record of electrical activity of the heart in the myocardium
electrocardiogram
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ECG name
electrocardiogram
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what is this
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what is this
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what is this
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what is this
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what does the p wave show?
depolarization of the atria
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what does the qrs complex show
ventricular depolarization and atrial repolarization
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how long is the qrs complex
0.11 seconds
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what does the t wave show
ventricular repolarization
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how long is the pr interval?
0.16 seconds
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how long is the qt interval
0.36 seconds
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what 2 things happen during the pq interval?
1) atria contract and then begin to relax 2) ventricles begin to contract
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what happens during the qt interval?
ventricles contract and begin to relax
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what is this
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what is this
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what is this
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what is this
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what is this
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what are the two parts of the cardiac cycle
1) systole 2) diastole
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what is the hearts contracting faze
systole
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what is the hearts dilating faze
diastole
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what are the 2 periods of systole
1) period of isovolumetric contraction 2) period of ejection
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what are the 3 periods of diasole
1) period of isovolumetric relaxation 2) passive ventricular filling 3) active ventricular filling
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blood flows from _______ to _______ pressure
higher;lower
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contraction ________ pressure
increases
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av valve is closed when ventricle pressure is _______ than atrial pressure
greater
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pulmonary and aortic semilunar valves are closed when semilunar pressure is ___________ than ventricle pressure
greater
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volume of blood in ventricles at end of diastole
end diastolic volume
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what is the amount of blood left at end diastolic volume
120-130 ml
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what are the two pressures of the ventricles during period of ejection
left ventricle= 120 mmhg right ventricle= 25 mmhg
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what is the end systolic volume
50-60 ml
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amount of blood remaining in a ventricle after contraction
end systolic volume
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passive ventricular filling accounts for ____% of ventricular filling
70
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During isovolumetric contraction, the pressure in the ventricles is _________ than the pressure in pulmonary trunk/aorta pressure
lower
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when does the first heart sound occur?
during the phase of isovolumetric contraction
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what causes the first heart sound
closure of AV valves
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when does the second heart sound occur
ventricular diastole
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what causes the second heart sound
closure of semilunar valves
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when does the third heart sound occur
early diastole
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what causes the third heart sound
Turbulent blood flow into ventricles
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what does MAP stand for
mean arterial pressure
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MAP equation
MAP= CO x PR
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what does CO stand for
cardiac output
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what does PR stand for
peripheral resistance
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what is PR
total resistance against which blood must be pumped
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what is CO
the amount of blood pumped by heart per minute
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what is SV
blood pumped during each heart beat
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what is HR
number of times heart beats per minute
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CO equation
CO = HR x SV
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What is the cardiac reserve
difference between resting and maximal CO
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what is the hearts intrinsic regulation
normal functional characteristics of the heart that regulate it
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what is the preload
the degree of stretch on the heart before it contracts
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what effects preload
venous return and end systolic pressure
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what is venous return
amount of blood returning to the heart from systolic circulation
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what is afterload
pressure the contracting ventricles must produce to overcome the pressure in the aorta and move blood into the aorta
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what are the two stimulators of parasympathetic extrinsic regulation
1) vagus nerve 2) actylecholine
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what does the vagus nerve do?
decreased the rate of the SA node and slows impulse conduction of the AV node
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what does acetylcholine do to the heart
decreases SV and HR by binding to membrane to make more permeable to potassium therefore hyperpolarizing the heart
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what are the two stimulators of sympathetic division of extrinsic regulation
1) cardiac nerves 2) epinephrine and norepinephrine
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what does the cardiac nerves do to herat
increases heart rate and force of contraction
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higher heart beat = _______ cardiac output
higher
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where does epinephrine and norpinephrine come from
adrenal medulla
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what senses the change in blood pressure
baroreceptors
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where is baroreceptors located
in walls of internal carotids and aorta
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Where does the baroreceptor signal change in?
parasympathetic and sympathetic divisions
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what senses change in ph, co2 and o2
chemoreceptors
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where is chemoreceptors located
medulla oblongata
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where does chemoreceptors measure o2
aorta and internal carotids
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if blood PH increases, the sa node and cardiac muscle would ________ activity
decrease
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if blood ph decreases, the sa node and cardiac muscle would _________ activity
increase
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Increase in Extracellular Potassium (K+)
Causes a Depolarization (more positive) increases heart rate
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decrease extracellular K+
hyperpolarization-- decreases heart rate
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increase in calcium would
reduce heart rate
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increase in body temperature would ________ HR
increase
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decrease in body temp would ________ HR
decrease
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what is the baroreceptor reflex
Autonomic response to changes in blood pressure detected by baroreceptors in the carotid artery and aortic arch. Increases in blood pressure activate the baroreceptors which result in inhibition of sympathetic input to the heart and vasculature and activation of vagal input to the heart resulting in decreased blood pressure. Decreases in blood pressure result in activation of sympathetic input to the heart and vasculature and inhibition of vagal input to the heart.
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what is the chemoreceptor reflex
chemoreceptors monitor chemical composition of blood
increased sympathetic impulses increase BP to drive gas exchange through the lungs
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what are the two places chemoreceptors are
1) medulla oblongata 2) carotid body
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what are the two places baroreceptors are
1) internal wall of carotid artery 2) aorta
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what nerve does the parasympathetic nerve fibers effect
vagus nerves
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what nerves does the sympathetic nerve fibers effect
cardiac nerves
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what gland does the sympathetic nerve fibers effect
adrenal gland
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where is epinephrine and norepinephrine produced
adrenal medulla
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what is endocarditis
inflammation of the endocardium
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what is myocarditis
inflammation of the myocardium
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what is pericarditis
Inflammation of the pericardium which is usually idiopathic or viral (90%). Other causes include bacterial, autoimmune, connective tissue disease, neoplasm, radiation, chemo, drug toxicity, cardiac surgery, or myxedema. MC in men and
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what is angina pectoris
chest pain caused by inadequate flow of blood and oxygen to the heart
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what is a characteristic of angina pectoris
narrowed and hardened adrenal walls
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what is given to patients with angina pectoris
nitroglycerin
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what is coronary thrombosis
formation of a blood clot in a coronary artery
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what is myocardial infarcation
prolonged lack of blood flow which causes lack of oxygen which results in cellular death