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Tissue
A group of similar cells that perform the same function.
Histology
study of tissues
What are the four types of tissues?
epithelial, connective, muscle, nervous
epithelial tissue
Sheets of tightly packed cells that line organs, body cavities, and body surface. Also known as epithelium.
What are two forms of epithelial tissues?
covering and lining epithelia, glandular epithelia
What is glandular epithelium?
secretory tissue in glands
Example of glandular epithelium
salivary glands
What is the covering and lining epithelia?
on external and internal surfaces
Example of covering/lining type of epithelium
skin
Main Functions of epithelial tissues
protection, absorption, filtration, excretion, secretion, sensory reception
Structural features of epithelial tissue
Polarity, Specialized Contacts, Supported by Connective Tissues, regenerative, avascular but innervated
What are the specialized Contacts in the epithelial tissue?
Tight junctions, desmosomes, gap junctions
What is a tight junction?
Prevents substances from leaking across epithelial layer? It is like sewing
What is a desmosome?
Prevents adjacent cells from pulling apart. Ex. Velcro straps
What are gap junctions?
Small tunnels that connect cells, facilitating the movement of small molecules and ions between the cells.
What is polarity in the epithelial tissue?
apical surface and basal surface
What are apical surfaces?
Borders open space; smooth
What is the basal surface?
attached to the underlying basal laminate and next to the underlying connective tissue
What does the basement membrane consist of?
basal lamina and reticular lamina
What is the basement membrane?
Connective tissue reinforcing all epithelial sheets. It resists stretching and tearing.
Why is it so dangerous for epithelial cells to break through the basement membrane?
Breaking through basement membrane is a feature of skin cancers
What is avascular
no blood vessels
How is the epithelial tissue nourished?
by diffusion from underlying connective tissues
What is innervated
supplied by nerve fibers
Two types of layers in epithelia
Simple and stratified
What is a simple layer
single layer of epithelial cells
What is a stratified layer?
multiple layers of epithelial cells
What are the three types of epithelial cells?
squamous, cuboidal, columnar
What is the function of simple squamous epithelium?
Allows materials to pass by diffusion and filtration sites
What is the second function of simple squamous epithelium
Secretes lubricating substances in serosae
Where is simple squamous epithelium found?
lungs, kidneys, blood vessels, and lymphatic vessels, serosae
What does simple squamous epithelium look like?
single layer of flat cells
What does the simple columnar epithelium look like?
Single layer of tall cells
What is the function of simple columnar epithelium?
Absorption, secretion of mucus, cilia to move substances over epithelial surface
Where is simple columnar epithelium found?
digestive tract, gallbladder, ducts of some glands, bronchi, and uterine tubes
What does the pseudostratified columnar epithelium look like?
Single layer of cells of different heights, some not reaching free surfaces
What does the pseudostratified columnar do?
Mucus secretion, movement of mucus by sweeping action of cilia on apical surface
Where is the pseudostratified columnar epithelium found?
Upper respiratory tract, ducts of large glands, and tubules in testes
What does the Stratified squamous epithelium look like?
Thick epithelium composed of several cell layers. Apical surface is squamous, deeper layers are often cuboidal or columnar
What is the stratified squamous epithelium function?
Protects underlying tissues in areas with lots of wear-and-tear
Where is the stratified squamous epithelium located?
Near keratinized areas in the skin and in non-keratinized areas in moist linings like back of the throat.
Which classes of the epithelia are very rare?
Stratified cuboidal and stratified columnar epithelium
What is the stratified cuboidal epithelium
Function: protection Location: Largest ducts of sweat glands, mammary glands, and salivary glands.
What is the stratified columnar epithelium
Function: protection and secretion Location: rare in the body; small amounts in male urethra and in large ducts of some glands
Where is transitional epithelium found?
lines the ureters, urinary bladder, and part of the urethra
What does the transitional epithelium look like?
resembles both stratified squamous and stratified cuboidal; basal cells cuboidal or columnar; surface cells dome shaped or squamous-like, depending on degree of organ stretch
What does the transitional epithelium do?
allows the urinary organs to expand and stretch; cells change shape when stretched
What is a gland?
One or more cells that makes and secretes an aqueous fluid called a secretion
What is glandular epithelium?
composed of cells that produce and secrete substances into ducts or body fluids
What is the multicellular epithelial gland?
Form by inward growth of an epithelial sheet.
What are the two types of glands?
exocrine glands and endocrine glands
What does the exocrine gland do?
secretes substances (oil, saliva, sweat) into ducts (tiny tube) then the substance will empty onto the body surface or into an opening inside the body (lumen)
Example: oil glands of skin, Salivary glands, mucus, oil, sweat
What does the endocrine gland do?
secrete hormones into tissue fluid or blood
Example: adrenal glands, ovaries, testes
What is muscle tissue?
Tissue that has the ability to contract or shorten. Voluntary muscle (skeletal) and involuntary muscle (smooth muscle and cardiac muscle). Responsible for body movements
Three muscle types?
skeletal, cardiac, smooth
What does the skeletal muscle look like?
long, cylindrical, multinucleate cells; obvious striations;multiple nuclei per cell
What does the skeletal muscle do?
It produces voluntary movement
Where is the skeletal muscle located?
attached to bones and skin
What does the cardiac muscle look like?
Branched cells, obvious striations, 1-2 nuclei per cell
What does the cardiac muscle do?
Contracting heart & propelling blood; involuntary movements
Where is cardiac muscle located?
heart
What does the smooth muscle look like?
Cells are spindle shaped, no striations, cells arranged closely to form sheets
What does the smooth muscle do?
Propels substances or objects along internal passageways; involuntary control
Example: urine, baby, foodstuffs
Where is smooth muscle located?
blood vessel walls and walls of hollow organs
What is the nervous tissue?
main component of the nervous system, helps regulate and control body functions
Where is nervous tissue found?
brain, spinal cord, nerves
Which tissues regenerates poorly?
Cardiac muscle and nervous tissue
Which tissues regenerate a moderate amount?
Smooth muscle and dense regular connective tissue
Which tissues regenerate easily?
Bone, epithelia, dense irregular connective tissue, blood-forming tissue, areolar connective tissue
What is the cutaneous membrane?
The skin, a dry membrane with a keratinizing epithelium (the epidermis).
What are the two layers of the cutaneous membrane?
Epidermis: keratinized stratified squamous epithelium
Dermis: thick layer of connective tissue
What is the mucous membranes?
Lines body cavities that are open to the exterior; bathed by secretions or urine
What are the two layers of the mucous membrane
Epithelial sheet and lamina propria (loose connective tissue)
What is a serous membrane?
Line body cavities that are closed to the exterior
What are the layers of the serous membranes?
Thin areolar connective tissue and simple squamous epithelium
What are the the two types of repair for tissues
Regeneration and Fibrosis
Regeneration
Same kind of tissue replaces destroyed tissues, so original function is restored
Fibrosis
Connective tissue replaces destroyed tissue, and original function lost
What are the three step of repair
Inflammation
Organization
Regeneration
Tissues that regenerate extremely well
Epithelial tissues, bone, areolar connective tissue, dense irregular connective tissue, blood-forming tissue
Tissues that regenerate moderate amount
Smooth muscle and dense regular connective tissue
Tissues that regenerate poorly
Cardiac muscle and nervous tissue
Primary Germ Layers
Ectoderm mesoderm endorm
What does Blood Tissue look like?
Red and White blood cells un fluid matrix
What is the function of blood tissue
Transports gases, nutrients, wastes, etc
Where is Blood tissue located
Within blood vessels.
Is the Bone innervated
Yes is is innervated, containing neerves
What does the bone store
Calcium and fat
Is the bone highly vascular
Yes, it is highly vascular
What are the individual structural units of bones
Osteons
What does the bone tissue look like
Looks like the inside of a tree, hard calcified matrix, many collagen fibers, osteocytes in lacunae
What is the functions of bone tissue
Supports and protects, stores calcium, minerals and fat, provides levers for locomotion.
Where is the site of blood cell formation
Bone tissue
Where is the bone tissue located
In the bones
What does the areolar tissue look like
Gel-like matrix, collagen, elastic, and reticular fibers, fibroblasts, macrophages
What is this a picture of
Areolar connective tissue
What is the function of areolar tissue
Cushions and protects organs, holds and moves tissue fluids
Where is areolar connective tissue found
Distributed under epithelial layers
What is this a picture of
Adipose tissue
What is this a picture of
Reticular tissue