Transport food, water, electrolytes, enzymes, hormones, antibodies, oxygen to cells of the body and remove wastes and carbon dioxide
Function of the Cardiovascular system
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Apex
Inferior margin is pointed
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Base
Superior margin is flattened
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Pericardium
Triple layered sac that surrounds and protects the heart. It confines the heart to its position in the mediastinum, yet allows it sufficient freedom of movement for vigorous and rapid contraction
Thinner membrane that forms a double layer (parietal + visceral) around the heart
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Parietal Pericardium
Outer layer of the serous pericardium that is fused to the fibrous pericardium
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Visceral pericardium (epicardium)
Adheres directly to the heart and is composed of squamous epithelium
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Pericardial Cavity
Space between the parietal pericardium and the visceral pericardium filled with fluid that acts as a lubricant to prevent friction when the heart beats
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Epicardium
Outer layer of the heart wall
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Myocardium
Thickest, middle layer of the heart. Cardiac muscle; Cardiac muscle cells are arranged in spiral bundles.
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Endocardium
Inner layer of heart wall composed of squamous epithelium and lines the chambers of the heart and covers the heart valves
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Atria
(right and left) Superior and smaller chambers of the heart that act as receiving chambers for blood entering the heart. Myocardium is thin
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Left atrium
Collects blood from the four pulmonary veins which drain blood from the lungs
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Right atrium
Collects blood from the superior vena cava, inferior vena cava and coronary sinus, superior vena cava drains blood from the body above the heart, inferior vena cava drains blood from the body below the heart, coronary sinus drains blood from the heart itself
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Auricles
Earlike appendages attached to the atria that increase the internal volume of the atria as they receive blood
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Interatrial septum
Right and left atria are separated by a wall
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Ventricles
(right and left) The inferior and larger chambers of the heart that push blood out of the heart and into the blood vessels.
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Right ventricle
Pumps blood into the pulmonary trunk which carries the blood to the lungs
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Left ventricle
Pumps blood into the aorta which carries the blood to the body
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Left
Myocardium is thick in which ventricle having the thickest heart wall?
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Trabeculae carneae
Inner wall has irregular folds of muscle
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Papillary muscle
Trabeculae carneae form slender projections which attach to the heart valves.
Attaches from the cusps of the AV valves (prevent them from turning inside out), to the papillary muscles on the ventricular walls
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Heart Murmur
AV valves have a defect that prevents complete closure, some blood flows back into the atria
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Pulmonary valve
Between the right ventricle and the pulmonary trunk
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Aortic valve
Between the left ventricle and the aorta
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Lub
Sound from the closing of the tricuspid and bicuspid valves and the contraction of the ventricles
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Dup
Sound is the closing of the aortic and pulmonary valves
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Coronary circulation
Flow of blood to the heart
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Coronary arteries
Branch into more arteries forming a crown or corona around the heart
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Corona
A crown around the heart
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Cardiac Cycle
Sequence of events that occurs during one heartbeat, 72 bpm means a cardiac cycle of .8 seconds
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Systole
Ventricles contracting
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Diastole
Ventricles relaxing
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Sinoatrial (SA) node
Heartbeat originates in the heart muscle itself, certain cardiac muscle cells repeatedly fire spontaneous action potentials (impulses) that then trigger heart contractions
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Atrioventricular (AV) node
Where the Action Potential spreads from SA node that's located in the septum between the two atria
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Step 1 of Heart Conduction System
SA node triggers action potential (AP) which spreads over the muscle fibers and causes both the left and right atrium to contract
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Step 2 of Heart Conduction System
Action Potential spreads from SA node to the atrioventricular (AV) node, located in the septum between the two atria.
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Step 3 of Heart Conduction System
AP enters the Atrioventricular node bundle (bundle of His), the only connection between the Atria and Ventricles.
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Step 4 of Heart Conduction System
AP travels down the bundle of His where it splits into Right and Left bundle branches, towards the apex of the heart.
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Electrocardiogram (ECG or EKG)
Can be used to see electrical activity of the heart
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P wave
Electrical wave passes over atria
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Q, R, S waves
Electrical wave passes over ventricles
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T wave
Repolarization of the ventricles
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Purkinje fibers
Conduction myofibers rapidly conduct the AP from the apex upward to the remainder of the ventricular myocardium
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Arrhythmia
Abnormal Heart Rhythms
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Tachycardia
Heart beats too rapidly (over 100 bpm)
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Bradycardia
Slow heart beat (under 60 bpm)
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Fibrillation
Small areas of heart beat weakly and independently of each other, no blood is pumped
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Inferior and Superior VC --\> Right atrium --\> Tricuspid valve --\> Right ventricle --\> Pulmonary semilunar --\> Pulmonary artery --\> Lungs --\> Pulmonary vein --\> Left atrium --\> Mitral (Bicuspid) valve --\> Left ventricle --\> Aortic semilunar --\> Aorta --\> Arteries --\> Capillaries --\> Veins
Full blood flow through the heart
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Stroke volume
Amount of blood pumped by the left ventricle
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Cardiac Output \= heart rate * stroke volume
Cardiac Output equation
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Medulla oblongata
Regulates Heart rate or number of heartbeats per minute and is connected to the heart by autonomic nerves
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Sympathetic division
Contains cardioaccelerator nerves that increase the heart rate
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Bainbridge reflex
These nerves increase heart rate during physical activity
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Starling's law (of the heart)
The stretching of cardiac cells by blood will increase the strength of the contraction
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Arteries
Blood vessel that carries blood away from a heart chamber
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Tunica intima
Lining of endothelium covered by connective tissue rich in elastic fibers, creates a hollow interior or lumen
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Tunica media
Middle, thick layer of smooth muscle and elastic fibers
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Tunica adventitia
Outer layer of connective tissue that anchors the artery to neighboring structures
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Capillary
Microscopic vessel that connects the arterioles and venules
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Capillaries
Permits the exchange of nutrients and gases between the blood and interstitial fluid
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Diffusion, osmosis, facilitated diffusion, active transport
Name processes that capillaries use to regulate the movement of materials
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Endothelium (Capillaries)
The semi-permeable and regulates the movement of materials by the processes of diffusion, osmosis, facilitated diffusion and active transport
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Veins
Blood vessel that carries blood toward a heart chamber
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Tunica intima
Thin layer of endothelium, larger lumen than an artery
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Tunica media
Thin layer of smooth muscle, properties of contractility and elasticity are limited
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Tunica adventitia
Thickest layer of connective tissue
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Distensibility
When the vein fills with blood it expands
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Valves, Respiratory pump, Skeletal muscle pump
Venous Return of blood to the heart
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Pulse
Expanding and recoiling of an artery wall felt at points where arteries are superficial and lie over firm structures
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Increase
Epinephrine and norephinephrine \___________ blood pressure