Neuroanatomy Exam 1

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Philosophy

104 Terms

1
Dynamic systems theory
any system including the human nervous system can be studied at various levels of analysis
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2
Microscopic
molecules and cells in the nervous system
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3
Mesoscopic
groups of cells linked together in various systems
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Macroscopic
the whole human interacting in their environment
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5
Distributed control
at any one time the nervous system coordinates many different activities
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6
Adaptation
the human nervous system is able to change which can lead to changes in behavior and can be shaped by the environment
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7
Neuro-occupation
reciprocal relationship between the nervous system and occupation
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8
Localization of function
particular structure in the nervous system can be loosely tied to particular functions
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9
Topographical organization
the brain can loosely be compared to a map
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10
Brodmann’s areas
classification system which uses numbers to label individual areas of the cortex that are cellularly similar
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11
Hemispheric specialization
each hemisphere of the brain is connected to some specific functions
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12
Phylogenetic layers
most newer parts of our brain are located at the top of our head and more primitive parts are located deeper and lower
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Crossed representation
for most sensory and motor functions, the left side of the brain functionally corresponds to the right side of the body and vice versa
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14
Cell
Cell body
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15
Nerve fibers
Dendrites and axons
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16
White matter
white tissue of the CNS rich with myelinated axons
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17
Gray matter
gray tissue of the CNS rich with neuronal cell bodies (nuclei)
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18
Glial cells, neuroglia, glia
non-neural cells
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19
Sulcus (sulci)
crevices of the brain (2/3s) of the brain is found in the sulci)
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20
Gyrus (gyri)
ridges of the brain
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21
Fissure
a deep sulcus
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22
Cortex
outer layer of an organ or body structure
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23
Group(s) of functionally or structurally related cell bodies (CNS)
nucleus (nuclei)
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24
Groups(s) of functionally or structurally related cell bodies (PNS)
ganglion (ganglia)
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25
Group(s) of parallel axons (CNS)
tract, fasciculus, lemniscus, peduncle
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Group(s) of parallel axons (PNS)
nerve, ramus, root
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Group(s) of several parallel tracts or fasciculi
funiculus, column
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Group of axons connecting one side of the CNS with the other
commisure
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Group(s) of functionally related cells that from a layer
layer, lamina, stratum
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30
CNS
brain and spinal cord which are enclosed by bone
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31
PNS
extension of the CNS that includes 12 pairs of cranial nerves and 31 pairs of spinal nerves which aren’t encased by bone or protected by the blood-brain barrier
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Autonomic nervous system (ANS)
innervates smooth muscle and glands; regulates homeostasis
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Somatic nervous system (SNS)
innervates mainly musculoskeletal tissue and skin
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34
What is in the diencephalon?
cerebellum and brainstem (midbrain, pons, and medulla)
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What cells form the PNS?
Neural crest cells
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Sulcus limitans
longitudinal groove in wall of the neural tube in the 4th week
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37
What is dorsal to the sulcus limitans?
the alar plate
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38
What function does the alar plate have?
sensory functions
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39
What is ventral to the sulcus limitans?
the basal plate
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40
What function does the basal plate have?
motor functions
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41
What are the 3 primary vesicles?
prosencephalon, mesencephalon, and rhombencephalon
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42
What are the 5 secondary vesicles?
telencephalon, diencephalon, mesencephalon, metencephalon, myelencephalon
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43
Cervical flexure
between future brainstem and spinal cord; straightens later in development
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Cephalic flexure
between future midbrain and diencephalon; persists in adulthood and is the reason for “the bend” in the neural axis
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Pontine flexure
between future pons and medulla; does not persist but affects caudal brainstem
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Teratogens
drugs or other agents that cause atypical development
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Craniorachischisis
complete failure of neural tube to close; incompatible with life
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Spina bifida occulta
atypical formatin of vertebral column only
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Meningocele
herniation of meninges only
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50
Myelomeningocele
herniation of spinal cord and meninges
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Anencephaly
failure of rostral end of tube to close resulting in absent cerebral hemispheres; incompatible with life
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Holoprosencephaly
partial or complete failure of prosencephalon to separate into diencephalon and telencephalon; usually fatal
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Nature
general layout of the nervous system
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Nurture
various connections are adjusted to meet demands of environment; also known as neuroplasticity
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Critical periods
early development
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Ongoing adjustments
learning and memory; constraint-induced movement therapy; etc
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Neuroplasticity
the ability of the brain to change its own structure and function through activity and thought
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Neurogenesis
creating new neurons
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Neural stem cells
cells that can produce new CNS neurons or glial cells
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Re-wiring
creating new neuronal pathways
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Unmasking
uncovering existing, but rarely used neuronal pathways
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Cortical re-organization
reassigning cortical “real estate”
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Changes in synaptic efficiency
basis if learning and memory
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Potentiation
an increase in synaptic efficiencyD
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Depression
a decrease in synaptic efficiency
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Short-term potentiation or depression
lasts a few minutes
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Long-term potentiation or depression
produces lasting changes (hours to years); basis of learning and memory and what we hope to affect in neurorehab
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Neuronal competetition
neurons compete for neurotropic factors during development
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What are the 2 types of long-term memory?
declarative memory and nondeclarative memory
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Declarative (explicit) memory
memory of facts, events, concepts, places
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Nondeclarative (implicit) memory
also know as procedural memory; how-to memory
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What are the 3 stages of declarative memory?
immediate memory, working memory, and long term memory
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Retrograde amnesia
loss of memories from a period prior to the brain injury
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Anterograde amnesia
deficit in forming new memories
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What are the 3 general types of nondeclarative memory?
skills and habits, emotional associations, and conditioned reflexes
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What are the 3 stages involved in motor learning?
cognitive, associative, and autonomous
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Cognitive stage of motor learning
verbally guide motor task; requires much attention
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Associative stage of motor learning
movement is refined and made more efficient
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Autonomous stage of motor learning
movements are practically automatic; requires very little conscious attention
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80
What areas of the brain are most affected in a TBI?
anteromedial temporal lobes and basal orbitofrontal cortex
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81
How is memory affected with Karsakoff’s psychosis?
affects mammillary bodies and is characterized by anterograde amnesia and may lead to confabulation
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Confabulation
filling in memory gaps by fabrication
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What memory structures does Alzheimer’s affect?
bilateral hippocampus, temporal, and basal forebrain structures
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Psychogenic amnesia
memory loss of an emotional event or autobiographical information due to dissociation and repression
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85
What are the meninges comprised of?
collagen fibrils and fibroblasts
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86
What are the 3 meninges?
dura mater, arachnoid mater, and pia mater
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87
What are the 2 layers of the dura mater?
periosteal layer and meningeal layer
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88
Falx cerebri
vertically oriented separating cerebral hemispheres
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Subarachnoid space
between arachnoid and pial membranes and filled with csf
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Arachnoid trabeculae
connective tissue arising from arachnoid and connect the arachnoid to the pia
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Subarachnoid cisterns
enlargements in the subarachnoid space
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What is the largest cistern?
cisterna magna
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Arachnoid granulations (large) or villi (small)
small tufts of arachnoidal tissue project into dural sinuses
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What are the 5 types of intracranial hemorrhage?
epidural hematoma, subdural hematoma, subarachnoid hemorrhage, intracerebral hemorrhage, and intraventricular hemorrhage
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Spinal dura
single-layered (unlike dura mater)
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Spinal epidural space
is an actual space which is used clinically for epidural anesthesia
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Lumbar cistern
widest area of subarachnoid space in the spinal cord
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98
Meningitis
inflammation of the meninges from pressure in the lungs
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99
Meningocele
protrusion of the meninges outside of the vertebral canal
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100
What are the 5 basic components of the lateral ventricles?
anterior horn, body, posterior horn, inferior horn, and atrium
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