Listeria

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5 Terms

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Pneumonic

Listeria ACTs like a mimic

2
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pverview disease

20-30% death rate, causes listeriosis, diarrhea, GI infection, memningiencephilitis, abortions

3
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How does literia enter cell

Goblet cell, InIa - binds ecad, internalised into vacuole, enzymeatic escape from vacuole

4
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how does it do actin based motility

ActA  (an NFB) activates ARB (mimic) which activates actin pol. 

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how does listeria spread into next cell

ABM, InIc disruots TUBA - decreases CT