one or more cells comprise all organisms, the cell is the basic unit of life, new cells arise from existing cells
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all cells have:
plasma membrane, cytoplasm, DNA, ribosomes
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prokaryote
a simple, mostly single-celled organism that lacks a nucleus, or any other membrane bound organelle. Most have a peptidoglycan cell walls and polysaccharide capsule
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nucleiod
central part of a prokaryotic cell where the chromosome is located
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prokaryotic cells are
0.1-5.0 micro meters in diameter while eukaryotic cells are 10 to 100 micrometers in diameter
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As a cell gets larger, it becomes:
less efficient
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eukaryotic cells
cell that has membrane-bound nucleus and several other membrane-bound compartments
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Eukaryotic cells have:
a nucleus and membrane-bound organelles (mitochondria, vacuole, and chloroplast, endoplasmic reticulum, other chromosomes)
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plasma membrane
phospholipid bilayer with embedded or attaches proteins, separates the cell's internal content from its surviving environment, controls passage of molecules
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Phospholipid
a lipid molecule with two fatty acid chains and a phosphate-containing group
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What limits prokaryote cell size?
Diffusion over long distances, DNA, ratio of SA:Volume
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Microvilli
Fingerlike extensions of plasma membrane of apical epithelial cells, increase surface area, aid in absorbtion, exist on every moist epithelia, but most dense in small intestine and kidney
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cytoplasm
entire region between the plasma membrane and the nuclear envelope, consisting of organelles suspended in gel-like cytosol, cytoskeleton, chemicals
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nucleus
organelle composed of a double membrane that houses the cell's DNA and directs the ribosome and protein synthesis
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nuclear envelope
the double-membrane structure that constitutes the outermost portion of the nucleus, is punctuated with pores
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nucleoplasm
semi-solid fluid inside the nucleus that contains the chromatin and nucleolus
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chromosomes
structure within the nucleus that comprises chromatin that contains DNA, linear in eukaryotes, singular and circular in prokaryotes
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chromatin
protein-DNA complex that serves as the building material of chromosomes. Strands so that it can be read in order to send messages to proteins
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nucleolus
region, darkly staining body w/in the nucleus that is responsible for assembling ribosome subunits
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ribosomes
cellular structure that carries out protein synthesis. May float freely in cytoplasm or attach to cytoplasm or endoplasmic reticulum. Consists of two subunits (small and large). Receives orders from nucleus.
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___ are particularly abundant in cells that
synthesize lost of protein, ex= pancreas
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mitochondria
responsible for carrying out cellular respiration, resulting in producing ATP, high concentration in muscle cells
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cellular respiration
process of making ATP using chemical energy in glucose and other nutrients, uses O and produces CO2 as waste
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mitochondria
each membrane is a phospholipid bilayer embedded with proteins, Inner layer has cristae. ATP synthesis takes place on inner membrane
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peroxisomes
small, round organelle that contains H2O2, oxidizes fatty acids and amino acids, detoxifies poisons, in liver cells
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glycosomes
specialized peroxisomes in plants, are responsible for converting fat into sugars
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vesicles
small, membrane-bound sac that functions in cellular storage and transport. Its membrane is capable of fusing with the plasma membrane and membranes of the ER and GA
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vacuoles
membrane-bound sac, somewhat larger than a vesicle, functions in cellular transport and storage, does not fuse with membranes of other organelles
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centrosome
region in animal cells made of 2 centrioles that serves as an organizing center for microtubules. Replicates itself after a cell divides, consists of two centrioles
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centriole
cylinder comprised of nine triplets of microtubules. Nontubulin proteins hold triplets together, have a role in pulling duplicated chromosomes
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lysosomes
animal cell's garbage disposal, functions as the cell's digestive component by breaking down proteins, lipids, other molecules
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cell wall
covering comprised of various molecules that protects the cell, provides structural support and gives shape to the cell. Made of peptidoglycan and cellulose
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chloroplasts
have own DNA and chromosomes, carry out photosynthesis, have inner and outer membranes
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thylakoids
fluid-filled membrane sacs, each stack is a granum, interconnected and stacked w/in inner membrane
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stroma
fluid enclosed by the inner membrane that surrounds the grana
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chlorophyll
green pigment in chloroplasts that captures the light energy that drives light reactions of photosynthesis, in thylakoid
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photosynthesis
Series of reactions that convert light energy, water, and CO2 into glucose and give off oxygen
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central vacuole
plays a key role in regulating the cell's concentration of water in changing environmental conditions. Regulates plant cell's storage, holds H2O, plays significant role in cell growth because is site of macromolecule degredation, used to maintain pressure
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endomembrane system
a group of membranes and organelles in eukaryotic cells that works together to modify, package, and transport lipids and proteins
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Endomembrane system contains:
nuclear envelope, endoplasmic reticulum, golgi apparatus, lysosomes, vacuoles and the plasma membrane.
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endoplasmic reticulum
a series of interconnected membranous structures within eukaryotic cells that collectively modify proteins and synthesize lipids. Rough ER and smooth ER. ER membrane is continuous with nuclear envelope
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Rough endoplasmic reticulum
region of the endoplasmic reticulum that is studded with ribosomes and engages in protein modification and phospholipid synthesis, abundant in cells that secrete proteins
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Smooth endoplasmic reticulum
continuous with RoughER, has few ribosome units on cytoplasmic surface. Functions in the synthesis of carbs, lipids, steroid hormones, and detoxification of meds
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sarcoplasmic reticuulm
special SER in muscle cells, responsible for storing Ca ions that are needed to trigger muscle cells coordinated contractions
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Golgi apparatus
eukaryotic organelle comprised of a series of stacked membranes that sorts, tags, and packages lipids and proteins for distribution. Series of flattened membranes.
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Fluid mosaic model
model that describes the arrangement and movement of the molecules that make up a cell membrane as a mosaic of phospholipids, cholesterol, proteins, glycoproteins, and glycolipids resulting in fluidity
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Phospholipds are amphiphilic
molecule possesses a polar or charged area capable of interacting with hydrophobic and hydophilic environments Are first major component
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integral proteins
protein integrated into the membrane structure that interacts extensively with the membrane. Lipids and hydrocarbon chains and often spans the membrane (goes all the way across both layers of phospholipid bilayer)
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peripheral proteins
protein at the plasma membrane's surface either interior or exterior, may serve as enzymes, structure, or part of cell recognition sites
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carbohydrates
3rd major component of plasma membrane, always on cell's exterior surface and bound to lipids or proteins
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Glycocalyx
carb components of glycolipids and glycoproteins, highly hydrophilic, attracts large amounts of H2O to cell's surface
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cholesterol
only in animal cells. is a binder that acts bidirectionally, increases fluidity as low temps and decreases fluidity at high temps. Acts as a buffer. Stiff region stops fatty acids from coming apart and lysing at high temperature. Fluid region (H-C tail) has enough interaction to stop fatty acid's tails from sticking together in cold temperatures
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Plasma Membranes Functions
1. dREefine outer border of all cells and organelles 2. Manage what enters and exits the cell 3. Receive external signals 4. Initiate cellular responses 5. Adhere to neighbors doing cells and exchange matter
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More ___ fat in tropics
saturated
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passive transport
method of transporting material through a semipermeable membrane, DOES NOT REQUIRE ENERGY. Substances move from high concentration to low concentration
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Oligosaccharides
on exterior of cell membrane, deal in cell communication
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Materials that can easily slip through membrane:
non-polar, lipid soluble low weight. Vitamins that are fat soluble, O2 and CO2 via simple diffusion.
passive, single substance moves from high concentration to low concentration, transports materials across membrane within a cell.
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filtration
variation of diffusion, material moves according to its concentration gradient through a membrane, enhanced by pressure
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facilitated diffusion/transport
process by which material moves down a concentration gradient using integral membrane proteins. Shields polar materials from membrane's repulsive forces
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transport proteins
membrane protein that facilitates a substances passage across a membrane by binding it, function as channels or carriers, transmembrane proteins
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channel proteins
membrane protein that allows a substance to pass through its hollow core across the plasma membrane. Have hydrophilic domains exposed intra and extracellular and hydrophobic channel through core
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aquaporins
channel protein that allows water through the membrane at a very high rate
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carrier proteins
embedded in plasma membrane, protein that moves a substance across the plasma membrane by changing its own shape, specific for a single substance. Finite number
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osmosis
the movement of free water through a semipermeable membrane according to the water's concentration gradient. Transports ONLY water. Will continue until the water's gradient goes to 0 or until the water's hydrostatic pressure balancces
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In osmosis, water moves
from high concentration of water molecules to low concentration of water molecules
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tonicity
amount of solute in a solution, describes how an extracellular solution can change a cell's volume by affecting osmosis, directly correlates with osmolarity
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tonicity is the
relationship between outside and inside the cell
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osmolarity
the total amount of substances dissolved in a specific amount of solution
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low osmolarity means
A greater water concentration relative to concentration of solute
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high osmolarity me ants
A lower water concentration relative to concentration of solute
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hypotonic
when comparing two solutions, the solution with the lesser concentration of solutes
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hypertonic
when comparing two solutions, the solution with the greater concentration of solutes
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isotonic
when the concentration of two solutions is the same
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osmoregulation
living thing's way of controlling effects of osmosis (plants have a cell wall)
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turgor pressure
The pressure that water molecules exert against the cell wall
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contractile vacuole
The cell structure that collects extra water from the cytoplasm and then expels it from the cell, in paramecia and amoebas
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active transport
requires cell's energy, usually in ATP form
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electrochemical gradient
a combined chemical and electrical force that produces a gradient, pushed molecules from low concentration to high concentration.
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protein pump
active transport mechanism that works against electrochemical gradients
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primary active transport
Active transport that relies directly on the hydrolysis of ATP. Ex= sodium potassium pump
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secondary active transport
movement of material that is due to the electrochemical gradient established by primary active transport
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transporter
specific carrier proteins or pumps that facilitate movement. Uniporter, symporter, antiporter
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endocytosis
type of active transport that moves substances into a cell. The membrane invaginates, forming a pocket around the target particle. The pocket pinches off resulting in the particle containing itself in a new intracellular vesicle
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phagocytosis
"cell eating", takes in large particles (anything but water)
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clathrin
protein that coats the inward-facing surface of the plasma membrane and assists in the formation of specialized structures, like coated pits, for phagocytosis
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pinocytosis
"cell drinking". Imports macromolecules that the cell needs from extracellular fluid, takes in molecules including water
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potocytosis
variation of pinocytosis that uses caveolin
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caveolin
protein that coats the cytoplasmic side of the plasma membrane and participates in the process of liquid update by potocytosis
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receptor-mediated endocytosis
The movement of specific molecules into a cell by the inward budding of membranous vesicles containing proteins with receptor sites specific to the molecules being taken in; enables a cell to acquire bulk quantities of specific substances.
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exocytosis
process of passing bulk material out of a cell into the extracellular fluid
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Cytosleleton
helps the cell maintain its shape, helps the cell move, helps organelles within the cell move
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microfilaments
the cytoskeletons' narrowest element, provides rigidity and shape to the cell and enables cellular movements
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intermediate filaments
Threadlike proteins in the cell's cytoskeleton that are roughly twice as thick as microfilaments. Bears tension, supports cell-cell junctions, anchors cell to extracellular structures. No role in cell movement
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microtubules
small, hollow tubes, the widest element, helps the cell resist compression, provides a track along which vesicles move through the cell, pulls replicated chromosomes to opposite ends. Comprised of alpha and beta tubulin
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cilia
Hairlike projections that extend from the plasma membrane and are used for locomotion
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extracellular matrix
The substance in which animal tissue cells are embedded, consisting of protein and polysaccharides.
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Human body cells have how many chromosomes?
46, 23 pairs
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diploid
A cell containing two sets of chromosomes (2n), one set inherited from each parent.