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Lymph
A clear watery liquid formed from interstitial fluid found between cells.
Interstitial fluid
Fluid found between cells; 90% returns to capillaries and 10% enters lymphatic vessels.
Lymphatic vessels
Vessels that carry lymph to lymph nodes.
Lymph capillaries
Small lymph vessels that have 'dead ends' and are lined with overlapping epithelial cells.
Lymph nodes
Capsules of connective tissue that filter lymph and produce immune cells.
Afferent lymphatic vessels
Vessels that carry lymph to the lymph nodes and slow down the flow.
Efferent lymphatic vessels
Vessels that carry lymph away from lymph nodes and also slow down the flow.
Thymus
An organ involved in the endocrine and lymphatic systems, where T-lymphocytes are formed in bone marrow and protect the body from infection DO NOT FILTER
Germinal centers
Areas within lymph nodes where immune cells rapidly multiply to fight off invaders.
Spleen
An organ that protects the body from infection and filters blood and removes worn-out red blood cells; contains white and red pulp. DO NOT FILTER
Peyer's Patches
Lymphoid tissues in the intestine that filter bacteria from food.
MALT
Mucosa-associated lymphoid tissues that trap foreign invaders.
Innate immunity
The body's first line of defense against pathogens, including physical barriers and immune cells.
Phagocytes
Cells like neutrophils and macrophages that 'eat' foreign invaders.
Memory B cells
Long-lived B cells that respond quickly upon re-encountering the same antigen.
Plasma B cells
B cells that produce antibodies to neutralize and immobilize pathogens.
Active immunity
Immunity developed by the generation of one's own antibodies.
Passive immunity
Immunity borrowed from another individual; does not involve the production of antibodies.
Cytokines
Chemical signals that help cells communicate during an immune response.
Antigens
Substances that trigger an immune response.
Humoral immunity
The aspect of immunity that involves B cells and the production of antibodies.
Cell-mediated immunity
The aspect of immunity that involves T cells responding to infected cells.
APC (Antigen-Presenting Cell)
Cells that engulf antigens and present them to activate other immune cells.
MHC-2
Major Histocompatibility Complex class 2, receptors that present antigens on APCs.
Secondary immune response
The immune response upon re-exposure to an antigen; faster and stronger due to memory cells.
Natural active immunity
Immunity gained from contracting an illness, such as the flu.
Artificial active immunity
Immunity gained through vaccination.
Natural passive immunity
Immunity passed from mother to baby through breast milk.
Artificial passive immunity
Immunity gained through the administration of antibodies from another individual.
Regulatory T cells
Cells that secrete signals to slow down the immune response after a threat is eliminated.
Neutrophils
A type of phagocyte that responds quickly to infection.
Macrophages
Large phagocytic cells that engulf and digest pathogens.
Basophils
White blood cells that release chemicals to promote inflammation.
Complement proteins
Proteins that aid in lysing bacteria and enhancing immune responses.
Interferons
Proteins secreted by virally infected cells that warn nearby cells of infection.
Skin oil and sweat
External barriers that decrease bacterial growth.
Mucous membranes
Barriers that trap and sweep pathogens away from the body.
T-lymphocytes
A type of white blood cell that is important for cell-mediated immunity.
Thymosin
Hormone released by the thymus to aid in the maturation of T-lymphocytes.
Edema
Swelling due to inflammation that helps macrophages reach the site of infection.
Pyrogenic response
Fever response that occurs during an immune reaction.
Tonils
A protective ring of lymphoid tissues that trap foreign invaders.
Lymphoid organs
Organs such as the spleen and thymus that are involved in immunity.
B cells
Lymphocytes that produce antibodies and can act as APCs.
Helper T cells
T cells that activate other immune cells when presented with antigens.
Cytotoxic T cells
T cells that kill infected or abnormal cells.
Memory T cells
Long-lived cells that facilitate a swift immune response upon re-exposure to an antigen.
Immune system memory
The ability of the immune system to remember past infections for a faster response.
Cloned plasma B cells
B cells that are rapidly produced to fight an antigen after initial stimulation.
Agglutination
The clumping of pathogens caused by antibodies, making them easier for phagocytes to eliminate.
Skeletal muscle pressure
Helps push lymph through lymphatic vessels.
Tonsils
Lymphoid tissues that help to trap foreign invaders entering via the throat.
Artificial blood serum
Containing antibodies from another individual used for passive immunity.
Vaccination
A method to provoke an immune response by introducing a harmless form of an antigen.
Thymic education
Recognize foreign invaders