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plasma membrane
separates the living cell from its surroundings. Controls traffic in and out of the cell. Is selectively permeable.
selectively permeable
allows some substances to cross more easily than others.
phospholipids
most abundant lipids
lipids and proteins
main macromolecules in membranes
amphipatic molecules
have hydrophobic and hydrophilic regions
fluid mosaic model
The arrangement of phospholipids and proteins in biological membranes is described by the...
freeze-fracture
preparation technique that splits a membrane along the middle of the phospholipid bilayer
transmembrane proteins
the integral protein completely spans the membrane as...
integral proteins
proteins that penetrate the hydrophobic interior of the lipid bilayer
peripheral proteins
proteins that are not embedded in the lipid bilayer
cell-cell recognition
the ability of a cell to disitnguish one type of neighboring cell from another.
supramolecular structure
many molecules ordered into a higher level of organization with emergent properties than those of the individual molecules.
transport proteins
proteins that span the membrane.
channel proteins
transport proteins that have a hydrophilic channel that certain molecules or ions use as a tunnel though the membrane.
aquaporins
channel proteins that facilitate the passage of water
carrier proteins
transport proteins that bind to molecules and change shape to shuttle them across the membrane.
diffusion
movement of molecules of any substance to spread out in available space
concentration gradient
the region along which the density of a chemical substance increases or decreases.
passive transport
transport that requires no energy from the cell to make it happen
osmosis
the diffusion of water across a selectively permeable membrane
tonicity
the ability of a surrounding solution to cause a cell to gain or lose water.
isotonic (animal cell)
if a cell with no cell wall is immersed in an enviroment where there is no net movement of water across the plasma membrane. Stays the same.
hypertonic (animal cell)
when the cell is immersed in a solution where it loses water to its environment, shrivels and probably dies.
hypotonic (animal cell)
when a cell is immersed in a solution, water enters the cell faster than it leaves, it swells and lyses (explodes) like an overfilled water balloon.
osmoregulation
the control of water balance
Paramecium
is a protist that is hypertonic to the pond water in which it lives.
turgid
when the plant cell is very firm, which is a healthy state for most plant cells.
hypotonic (plant cell)
when a plant cell is immersed in a __________ solution the cell contents swell due to osmosis until the elastic cell wall exerts turgor pressure on the cell that opposes further water outake.
isotonic (plant cell)
when a plant cell is immersed in a _______ solution; there is no net movement. The cell becomes flaccid and the plant may wilt.
flaccid
limp, not firm or strong (If a plant is not watered enough, its leaves become droopy and flaccid.)
hypertonic (plant cells)
the plant cell loses water, its volume shrinks. The plasma membrane pulls away from the wall, this is plasmolysis. It is lethal to the cell.
plasmolysis
This happens when a cell shrinks inside its cell wall while the cell wall remains intact. The plasma membrane pulls away from the wall.
facilitated diffusion
the passive movement of molecules down their concentration gradient with the help of transport proteins.
ion channels (gated channels)
Channels that open or close depending on the presence or abscence of an electrical, chemical, or physical stimulus.
cystinuria
human disease characterized by the absence of a carrier protein that transports cysteine and other amino acids across the membranes of kidney cells.
active transport
transport that requires the cell to expend metabolic energy and enables a cell to maintain internal concentrations of small molecules. Requires energy.
ATP
supplies energy for most active transport
sodium-potassium pump
transport protein that, translocating the bound solute across the membrane. Exchanges sodium ions (Na) for potassium ions (K) across the plasma membrane of animal cells.
membrane potential
voltage across a membrane. Ranges form -50 to -200 millivolts. The inside of the cell is negative to the outside.
electrochemical gradient
2 combined forces drive the diffusion of ions across the membrane.
electrogenic pumps
special transport proteins that generate the voltage gradient across a membrane.
Ex. sodium potassium pump and proton pumps.
sodium-potassium pump
major electrogenic pump in animals. Restores the electrochemical gradient by setting up a concentration gradient. It pumps 2 K ions for every 3 Na ions that it moves out, it generates a voltage.
proton pumps
the major electrogenic pump. Transports protons out of the cell and transfers positive charge form the cytoplasm to the extracellular solution.
cotransport
single ATP-powered pump that transports a specific solute can indirectly drive the active transport of several other solutes in a mechanism.
exocytosis
transport vesicle budded from the Golgi apparatus is moved by the cytoskeleton to the plasma membrane. When the 2 membranes come in contact, the bilayers fuse spill the contents.
endocytosis
a cell brings in biological molecules and particulate matter by forming new vesicles from the plasma membrane.
3 types: phagocytosis, pinocytosis and receptor-mediated endocytosis.
phagocytosis
a cell engulfs a particle in a vacuole. The vacuole fuses with a lysosome to digest the particle.
pinocytosis
molecules are taken up when extracellular fluid is "gulped" into tiny vesicles.
receptor-mediated endocytosis
endocytosis that enables a cell to acquire bulk quantities of specific materials that may be in low concentrations in the environment.
lipoproteins
complexes of proteins and lipids. Cholesterol travels in low density _______
ligands
A molecule that binds specifically to a receptor site of another molecule.
dialysis
movement of particles in a solution through permeable membranes. The diffusion of small solutes through a selectively permeable membrane.
organelles
membrane-enclosed structures within a eukaryotic cell
cytosol
a jellylike substance where organelles and other components are found
eukaryotic cell
Cell with a nucleus and membrane bound organelles
prokaryotic cell
Cell with no nucleus nor membrane bound organelles
nucleoid region
a non-membrane-enclosed region of the cell where prokaryotic DNA is found
cytoplasm
the region in a cell between the cell membrane and nucleus; it contains the cell structures and oganelles
plasma membrane
The selective barrier that surrounds a cell; it controls what enters and leaves the cell
nucleus
chromosome-containing part of a eukaryotic cell
nuclear envelope
encloses the nucleus to separate its contents from the cytoplasm
nuclear lamina
a netlike array of protein filaments that maintains the shape of the nucleus by mechanically supporting the nuclear envelope, lines the nuclear side of the nuclear envelope
chromosomes
tightly coiled structures that carry the genetic information (can be seen during nuclear division)
chromatin
loosly coiled genetic material that makes up chromosomes, a complex of proteins and DNA
nucleolus
located in the nucleus, makes, synthesizes, and partially assembles ribosomes
ribosomes
made of ribosomal RNA and protein, synthesize proteins
endomembrane system
membranes that divide the cell into organelles such as the nuclear membrane, the endoplasmic reticulum, the Golgi apparatus, lysosomes, vesicles, and the cell membrane.
endoplasmic reticulum (ER)
accounts for more than half of total membrane in many eukaryotic cells, continuous with the nuclear envelope
smooth ER
portion of the endoplasmic reticulum free of ribosomes, synthesize lipids, detoxifies the cell, and regulates calcium levels
rough ER
portion of the endoplasmic reticulum studded with ribosomes, produce and transport membrane and secretory proteins
glycoproteins
proteins with covalently-bonded carbohydrates that play a role in cell to cell interaction
transport vesicles
vesicles in transit from one part of the cell to another
Golgi apparatus
stack of membranes that modifies, sorts, and packages proteins from the endoplasmic reticulum
lysosome
membranous sac of hydrolytic enzymes, which the cell uses to digest unwanted materials
phagocytosis
the process by which a cell engulfs a solid particle
autophagy
lysosomes break down damaged organelles
food vacuoles
formed by phagocytosis, pinches off from plasma membrane and encloses a food particle
contractile vacuoles
pump excess water out of the cell to maintain a suitable concentration of ions and molecules in the cell
central vacuole
the largest organelle in a plant cell. It is surrounded by the tonoplast and functions to hold materials and wastes. It also functions to maintain the proper pressure within plant cells
mitochondria
chemically convert chemical (food) energy into usable ATP energy through cellular respiration
chloroplasts
contain chlorophyll which help absorb solar energy in order to convert carbon dioxide and water into sugars during photosynthesis
cristae
infoldings in the inner membrane of the mitochondria
mitochondrial matrix
compartment of the mitochondrion, enclosed by the inner membrane, contains enzymes and substrates for the citric acid cycle
plastids
manufacture and store important chemical compounds used by the cell such as pigments, oils, and starches
thylakoids
flattened and interconnected sacs found in chloroplasts. The light dependent stage of photosynthesis occurs on the membranes of these sacs
granum
stacks of thylakoids
stroma
fluid outside the thylakoids, contains chloroplast DNA, ribosomes, and enzymes. The light independent stage of photosynthesis occurs in this area
cytoskeleton
a network of fibers bracing the cytoplasm
microtubules
hollow rods of protein, support the cell and moves organelles within the cell
centrosome
a region located near the nucleus where micro-tubules grow from; important in cell division
centrioles
cylindrical organelle near the nucleus in animal cells, occurring in pairs and involved in the development of spindle fibers in cell division
flagella
a long tail-like structure that aids in cell movement
cilia
a short hair-like structures that enable movement of cells or movement of materials outside a cell, utilizes a back-and-forth motion
microfilaments
the thinnest part of the cytoskeleton, are used to give shape to the cell and support all of its internal parts
actin
a globular protein that makes up microfilaments
pseudopodia
cellular extensions that enable a cell to crawl along a surface
cytoplasmic streaming
the circular flow of cytoplasm within cells
intermediate filaments
diverse class of cytoskeletal elements that bear tension like microfilaments
cell wall
extracellular structure specific to plant cells, protects the cell, maintains its shape, and prevents excessive water uptake
primary cell wall
a relatively thin and flexible layer in plant cells, first secreted by a young cell