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a fertilized ovum + sperm =
zygote
a process in the ovum phase where rapid cell division occurs
cleavage
T/F the ovum phase has no morphogenesis or differentiation
true
T/F cleavage has no protein synthesis
true
cleavage is an ______ in cell number, and a ______ in cell size
increase, decrease
what prevents cells going through cleavage from growing in size?
zona pellucida
a process where cells begin to differentiate. developed are a blastocoel, trophoblast layer and inner cell mass
blastulation
stage in cleavage where the zygote has reached a 32 cell limit
morula
outer cell layer of a blastula which allows for implantation and becomes the fetal portion of the placenta
trophoblast
formed during blastulation and will become the embryo
inner cell mass
the process defined by lengthening of the fetal tissues from oval → tubule → filamentous shape
elongation
what must occur before elongation
hatching
the precursor to elongation where the zona pellucida degenerates
hatching
increasing placental surface area for nutrient exchange is the purpose of this process
elongation
what species do not elongate, but continue with spherical growth?
horses and humans
T/F the conceptus is known as an embryo or fetus during implantation
false
a process occurring 1-5 weeks after fertilization dependent on the species
implantation
a process where the conceptus embeds itself into the endometrium of the uterus
implantation
what key hormone allows implantation?
progesterone
this hormone is known for its ability to maintain pregnancy, or as the hormone of pregnancy
progesterone
this hormone works by increasing the vascularity of the uterus and increasing glycogen secretions, while inhibiting muscular contractions
progesterone
this molecule is stored glucose that is used by the fetus for nutrients and energy
glycogen
in the endometrium of humans and mice, this prepares the uterus and conceptus and without it implantation can not occur. In cattle however, it is believed to be involved in cell differentiation, not implantation. Endometrial glands produce and secrete this.
Leukemia Inhibitory Factor
during this process, the inner cell mass pushes to one side of the blastocyst to form an embryonic disc
implantation
term used to describe why dam allows implantation to occur
maternal recognition of pregnancy
a receptor on the maternal cytotoxic T cells
Fas
this binds to Fas and causes apoptosis of cytotoxic T cells
Fas Ligand
this is produced by trophoblasts to destroy tryptophan
Indoleamine 2,3 dioxygenase
this amino acid activates maternal cytotoxic T cells
tryptophan
general idea behind dam allowing implantation
limiting maternal immunity
this occurs in ruminants to effect their hormone cycle. acts on the uterine epithelium to decrease estrogen and oxytocin and in result, decrease PGF2a.
Interferon Tau
in ruminants, these are endogenous retroviruses that form the feto-maternal interface
syncytial plaques
in non-ruminants, these are endogenous retroviruses that form the feto-maternal interface
syncytiotrophoblast
this is responsible for nutrient exchange, hormone secretion and also serves an immune modulator to decrease dam’s immune system
feto-maternal interface
solid ball of cells formed as the zygote undergoes cleavage
morula
hollow ball of cells with a fluid-filled cavity
early blastocyst
pre-embryo, with the embryonic disk, two layers of cells that become the embryo proper
late blastocyst
embryo with three primary germ layers (ectoderm, endoderm, mesoderm)
gastrula
this phase can be described as the formation of an embryo in hyperplastic growth with multipotent cells which will be different cell lineages
embryonic phase
these are derived from multipotent cells and will eventually form different tissues and are driven by gene expression
cell lineages
steps of this process are: implantation, gastrulation, neurulation, embryonic folding and organogenesis
embryonic phase
the formation and development of the gut is known as…
gastrulation
epiblast cells replicate to form the…
primitive streak
epiblast cells migrate toward the hypoblast to form ______.
germ layers
name the germ layers
ectoderm, mesoderm, endoderm
a depression formed in the bilaminar disk is called the
primitive groove
the inner cell mass morphs into ______ and _____ cells
hypoblast, epiblast
the outer germ layer
ectoderm
the middle germ layer
mesoderm
the inner germ layer
endoderm
this layer will develop to form the: integument, sensory organs, oral cavity, nervous system, mammary glands, and sweat glands
ectoderm