Exam 3

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Microbial toxins commonly found In foods include
* mycotoxins (fungi)
* Scombroïd histamine - producing

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True or false: fungal spores are easily spread due to their small size
True
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Mycotoxins are _ produced by
Toxic substances; some fungi
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What three mycotoxins may be found in food?

1. Aflatoxin
2. Ergot
3. Intestinal irritants
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Intestinal irritants are produced by
Poisonous mushrooms
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Aspergillus flavus produces a toxin called _ which causes an
Aflatoxin;intoxication
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What toxin is found in moldy grains and nuts, including peanuts and soy?
Aflatoxin
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Aflatoxin can cause _ and is often
Severe liver damage, including cirrhosis, necrosis, and carcinoma - is often fatal
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In 2013, what product was recalled due to a aflatoxin contamination?
Dog foods (due to contaminated corn)
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In the U.S., we test foods for what toxin?
Aflatoxin
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True or false: human cases of aflatoxin are common
False
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What toxin is produced by the fungus Claviceps purpureathat infects rye?
Ergot
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Ergot causes a syndrome known as ergotism or "St. Vitus dance”which causes what two symptoms?
Spasms and hallucinations
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The strange symptoms

In Salem were actually due to which toxin?
Ergot
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In a 2012 outbreak,a caregiver accidentally used what to make soup for elderly patients?
Poisonous mushrooms
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Scombroid poisoning is an intoxication that is caused by
Ingesting large amounts of histamine
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Scombroid poisoning usually results from fish being
Held at high temperatures for long periods of time
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The scombroid toxin is
Heat - stable
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Severe cases of scombroid may require treatment with
fast acting antihistamines
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What food was common in scombroid outbreaks?
Imported tuna
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True or false: algae rarely causes disease
True
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Most algae-cases are due to what two types of toxins?

1. Ciguatoxin
2. Paralytic shellfish poisoning(PSP)
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How can you prevent being infected with ciguatoxin?
Eat smaller fish
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Human cases of ciguatera usually occur after the ingestion of what types of fish?
Barracuda, snapper, jack and grouper
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Shellfish toxins are caused by several types of _ including the species that causes
Algae; red tide
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True or false: shellfish toxins can be destroyed by cooking
False they're heat stable
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True or false: symptoms of shellfish toxins can be confused with shellfish allergies
True
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In severe cases, shellfish toxins can cause
Muscle paralysis and respiratory failure
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In what climate does most PSP cases occur?
Colder climates
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What is the most common PSP toxin?
Saxotoxin
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For PSP, death can occur within _ due to what symptom?
3 to 4 hours due to respiratory paralysis
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Amnesiac shellfish poisoning is caused by
Dominic acid, a toxin produced by algae
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How are environmental toxins released?
Industrial processes can release contaminates into the environment
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What 3 contamination paths can result in contaminated produce, dairy, meats, and seafood?
Polluted air, water, and soil
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Persistence of toxins refers to
The extent to which the toxin lingers in the environment or in the body
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Contaminants present for a short time or eliminated by the body pose
Little health risk
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Contaminants which persist may also
Bioaccumulate
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True or false: some toxins do not breakdown in the environment
True
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If the toxins don't break down in the environment, they move up through the _ and
The food chain; accumulate
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Exposure to _ results in impaired
Methylmercury; neurological development in the fetus
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Mercury is used in many pharmaceuticals as a
Preservative
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Mercury is added to multi-use vials to prevent
The growth of microorganisms
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PCB are _ that were used in hundreds of industrial and commercial applications
Chlorinated hydrocarbons
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PCBs are known to cause cancer in
Animals
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PCBs were banned in the US but they do not breakdown and can be found

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-In the environment

\-In wildlife tissues

* In the food chain
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PCBs exert toxic effects on the following four body systems

1. Immune system
2. Endocrine system
3. Reproductive system
4. Nervous system
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Dioxins and furans refers to
A family of toxic substances that have similar chemical structures
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Dioxins and furans are the by products of industrial processes or are created during burning
Waste and wood
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What foods are dioxins and furans found in due to accumulation in environment?
Meat and dairy
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Five health effects of dioxins and furans

1. Chloracne and other skin conditions
2. Immune system damage
3. Developmental damage
4. Reproductive damage
5. Cancer
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In 1968 in Japan, a number of patients were reported to have symptoms including acne-like eruptions, pigmentation of the skin, and eye discharge. What disease was this? What was the cause?

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Yusho disease caused by vice oil that was contaminated with dioxin-related compounds
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True or false: A number of plants contain natural toxins
True
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Natural toxins in plants are designed to
Protect the plants from insect damage
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True or false: natural toxins found in plants are harmful in small amounts
False
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What are the three most common toxins found in plants?

1. Goitrogens
2. Cyanogens
3. Solanine

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Goitrogens can cause enlargement of the thyroid gland by
Blocking the uptake
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Some foods contain cyanogens which can convert to
Cyanide
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What disease is a neuromotor disease caused by exposure to cyanogen poisons in cassava?
Konzo disease
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Kong disease occurs when cassava is
Not processed properly to break down the cyanogens
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True or false: Laetrile derived from apricot pits cure cancer
False
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Which natural toxin is a narcotic-like poison found in potatoes?

A. Goitrogens

B. Cyanogens

C. Solanine
c. Solanine
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Solanine poisoning is rare except in times of
Food shortage
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What are the two main environmental impacts of pesticides?

1. Runoff contaminates water sources
2. Large amounts of fuel involved in production
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Pesticides are chemicals used to kill the following 4 groups:
1. insects


2. weeds
3. Fungi
4. Other such as rats, birds, etc.

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What are the 4 advantages of pesticides?

1. Large scale food production
2. Protection from insect-born diseases
3. Economic growth- cotton, flowers, etc.
4. Reducing and eliminating mosquito, ant, and cockroach populations
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A growing population requires an ever
Increasing amount of food
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The introduction of pests could quickly overwhelm large scale productions without the use of
Pesticides
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True or false: pesticides are used in organic farming
True it's the synthetic pesticides that aren't allowed
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What can help prevent the spread of mosquito-borne diseases such as malaria?
Bed nets treated with insecticides
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Crops protected contribute how much to the economy in Florida?

A. $30 million

B. $4000

C. $100 billion

D. $10 billion
D. $10 billion
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What are the 3 main disadvantages of pesticides?

1. Potential negative effects on the environment
2. Potential negative effects on humans
3. Misuse
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What is an example of a potential negative effect on the environment due to pesticides?
Harming non-target species
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What is an example of a potential negative effect on humans due to pesticides?
Developmental problems in children
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What are two examples of misuse of pesticides?

1. Overuse in areas where pesticides are cheap
2. Suicides
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Malathion breaks down in the environment with exposure to what two things?
Sunlight and water
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What pesticide is used in the trucks that spray for mosquitos?
Malathion
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Columbia university scientists found that infants with high exposure to chlorpyrifos had
Lower birth rates and birth lengths
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An MRI revealed that high exposure to chlorpyrifos in infants could possibly lead to what following altered development in the brain?
Lower IQs and attention disorders
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Use of pesticides increased due to
Marketing and misunderstandings
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Farmers were challenged to reduce pesticide use and saw_ in yield and what in costs?
Increases; decreases
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How many people worldwide commit suicide annually?

A.2 million

B. 3 million

C. 1 million

D. 500,000
c. 1 million
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What is the leading cause of suicide? What fraction of cases can it be linked to?
Ingestion of pesticides; one-third
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What are the three routes of exposure for pesticide?

1. Ingested
2. Aerosol
3. Contact
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Pesticides can cause what 3 health problems?

1. Birth defects
2. Nerve damage
3. Cancer
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True or false: The effects depend on how toxic the pesticide is and how much of it is consumed
True
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Food and water are vulnerable to pesticide contamination from the intentional or unintentional use of these chemicals in what three places?

1. Agriculture
2. Retail
3. In the home
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True or false: pesticides don't leave any residue in the environment and on some of the foods we eat
False
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What are the 5 ways foods can come into contact with pesticides considering the farm to fork approach?

1. Field
2. Transport
3. Packing
4. Grocery
5. Home

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International science- based standards are set by a joint committee (2)
FAO (Food and agricultural organization of the united nations) and WHO (World Health Organization)
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The maximum pesticide residue in a specific crop grown with recognized good agricultural practices that is expected not to cause harm to human health from consumption
Maximum residue limit (mrl)
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An estimate of the amount of pesticide residue that can be ingested daily over a lifetime without appreciable health risk
Acceptable Daily intake (adi)
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Which organization:

* establishes a tolerance level for pesticides in foods
* Establishes which pesticides can be used for which crops
* Regulate misuse of pesticides, resulting in fines, lawsuits, and destruction of crops
* Evaluates pesticides to ensure they will not harm people, non-target organisms, or the environment

A. FDA

B. EPA

C. WHO

D. MRL
B. EPA
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True or false: In recent years, the number of foods exceeding the EPA pesticide tolerance levels have increased but remain below 1% of all foods tested
True
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What organization enforces tolerance levels set by the EPA by monitoring foods and livestock feeds for the presence of pesticides?

A. FDA

B. EPA

C. WHO

D. Not enforced
A. FDA
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True or false: FDA can test foods produced domestically and imported
True
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True or false: The FDA cannot force companies, exporters, etc., to test at their own expense and provide certifications
False
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What is the "dirty dozen” list that is released each by the EWG?
A list of foods which are suspected to contain the greatest amount of residue
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What factor is usually missing from EWG dirty dozen list?
Is there an effect on health due to the pesticides found on the dirty dozen?
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The pesticides detected on the dirty dozen were at such _ levels that they posed what amount of risk to the consumer?
Low; no risk
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The substitution of organic foods in the dirty dozen resulted in
No appreciable reduction of consumer risk