a large bundle of nerve fibers that connects corresponding parts of one side of the brain with those of the other
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split-brain operation
brain surgery that is occasionally performed to treat a form of epilepsy; the surgeon cuts the corpus callosum, which connects the two hemispheres of the brain
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cerebral hemispheres
the two symmetrical halves of the brain; they constitute the major part of the brain
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generalization
type of scientific explanation; a general conclusion based on many observations of similar phenomena
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reduction
type of scientific explanation; a phenomenon is described in terms of the more elementary processes that underlie it
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reflex
an automatic, stereotyped movement produced as the direct result of a stimulus
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model
a mathematical or physical analogy for a physiological process
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doctrine of specific nerve energies
Muller’s conclusion that because all nerve fibers carry the same type of message, sensory information must be specified by the particular nerve fibers that are active
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experimental ablation
the research method in which the function of a part of the brain is inferred by observing the behaviors an animal can no longer perform after that part is damaged
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functionalism
the principle that the best way to understand a biological phenomenon is to try to understand its useful functions for the organism
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natural selection
the process by which inherited traits that confer a selective advantage become more prevalent in the population
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evolution
a gradual change in the structure and physiology of plant and anima species - generally producing more complex organisms - as a result of natural selection
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mutation
a change in the genetic information contained in the chromosomes of sperms or eggs, which can be passed on to an organism’s offspring; provides genetic variability
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selective advantage
a characteristic of an organism that permits it to produce more than the average number of offspring of its species
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behavioral neuroscientist
a scientist who studies the physiology of behavior, primarily by performing physiological and behavioral experiments with laboratory animals
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neuraxis
an imaginary line drawn through the center of the length of the central nervous system, from the bottom of the spinal cord to the front of the forebrain
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anterior
located near or toward the head
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posterior
located near or toward the tail
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rostral
“toward the beak”; in a direction along the neuraxis toward the front of the face
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caudal
“toward the tail”; in a direction along the neuraxis away from the front of the face
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dorsal
“toward the back”; perpendicular to the neuraxis toward the top of the head or the back
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ventral
“toward the belly”; perpendicular to the neuraxis toward the bottom of the skull or the front surface of the body
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lateral
toward the side of the body, away from the middle
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medial
toward the middle of the body, away from the side
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ipsilateral
located on the same side of the body
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contralateral
located on the opposite side of the body
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central nervous system
brain
spinal cord
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peripheral nervous system
nerves
peripheral ganglia
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cross section
a slice taken at right angles to the neuraxis
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frontal section
a slice through the brain parallel to the forehead
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horizontal section
a slice through the brain parallel to the ground
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sagittal section
a slice through the brain parallel to the neuraxis and perpendicular to the ground
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midsagittal plane
the plane through the neuraxis perpendicular to the ground; divides the brain into two symmetrical halves
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meninges
the three layers of tissue that encase the CNS; the dura mater, arachnoid membrane, and pia mater
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dura mater
the outermost of the meninges; tough and flexible
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arachnoid membrane
the middle layer of the meninges, located between the outer dura mater and inner pia mater
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pia mater
the layer of the meninges that clings to the surface of the brain; thin and delicate
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subarachnoid space
the fluid-filled space that cushions the brain; located between the arachnoid membrane and the pia mater
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cerebrospinal fluid (CSF)
a clear fluid, similar to blood plasma, that fills the ventricular system of the brain and the subarachnoid space surrounding the brain and spinal cord
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ventricle
one of the hollow spaces within the brain, filled with cerebrospinal fluid
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lateral ventricle
one of the two ventricles located in the center of the telencephalon
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third ventricle
the ventricle located in the center of the diencephalon
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cerebral aqueduct
a narrow tube interconnecting the third and fourth ventricles of the brain, located in the center of the mesencephalon
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fourth ventricle
the ventricle located between the cerebellum and the dorsal pons, in the center of the metencephalon
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choroid plexus
the highly vascular tissue that protrudes into the ventricles and produces cerebrospinal fluid
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neural tube
a hollow tube, closed at the rostral end, that forms ectodermal tissue early in embryonic development; serves as the origin of the CNS
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cerebral cortex
the outermost layer of gray matter of the cerebral hemispheres
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progenitor cells
cells of the ventricular zone that divide and give rise to cells of the CNS
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ventricular zone (VZ)
a layer of cells that line the inside of the neural tube; contains progenitor cells that divide and give rise to cells of the CNS
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symmetrical division
division of a progenitor cell that gives rise to two identical progenitor cells; increases the size of the ventricular zone and hence the brain that develops from it
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asymmetrical division
division of a progenitor cell that gives rise to another progenitor cell and a neuron, which migrates away from the VZ toward its final resting place in the brain
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radial glia
special glia with fibers that grow radially outward from the VZ to the surface of the cortex; provide guidance for neurons migrating outward during brain development
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neurogenesis
the production of new neurons within the brain
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forebrain
the most rostral of the three major divisions of the brain; includes the telencephalon and diencephalon
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cerebral hemisphere
one of the two major portions of the forebrain, covered by the cerebral cortex
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subcortical region
the region located within the brain, beneath the cortical surface
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sulcus/sulci
a groove, smaller than a fissure, in the surface of the cerebral hemisphere
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fissure
a major groove in the surface of the brain
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gyrus/gyri
a convolution of the cortex of the cerebral hemispheres, separated by sulci or fissures
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primary visual cortex
the region of the posterior occipital lobe whose primary input is from the visual system
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calcarine fissure
a fissure located in the occipital lobe on the medial surface of the brain; most of the primary visual cortex is located along its upper and lower banks
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primary auditory cortex
the region of the superior temporal lobe whose primary input is from the auditory system
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lateral fissure
the fissure that separates the temporal lobe from the overlying frontal and parietal lobes
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primary somatosensory cortex
the region of the anterior parietal lobe whose primary input is from the somatosensory system
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central sulcus
the sulcus that separates the frontal lobe from the parietal lobe
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primary motor cortex
the region of the posterior frontal lobe that contains neurons that control movements of skeletal muscles
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frontal lobe
the anterior portion of the cerebral cortex, rostral to the parietal lobe and dorsal to the temporal lobe
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parietal lobe
the region of the cerebral cortex caudal to the frontal lobe and dorsal to the temporal lobe
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temporal lobe
the region of the cerebral cortex rostral to the occipital lobe and ventral to the parietal and frontal lobes
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occipital lobe
the region of the cerebral cortex caudal to the parietal and temporal lobes
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sensory association cortex
those regions of the cerebral cortex that receive information from the regions of primary sensory cortex
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motor association cortex
the region of the frontal lobe rostral to the primary motor cortex; aka the premotor cortex
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prefrontal cortex
the region of the frontal lobe rostral to the motor association cortex
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corpus callosum
a large bundle of axons that interconnects corresponding regions of the association cortex on each side of the brain
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neocortex
the phylogenetically newest cortex, including the primary sensory cortex, primary motor cortex, and association cortex
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limbic cortex
phylogenetically old cortex, located at the medial edge of the cerebral hemispheres; part of the limbic system
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cingulate gyrus
a strip of limbic cortex lying along the lateral walls of the groove separating the cerebral hemispheres, just above the corpus callosum
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limbic system
a group of brain regions including the anterior thalamic nuclei, amygdala, hippocampus, limbic cortex, and parts of the hypothalamus, as well as their interconnecting fibers
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hippocampus
a forebrain structure of the medial temporal lobe, constituting an important part of the limbic system; involved in learning and memory
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amygdala
a structure in the interior of the rostral temporal lobe, containing a set of nuclei; part of the limbic system
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fornix
a fiber bundle that connects the hippocampus with other parts of the brain, including the mammillary bodies of the hypothalamus; part of the limbic system
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mammillary bodies
a protrusion of the bottom of the brain at the posterior end of the hypothalamus, containing some hypothalamic nuclei; part of the limbic system
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basil ganglia
a group of subcortical nuclei in the telencephalon, the caudate nucleus, the globus pallidus, and the putamen; important parts of the motor system
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nucleus
an identifiable group of neural cell bodies in the CNS
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diencephalon
a region of the forebrain surrounding the third ventricle; includes the thalamus and hypothalamus
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thalamus
the largest portion of the diencephalon, located above the hypothalamus; contains nuclei that project information to specific regions of the cerebral cortex and receive info from it
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projection fiber
an axon of a neuron in one region of the brain whose terminals form synapses with neurons in another region
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lateral geniculate nucleus
a group of cell bodies within the lateral geniculate body of the thalamus that receives fibers from the retina and projects fibers to the primary visual cortex
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medial geniculate nucleus
a group of cell bodies within the medial geniculate body of the thalamus; receives fibers from the auditory system and projects fibers to the primary auditory cortex
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ventrolateral nucleus
a nucleus of the thalamus that receives inputs from the cerebellum and sends axons to the primary motor cortex
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hypothalamus
the group of nuclei of the diencephalon situated beneath the thalamus; involved in regulation of the automatic nervous system, control of the anterior and posterior pituitary glands, and integration of species-typical behaviors
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optic chiasm
an X-shaped connection between the optic nerves, located below the base of the brain, just anterior to the pituitary gland
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anterior pituitary gland
the anterior part of the pituitary gland; an endocrine gland whose secretions are controlled by the hypothalamic hormones
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neurosecretory cell
a neuron that secretes a hormone or hormonelike substance
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posterior pituitary gland
the posterior part of the pituitary gland; an endocrine gland that contains hormone-secreting terminal buttons of axons whose cell bodies lie within the hypothalamus
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midbrain
the mesencephalon; the central of the three major divisions of the brain
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mesencephalon
the midbrain; a region of the brain that surrounds the cerebral aqueduct; includes the tectum and tegmentum
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tectum
the dorsal part of the midbrain; includes the superior and inferior colliculi
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superior colliculi
protrusions on top of the midbrain; part of the visual system
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inferior colliculi
protrusions on top of the midbrain; part of the auditory system