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Covalent bond
When atoms share electrons
Ex: Hydrogen and Oxygen in H2O, Hydrogen and Oxygen share 2 atoms.
Valency
The number of electrions in an atom’s outer shell
Characteristics of CHON
96% of us
Carbon: acts as molecular glue because of 4 valence electrons- can bond in four different directions
Hydrogen: very reactive, hydrogen in = energy in, implies energy
Oxygen: oxygen in = energy out
Nitrogen: good for storing energy
Essential elements
Potassium, Iron, Calcium… (4% of us)
Ionic bonding
When a metallic atom gives an electron to a non-metal atom for a complete octet (8 valence electrons)
Saturated fats
A type of lipid with only single covalent bonds
Trace elements
Arsenic, Zinc… (0.0001% of us)
Unsaturated fats
A type of lipid with double covalent bonds
Hydrophobic
Doesn’t have affinity for water
Hydrophilic
Has affinity for water
Molarity
Molecules of solute per solution
Moles of solute divided by liters of solution
Emergent properties
Properties because of structure
Hydration shell
Water molecules surrounding a substance to form a shell around it
3 main properties of water
Cohesion: bonding between same molecules
Adhesion: bonding between different molecules
Surface tension: greater hydrogen bonds at the surface of water
Typers of isomers
Different bonds = structural isomer
Mirror image = enantiomers
Other = cis-trans isomer
Dehydration synthesis
Create covalent bonds (peptide bonds between amino acids in a protein) between molecules, where the reaction takes out H and OH from functional groups
Proteins
Proteins (made from peptide bonds)
Made up of amino acids which form a polypeptide
Primary structure: chain of amino acids, polypeptide
Secondary structure: alpha helix, beta sheet
Tertiary structure: 3D shapes where the different bonds of the R groups of amino acids determine form
Quaternary: proteins interacting with each other
Functions:
Enzymatic: catalyzed chemical reactions
Defensive: respond and act against invading pathogens
Storage
Hormonal: regulates the organism
Receptive: receives signals
Motor: movement
Structure
Carbohydrates
Carbohydrates (made from glycosidic linkages)
Properties: can dissolve water
Functions: storage of energy, production of energy, structure
Lipids
Lipids:
Triglyceroids
Properties: hydrophobic
Stucture: made up of glycerol and fatty acids
Function: store energy, transport fat for cell
Phospholipids
Structure: phosphate group, glycerol, fatty acids
Properties: phosphate head is hydrophillic and fatty acid tails are hydrophobic
Functions: stores energy, makes cell membrane
Steroids
Structure: 4 rings
Properties: hydrophobic
Functions: stores energy, helps with blood flow
Nucleic acid
DNA
Structure: double strands, nitrogenous bases (ACGT), sugar deoxyribose, directionality from 5’ to 3’
Function: storing hereditary information
RNA
Structure: single strands, nitrogenous bases (ACGU), sugar ribose, directionality from 5’ to 3’
Function
mRNA: translate information from DNA to ribosomes for protein synthesis
tRNA: link between mRNA molecule and growing chain of amino acids
rRNA: directs the catalytic steps of protein synthesis
How were cells formed
Elements formed lipids in water, which became more complex and became cell membranes
Endosymbiosos
Theory that organelles in eukaryotic cells are prokaryotic cells compartmentalized (inside). Two prokaryotic cells (archaebacteria, eubacteria) marged and formed eukaryotic cells
Cell theory
All living organisms are made up of cells and all cells originate from one cell
Nucleus
Has a nuclear envelope connected to ER. Stores chromosomes (chromatin- the entirety of genetic information stores in nucleus)
Ribosomes
Protein synthesis (not membrane-bound)
Golgi apparatus
Modifies proteins, synthsis of plysaccharides, releases stuff in vescicles
Lysosomes
Only in animal cells, sack of enzymes which break down macromolecules and damaged organelles, digestion
Central vacuole
Only in plant cells, for digestion, storage, wast disposal
Mitochondrion
Generates chemical energy, ATP to power the cell
Chloroplast
Only in plant cells, for photosynthesis
Cytoskeleton
Microfilaments, microtubules, intermediate filaments, helps support
Plasma membrane
Made mostly of phospholipids, some proteins and cholesterol, is selectively permeable
Endomembrane system
Vescicles bud off from ER
Vescicle fuses with golgi
Golgi modifies vescicular content
Vescicles bud off from golgi
Fuses with plasma membrane, or forms lysosome, which then fuses with endosome
Endoplasmic Reticulum
Smooth ER
Synthesis of lipids, metabolism of carbohydrates, stores calcium ions
Rough ER
Has ribosomes attached, aids in synthesis of proteins
Types of transport transmembrane methods
Ion channel
Passive transport
Gates which open and close to allow for diffusion
High concentration to low concentration
Sodium Potassium pump
Active transport
Sodium binds on protein which then releases it outside the cell
Outside cell, potassium binds on the proteins, which is then released inside cell
Energy to do this used from ATP hydrolysis (ATP = ADP + P, P used)
Proton pump
Active transport
Uses energy from ATP hydrolysis (ATP = ADP + P, P used) to move H+ inside the cell to outside the cell
From low concentration to high concentration
Cotransport
Facilitated diffusion
1st step, proton pump to move H+ out of cell
2nd step, H+ pulls sucrose into cell through a carrier protein
Exocytosis
Substance goes into cell, membrane forms around the substance and creates a vescicle
Endocytosis
Opposite of exocytosis, substance in vescicle moves out of cell, vescicles meges into plasma membrane
Metabolism
Change in energy
2 types of metabolism
Anabolism (A+B=AB)
Engergonic (requires energy)
Making molecules from smaller elements
Anabolic pathway - rises uphill - change in gibbs free energy is greater than 1
Catabolism (AB=A+B)
Exergonic (releases energy)
Breaks molecules down into smaller elements
Catabolic pathway - falls downhill - change in gibbs free energy is smaller than 1
Energy coupling
Usage of energy from one chemical reaction power to another: the energy produced by one reaction powers another
Enzymes
Biological catalysts, speeds up chemical reactions, reusable
Affected by pH, temperature, salinity = causes protein to change shape
Denature
Enzyme that has difficulty working because of shape change
Renature
Return to original shape of enzyme
Enzyme Substrate Complex
Active site: where the substrate binds
Allosteric: outside the active site of enzyme
Inducer: molecules that can also bind to an enzyme, can be competitive and non-competitive
Activation energy
Energy needed to start a reaction
Word endings
OSE - carbohydrate
ASE - enzyme
IN - protein
Null hypothesis
Variables do not cause each other
Alternate hypothesis
Variables cause each other
Proof of evolution
Homology (ancestral, analogous structures)
Cladistics / molecular biology
Fossil record
Biogeography
Embryonic development (resembes “mini-evolution”)
Ancestral structures
Homologous structures as a result of divergent evolution
Ex: black bears and pandas having round ears
Analogous structures
Homologous structures as a result of convergent evolution
Ex: bats and birds having wings
Convergent evolution
Two different species that develop similar traits due to their environment or other pressures
Ex: dolphins and fish looking similar because of onvironmental pressure of the water
Divergent evolution
When a species have similar traits because they have a common ancestor with those traits
Ex: chimpanzees and humans looking alike because of a common ancestor
Homologous
Having similar / the same structures or characteristics
Cladistics
The study of genetics
Cladogram
Diagram that shows the genetic relationships between organisms
Four steps of evolution
Overproduction
Struggle to survive
Variation
Reproduction
Philogenetic tree
A diagram that represents evolutionary relationships between organisms
Punctuated equilibrium
Features in a species quickly changing
Ex: moths turning black due to pollution in trees
Graduation
Slow, uniform, and gradual speciation / changing features
Ex: chimpanzees slowly starting to walk and become humans
Intermittent species
All of the soecies in between the evolution of one species into another
Hardy-Weinberg formulas
Microevolution
Changing small feature of a species, no speciation happening
Ex: blue eyed group of humans becoming black eyed
Macroevolution
A species becoming another, speciation
Ex: chimpanzees becoming humans
Linnaean classification system
Domain (Eukarya), Kingdom (Animalia), Phylum (Chordata), Class (Mammalia), Order (Primates), Family (Great Apes), Genus (Homo), Species (Sapien)
Paraphyletic
Some organisms from one group and some from another
Ex: fish with pink flesh
Monophyletic
All the organisms of a group
Ex: Mammals
Polypheletic
All the organisms of multiple groups
Ex: Insects and spiders
Taxonomy
Putting things into groups; classification
Clade
A node point and all of its descendents on a cladogram
Derived structure
A structure that an organism has as a result of diverence from another species
Ex: having five fingers is a derived structure of primates
Homoplasy
Used to do the same thing
Ex: bird wings and bat wings
Non-homoplasy
Not used to do the same thing
Ex: penguin wings and seagull wings
Types of selection
Niche
A job that a specific organism does; role or function of an organism in their ecosystem
Ex: a graden spider’s niche is to hunt prey in plants
Adaptive radiation
An event in which a lineage rapidly diversifies with multiple new lineages evolving different adaptations. Usually happens after periods of mass extinction, where new niches have to be filled and there are new opportunities for evolution
Ex: mammals after the extinction of dinosaurs
Cline
A slope
The domains of life
Eukaryotes
Eubacteria
Archaebacteria
Eubacteria and Archaebacteria are more closely related to Eukaryotes than with themselves, which suggests the theory of endosymbiosis is true
The story of Darwin’s finches
An example of adaptive radiation. Their common ancestor arrived to the Galapagos around 2 mya. During the time that has passed, Darwin’s finches have evolved into 18 different species with different characteristics and structures due to the environmental conditions of each island. The islands are also geographically isolated, which prevented genetic information flowing between the archipelago. This is also an example of natural selection
What is cellular respiration
A metabolic pathway that uses glucose to produce adenosine triphosphate (ATP)
Where do the 4 stages of cellular respiration occur
Glycolisis: in the cytoplasm of the cell
Pyruvate oxydation: starts outside of the mitochondria, then inside the mitochondria
Citric acid cycle (Kreb’s cycle): in the mitochondrial matric
Oxidative phosphorylation: inner mitochondrial membrane and intermembrane space
Aerobic
With oxygen- in cellular respiration, allows for procession into Kreb’s cycle
Anaerobic
Without oxygen- in cellular respiration, Kreb’s cycle will not happen
Glycolysis
Investment phase
Turns glucose into two G3P
Process uses two ATP (turns into two ADP)
Payoff phase
Turns two G3P into two Pyruvate
Process uses NAD+ (turns into NADH) and two ADP (turns into two ATP) for each G3P turned into Pyruvate
Pyruvate oxydation
Pyruvate is turned into Acetyl COA
Process uses O2 (turns into CO2) and NAD+ (turns into NADH)
Acetyl is transported into the mitochondria by the coenzyme A (COA)
Citric acid cycle (Kreb’s cycle)
Acetyl COA is turned into Oxaloacetote, which helps turn Acetyl COA into Oxaloacetote (reason why it’s a cycle)
COA leaves the Acetyl once it arrives in the mitochondria
Process uses NAD+ (turns into NADH), GDP+P (turns into GTP which then turns into ATP), and FAD (turns into FADH2)
Another product of the process is CO2
Oxydative phosphorylation
Uses NADH+H+, and 2H+ to pump protons into the intermembrane system
This causes the intermembrane space to have a high concentration of H+
H2 from FADH2 (which turns into FAD) and ½O2 is turned into H2O
H+ from the intermembrane space can only escape through ATP synthase, which causes a turbine to turn, which in turn synthesizes ADP and P into ATP
Conclusion: uses products of the other phases of cellular respiration to synthesize ATP
Photosynthesis
Happens in chloroplast
The conversion process that transforms the energy from the sunlight into chemical energy stored in sugars and other organic molecules
Hypotonic
Solutions having lower osmotic pressure (lower solute concentration and higher water concentration)
A hypotonic red blood cell will shrink because of this
Hypertonic
Solutions having higher osmotic pressure (higher solute concentration and lower water concentration)
A hypertonic red blood cell will expand because of this
Isotonic
Solutions having equal osmotic pressure
Osmosis
The movement of molecules of solute through a selectively permeable membrane from a region of low solute concentration to a region of high solute concentration
Water moving from high concentration to low concentration
The amount of solute in water decreases its concentration
Autotrophs
Organisms that can produce their own energy without having to consume other organisms
Ex: plants
Heterotrophs
Organisms that cannot produce their own energy, so they have to consume other organisms in order to get their energy
Ex: humans
What are the components of Chloroplast
Outer membrane
Inner membrane
Stroma: fluid inside the chloroplast
Thylakoid: disc-like structures in the chloroplast
Granum: a column of thylakoids stacked on each other
Lumen: thing inside the thylakoid
Where do light reactions happen
Inside the thylakoid and along its membrane
Carbon fixation
Biological process where carbon dioxide from the environment is converted into a biological compound
Phosphorylation
Attaching a phosphate group to an ion or molecule
Photosynthesis in thylakoid
Light reactions and water cause electrons to move across the thylakoid membrane and to help the synthesis of NADPH
The high proton concentration from the breakup of H2O in the Thylakoid causes H+ to move through the ATP synthase, which synthesizes ATP
ATP and NADPH is then used in the Calvin cycle
Calvin cycle
Happens in the stroma after photosynthesis in thylakoid
Takes CO2 from the atmosphere and utilizes the ATP and NADPH generated from photosynthesis in thylakoid to generate G3P which is used to synthesize glucose
The entire process recycles the molecules and repeats over and over again
Absorption spectrum
If you wear a green shirt, the shirt is absorbing
This means that whatever an object’s color is, it is reflecting that color, while absorbing all of the others
Signal
Sending information to other cells or components