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neurons (brain cells)
are the basic components of the entire nervous system
synapses
tiny gaps between neurons
dendrites (tress)
receiving portion of neuron and many branches to increase neuron’s surface area
Soma (Cell Body)
makes proteins and building blocks of neurotransmitters (chemical messengers) - is vital to cell function
Axons
sending portion of neuron; long thin fibre
axon terminal:
end of the axon which contains synaptic vesicles with neurotransmitters
myelin sheath:
white, fatty substance that insulates signal
synapse:
gap between neurons - information is exchanged here
what are the 3 types of neurons
sensory
motor
interneurons
what the sensory neurons (receptors) do?
receive input from the sensory organs (eyes, ears, nose, mouth, skin) and send it to the brain
what the motor neurons (effectors) do?
send output from the brain to muscles and organs, enabling the body to move
what are the interneurons (processors)?
are thousands of times more numerous than sensory and motor neurons, and relay information between neurons in the brain
how do neurons communicate?
neurons communicate by chemical and electrical activity, messages within or inside neurons are electrical
what is the 3 different types of ions passing in and out of them different rates
chloride (-)
potassium (+)
sodium (+)
neurons at rest are…
are polarized
what being polarized?
electrical charge inside is negative (-), but electrical charge outside is positve (+)
what incoming messages from other neurons can generate
neural impulse
action potential
sodium ions rush in and out along the axon, propagating the electrical signal
how is the electrical state on the action potential?
it is depolarized
how is the all-or-none law
once impulse = generated
what happens with neurons after firing?
cannot fire again for a brief time
how we called the period after firing
absolute refractory period
how is the electrical state
hyperpolarized
what hyperpolarized means
electrical charge inside is even more negative than at rest
why the electrical charge inside is even more negative than at rest
chloride negative ions flow in and positive neurons flow out and neuron must get back to resting potential
how neurons communicate
by chemical and electrical activity
what is chemical
messages between or outside neurons
what are the neurotransmitters
the neurotransmitters
after an action potential, the neurotransmitters…
are released from the axon terminal into the synapse and received by dendrites of the next neuron
who said that single neurons don’t influence behavior
Donald Hebb
Donald Hebb explained…
that neurons constantly communicate with each other,
the basis of learning they fire together so forms links together “fire together, wire together”
what is the long term potentiation
persistent strengthening of synapses based on recent patterns of activity
so… the hebbian learning is…
when two joining cells fire simultaneously, the connection between them strengthens
what are the two types of messages from neurotransmitters?
excitatory
inhibitory
the excitatory neurotransmitters…
increases the chance that the postsynaptic neuron will activate and generate an action potential
the inhibitory neurotransmitters…
decreases the chance that the postsynaptic neuron will activate and generate an action potential
what are the two ways to call the chemicals mimic neurotransmitters
agonists
antagonists
acetylcholine
found in all motor neurons; it stimulates the muscles to contract, but also involved in learning and memory
what are the monoamines?
dopamine
serotonin
noretonin
dopamine
linked to feelings of pleasure or desire, but also involved in body movement, memory, attention, sleep
serotonin
linked to mood/emotion, anxiety, behavior, learning, sleep, sexuality, appetite
norepinephrine (noradrenaline)
linked to body’s response to fear or threat, but also involved in sleep, learning, memory
Gaba (gamma-aminobutyric acid)
has an inhibitory effect on the nervous system - it slows down transmission of nerve impulses, relaxes muscles
glutamate
has an excitatory effect on the nervous system - important for learning memory, and sensory processes
endorphins
chemically similar to morphine (and other opiates), and are released in response to stress, trauma, and pain
glia
support cells (glue) of the nervous system 10 x more numerous than neurons
oligodendrocytes
form myelin sheath covering of axons (in the brain and spine) or Schwann cells (in the rest of the body)
astrocytes
provide nutrients to neurons, help communication between neurons, and provide connections between neurons and blood vessels
microglia
remove debris, waste, and damaged cells from nervous system
nervous system
peripheral
central (brain and spinal cord)
peripheral
autonomic (controls self-regulated action of internal organs and glands)
somatic (controls voluntary movements of skeletal muscles)
autonomic
sympathetic (arousing)
parasympathetic (calming)
somatic nervous system:
control voluntary behavior
contains sensory and motor nerves
sends sensory info to CNS, and carries info from CNS along motor nerves for voluntary movement
autonomic nervous system:
controls involuntary functions (heartbeat, breathing, digestion)
activates fight-or-flight response
sympathetic nervous system:
body’s emergency system (activates body in response to threat or emergencies)
parasympathetic nervous system:
body’s conservation system (conserves and maintains body’s resources, calms you down after an emergency)
how the brain is protected
by the skull and cranium
how the spinal cord is protected
by the vertebral column
what are the 3 membranes that evelop the brain and spinal cord
dura mater
arachnoid mater
pia mater
what is cerebrospinal fluid (CSF)
located between the arachnoid mater and pia mater
what is the primary function of cerebrospinal fluid
protect the CNS
what are the 3 main components
forebrain
midbrain
hindbrain
cerebrum
largest part of the brain
controls voluntary actions, senses, and cognitive functions
how the surface is called
cerebral cortex
cerebral cortex
is made up of gray matter (neuron cell bodies) and is folded up so that it can fit inside the skull
hills or bumps
gyri (singular = gyrus)
valleys or grooves
sulci (singular = sulcus)
the right hemisphere of the cerebrum
controls voluntary limb movements on left side of the body - contralateral control
left hemisphere of cerebrum
controls voluntary limb movements on right side of the body - contralateral control
what links the two cerebral hemispheres
corpus callosum
nerve fibres
white matter
myelin
white, fatty substance that forms an electrically insulating
what are the 4 cerebral lobes
frontal
pariental
occiptal
temporal
frontal lobe
primary motor cortex: voluntary body movements
broca’s area: language production
executive functions: thinking, planning, decisions
contains mirror neurons
pariental lobe
primary somatosensory cortex: sensations of pressure, pain, temperature
space and object orientation
occipital lobe
vision
temporal lobe
hearing, complex facial tasks
wernicke’s area: language understanding
frontal lobe damage
phineas gage
phineas gage
difficulty reasoning, making decisions
inability to control emotions
goal-directed behavior impairments
damage on broca’s area
expressive aphasia - difficulty producing speech
occipital lobe damage
blindness/visual hallucinations
temporal lobe damage
wernicke’s area
receptive aphasia (difficulty understanding language)
basal ganglia
control of voluntary movement (with the help of the motor cortex), routine behaviors or habits such as teeth grinding, eye movements, cognition, and emotion
basal forebrain
activates cerebral cortex, attention
thalamus
sensory gateway to the cerebral cortex functions as a relay station for all sensory impulses to the cerebral cortex EXCEPT for smell
Limbic system
emotional center
networked with the autonomic nervous system to influence blood pressure, heart, and endocrine system
conveys information about our internal state
the limbic system consists:
hypothalamus
amygdala
cingulate cortex
hippocampus
hypothalamus:
maintains the body’s internal states (homeostasis) by overseeing the endocrine and autonomic nervous systems
amygdala:
plays a key role in the processing of emotions, especially fear and pleasure, and also plays a role in memory
cingulate cortex:
involved in emotional expression
knowledge of socially appropriate behavior
regulates autonomic nervous system
hippocampus
spatial memory, fear conditioning
midbrain
integrates sensory processes, such as vision and hearing
contains an important network of dopamine-producing neurons
reticular formation
modulates muscle reflexes, breathing, pain perception, sleep and arousal
hindbrain
contains two important structures
brainstem
cerebellum
brainstem
oldest part of the brain, beginning where the spinal cord swells and enters the skull
responsible for automatic survival functions
what are the 3 structures make up the brainstem
medulla oblongata
pons
midbrain
medulla oblongata
crucial for life, it controls breathing, swallowing, blood pressure, and heart rate
pons (latin for bridge)
links cerebrum to cerebellum and relays signals between them - also plays a key role in sleep and dreaming
midbrain
controls rudimentary vision and hearing
cerebellum (little thing under the cerebral)
means little brain in latin
responsible for balance and coordination of muscles
important for voluntary tasks (walking, reaching, writing)