SCI 140 MT2

Are all mutations bad?

No some are helpful and useful.

What are 2 examples of how mutation is useful?

1. Resistance to malaria

2. Lactose Tolerance

How is mutation neutral?

Change in DNA that doesn’t affect a protein.

What makes mutation harmful?

Leads to disease or malfunction like cancer

Who is Charles Darwin?

Figured out natural selection more importantly Galapagos finches.

1. 4 causes of mutation?

1. Error in replication

2. Inherit it

3. Environmental

4. Accumulation over time

What is inherited mutation?

Passed from parent to child

What is acquired mutation?

Develop over time

What is x-link mutation?

Common in male such as hemophilia.

What is y-linked mutation?

Rare, only affects male

Can females be carriers of x-linked disorder?

Yes w/o having the conditions themselves

What is Sickle cell anemia?

point mutation in hemoglobin gene, disrupted oxygen transport

What is cystic fibrosis?

Recessive mutation in a gene disrupts salt transport in the body.

What is tay-sachs?

Porgressive damage to nervous system starting in infnacy

What is a hallmark of cancer?

Uncontrolled cell growth

When can mutation test be used?

Prenatal or later in life