little water.
9
New cards
sertoli cells
supporting cells, phagocytise excess cytoplasm released by maturing sex cells
10
New cards
Leydig (interstitial) cells
lie between seminiferous tubules and produce testosterone.
11
New cards
seminiferous tubules
contain developing sperm cells
12
New cards
epididymis
stores sperm for maturation
13
New cards
prostate gland acini
secrete enzymes, acid phosphatase and fibrinolysin; watery substances rich in zinc and citric acid. Fibrinolysin liquefies the congealed sperm in the female, allowing it to move from the vagina to uterus.
14
New cards
glands of Littre
secrete mucous that lubricate the penile urethra
15
New cards
ciliary body
contains ciliary muscle that regulates len accomodation i.e. controls len thickness via zonula fibres
16
New cards
vitreous body
shock absorber
17
New cards
Bowman's membrane
provides strength, barrier to spread of infections
18
New cards
corneal endothelium
allows metabolic exchange between cornea and aqueous humor
19
New cards
ciliary epithelium
secretes aqueous humor
20
New cards
sphincter pupillae m.
contracts the pupil, determining its size.
21
New cards
canal of schlemm
drains the humor
22
New cards
ora serrata
transitiona between visual + non visual retina
23
New cards
Tarsal (Meibomian) gland
very large sebaceous glands with sebum-type secretions
24
New cards
apocrine sweat glands (Moll)
put out pheromomones
25
New cards
Sebaceous glands (zeis)
smaller sebaceous glands than Tarsal gland, on eyelid
26
New cards
fovea
area of greatest visual acuity
27
New cards
retinal pigment epithelium
absorption of light
28
New cards
mucosa (GIT)
reduce friction and provide protective barrier from enzymes that are released into lumen. (Prevents autodigestion and absorption of toxic substances into bloodstream). Muscularis mucosa helps to move food along.
29
New cards
submucosa (GIT)
Absorption of nutrients from GIT into bloodstream, meissner's plexus helps coordinate peristalsis and absoprtion. Lymphatic tissue attacks foreign substances, destorys bacteria.
30
New cards
muscularis externa (GIT)
Peristalsis
31
New cards
Serosa
helps suspend gut in thoracic and abdominal cavities by attaching itself to surrounding structures, keeps everything in relative position.
32
New cards
seminal vesicle
secretes alkaline fluid rich in fructose and other nutrients. Useful to spermatozoa and neutralises acidity of vaginal tract, prolonging sperm life.
33
New cards
Elastic lamellae
dampens force of the heartbeat and causes blood to flow evenly
34
New cards
Endothelium
exchange of gases, hormones, nutrients and disposal of metabolic wastes. Reduces friction.
35
New cards
Valves
prevent backflow
36
New cards
Arterioles
control systemic blood pressure and local blood flow
37
New cards
Purkinje fibres
In myocardium. Generate nervous impusles and conduct them through myocardium. Synchronise heart beat. Are the conduction system of the heart.
38
New cards
chordae tendieneae
pull back on the valces to prevent them from bulging out towards the atria when the ventricles contract.
39
New cards
Lymphatic
returns interstitial fluid back into venous system to heart. Also carries away large particular matter such as large proteins which cannnot be absorbed through blood capillaries.
40
New cards
Vasa vasorum
Provide nourishment to adventitia and outer parts of tunica media of large vessels e.g. oxygen and glucose.
41
New cards
Nervi vasorum
Innervate smooth muscle of blood vessel
42
New cards
Tunica adventitia
anchor and protect the blood vessel. Also supply blood vessel itself with blood.
43
New cards
Trabeculae carnae
prevent suction, smooth blood flow, reduce turbulence for more efficient pumping of blood.
44
New cards
Reticular fibres
surround the sinusoid, supporting the endothelial cells
45
New cards
Respiratory epithelium
moisten and protect airway, barrier to pathogens and foreign particles by secreting mucous, removal of particulate matter by cilia
46
New cards
respiratory bronchiole
gas exchange across alveolar wall
47
New cards
olfactory glands (Bowman's)
serous secretion to moisten olfactory epithelium and to wash away previous volatile molecules to respond to changing smell stimuli
48
New cards
venous sinuses
warm and humidify nasal area
49
New cards
nasal conchae
filtration, heating and humidification of inhaled iar
produces surfactant. Crucial to function of neonatal lung, allowing alveoli to remain partially open (stabilises alveolus preventing collapse after exhalation). Decreases amount of energy needed to expand alveoli (since already partially open)
54
New cards
Macrophage (dust cell)
clean lungs of carbon and other dust-borne debris, invading bacteria, particulate matter etc.'
55
New cards
soft palate
closes of nasal passage when swallowing. When sneezing protects nasal passgage by divering a portion of mucus to mouth.
56
New cards
hard palate
provide firm, working surface for tongue. Helps speech and allows chewing while breathing.
57
New cards
vestibular fold
false vocal cord. Protect true vocal folds.
58
New cards
Epidermis
protection, cover, absorption of UV light for Vit. D, excretion via sweat glands, sensation (touch, pain, temperature), thermoregulation (blood radiation and sweat evaporation), UV protection via melanocytes
59
New cards
Stratum basale
mitotically active cells, replace the skin
60
New cards
Meissner's corpuscle
discriminative touch (mechanoreceptor)
61
New cards
Pacinian corpuscles
pressure and vibration receptor
62
New cards
Sebaceous gland
secrete sebum which assists skin texture and hair flexibility, some bactericidal and fungicidal agents
63
New cards
Arrector pili
contract and pull hair erect, when sympathetically stimulated
64
New cards
Nail matrix
proliferation of nail cells, nail grows longer
65
New cards
portal vein
supplies 75% of nutritious blood from GIT to liver
66
New cards
hepatic artery
supplies 25% of blood to liver
67
New cards
central vein
gets blood from hepatic sinusoids
68
New cards
Kupffer cells
liver macrophages
69
New cards
bile canaliculi
move bile manufactured by hepatocytes out to bile ductules to bile duct and out of liver via hepatic duct (into gallbladder)
70
New cards
gallbladder epithelium
resorbs water and concentrates bile
71
New cards
centroacinar cell
first cell of intercalated duct/duct system
72
New cards
zymogen granules
present in exocrine pancreas acini, contain enzyme precursors e.g. trypsinogen, chymotrypsinogen, peptidases, lipase, amylase
73
New cards
exocrine pancreas
make, store and release e.g. trypsinogen, amylase, maltase and lipase
74
New cards
endocrine pancreas
secretes hormones e.g. insulin and glucagon and somatostatin
75
New cards
alpha cells
of pancreas, periphery of islet, glucagon
76
New cards
beta cells
majority of pancreas, centre of islet, produce insulin
77
New cards
delta cells
make somatostain, decreases motility of GIT and gallbladder by affecting smooth muscle
78
New cards
von ebner's glands
serous salivary glands, also gustatory glands. Located near moat of foliate and circumvallate papillae, wash away debris for quick response in change of taste stimuli.
79
New cards
filiform papillae
provide a friction, rasplike surface that aids in holding food on tongue during chewing.
80
New cards
salivary glands
keep mucous membrane of mouth moist
81
New cards
Meissner's plexus
submucosal. Innervates muscle in muscularis mucosae.
82
New cards
Auerbach's plexus
myenteric. Innervates muscularis externa which is responsible for peristalsis.
83
New cards
Chief cells (of stomach)
zymogen granules, produce pepsinogen and lipase
84
New cards
parietal cells
produce HCL
85
New cards
lymph nodes
encapsulated lymphatic organs. Filters particulate matter, production of new lymphocytes (T&B)
86
New cards
Tonsils
incompletely encapsulated lymphoid nodules, do not filter lymph. Production of lymphocytes and controlling of pathogens.
87
New cards
rugae
allows stomach to expand and contract relatively rapidly
88
New cards
spleen
largest lymphoid organ. Destroys old RBC, proliferates T and B lymphocytes, removes particulate matter from blood, stores blood
89
New cards
white pulp
splenic nodules, have lymphocytes and macrophages organised around central artery.
90
New cards
thymus gland
organ of infancy and early childhood. Activates immature T cells that arrive from bone marrow, making them immunocompetent. Leaves T cells to go to lymph nodes and spleen.
91
New cards
thymic (Hassall's) corpuscle
produces cytokines
92
New cards
C cells
same as parafollicular cells (of thyroid)
93
New cards
Parafollicular cells
secrete calcitonin. Lowers blood calcium level by inhibiting bone resoprtion.
94
New cards
chief cells (of parathyroid)
secrete parathyroid hormone (PTH) which acts oppositely to calcitonin secreted by thyroid. i.e. it increases blood calcium level by stimulating bone resorption by osteoclasts
95
New cards
Oxyphil cells
of parathyroid (unknown function)
96
New cards
thyroid colloid
T3 and T4 hormones which control growth by affecting lipid and carbohydrate metabolism
97
New cards
Zona glomerulosa
(adrenal gland cortex) secretes mineralocorticoids e.g. aldosterone. Maintenance of fluid and electrolyte balance.
98
New cards
Zona fasciulata
(adrenal gland cortex) secretes glucorticoids just like zona reticularis. E.g. cortisol which is involved in lipid, protein and carbohydrate metabolism
99
New cards
zona reticularis
(adrenal gland cortex) secretes glucocorticoids just like zona fasciulata. E.g. corisol which is involved in lipid, protein and carbohydrate metabolism.
100
New cards
medulla
some cells of medulla produce adrenaline others produce noradrenaline.