Select all of the following that are metabolic waste products.
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Urea is a waste product of
amino acid metabolism.
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After ammonia is produced from amino acid breakdown, the liver quickly combines it with carbon dioxide to produce
urea
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Select all common symptoms of uremia.
vomiting
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Which system plays a major role in salt, water, and pH homeostasis of the blood
urinary
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Ammonium, creatinine, urea, and uric acid are what type of metabolic waste?
nitrogenous
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The primary nitrogenous end product of metabolism in humans is__________ which is a waste product of amino acid metabolism.
urea
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The organ that converts ammonia from amino acid breakdown to the less toxic compound urea is the
liver.
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The condition caused by elevated urea levels in the blood ls called
uremia
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What are the major roles of the urinary system?
maintaining salt balance of the blood
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Creatinine is a waste product that results from the breakdown of
creatine phosphate.
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The breakdown of nucleotides produces which nitrogenous waste product?
uric acid
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If uric acid levels are so high that crystals precipitate and collect in the joints, the result is a painful condition called
gout
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What is uremia caused by?
high urea levels in the blood
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The kidneys affect blood pressure mainly by
regulating sodium and potassium levels.
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Creatine phosphate is used as an energy reserve in muscles. When broken down, creatine forms
creatinine.
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The breakdown of nucleotides forms _________ acid
Uric
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Gout is a painful condition that results from an accumulation of what chemical in the joints?
Uric Acid
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Select all correct descriptions of the human kidneys.
humans normally have two kidneys
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By regulating levels of sodium and potassium ions in the blood, the kidneys influence
blood pressure
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What structure transports blood away from a kidney?
renal vein
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Each human kidney is covered by a renal capsule made of
fibrous connective tissue.
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The breakdown of nucleotides produces which nitrogenous waste product
uric acid
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Arrange these three layers of the wall of a ureter from the innermost layer (on top) to the outermost layer (on the bottom).
Mucosa
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The kidneys lie in depressions posterior to the
peritoneum.
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The main function of the urinary bladder is to
store urine
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A renal ________ delivers blood to the kidney for filtration.
artery
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Each human kidney is covered by a layer of fibrous connective tissue called the renal
capsule
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Urine passes out of a kidney and through a _________ on its way to the urinary bladder.
ureter
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Select all correct descriptions of the urinary bladder.
two ureters enter
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True or false: Once the urinary bladder fills with urine, stretch receptors are activated and urination occurs involuntarily.
False
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The main function of the ureters is to
transport urine
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Similar to the stomach, the inner layer of the urinary bladder wall has deep folds called ________ that disappear as the bladder fills
rugae
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The maximum capacity of the urinary bladder of an adult human is approximately
750-800 ml
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When you decide to urinate, what will happen?
The bladder contracts.
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Urine passes out of a kidney and through a _______ on its way to the urinary bladder.
ureter
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The bladder wall contains how many layers of smooth muscle?
3
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As urine exits the body, it passes from the urinary bladder and out via the
urethra
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Urine cannot escape back into the ureter from the bladder due to the presence of
small folds of bladder mucosa.
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Of the three regions of a human kidney, which is the innermost layer?
renal pelvis
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True or false: Each nephron has its own blood supply.
True
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Place the renal circulatory vessels in the correct order as blood would pass through them, with the vessel that brings blood into the kidney at the top.
1. Renal artery
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What is the main function of the urethra?
expel urine
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As it carries blood away from a glomerulus, the efferent arteriole divides and forms the _______ capillary network, which surrounds the rest of the nephron.
peritubular
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The knot of capillaries in a nephron where blood is filtered is called the
glomerulus.
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Blood leaves each glomerulus in which of the following?
efferent arteriole
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The leader labeled "A" is pointing to the _______ convoluted tubule
proximal
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In each nephron, the _______ arteriole divides to form the peritubular capillary network.
efferent
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What is the glomerular capsule?
a cup-like structure composed of epithelial cells
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Select all correct descriptions of the proximal convoluted tubule.
location of reabsorption
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Which component of a nephron receives fluid from the proximal convoluted tubule?
loop of the nephron
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Identify the component of the nephron labeled with the letter A. (Circle)
glomerulus
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The closed end of a nephron forms a cuplike structure called a Bowman's or _______ capsule.
glomerular
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Which component of a nephron receives the glomerular filtrate directly from the glomerular capsule?
proximal convoluted tubule
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Which part of the loop of the nephron actively transports salts from the filtrate to interstitial tissues?
ascending limb
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What is the first step of urine formation?
glomerular filtration
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The function of the brush border in the proximal convoluted tubule is to
increase surface area
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What structure in the nephron has the primary function of allowing water to diffuse into the tissue fluid surrounding the nephron?
loop of nephron
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Identify the component of the nephron indicated by the letter A. (Brown tube coming from cirlcle)
proximal convoluted tubule
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Select the three main processes in urine formation.
tubular reabsorption
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In which part of the nephron does filtration takes place?
glomerulus
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During the process of urine formation, molecules and ions are passively and actively reabsorbed from the the glomerular filtrate back into the blood of the peritubular capillary network. This is called tubular
reabsorption
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Where does tubular secretion occur?
along the length of the kidney tubule
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What forces filtration at the glomerular capsule?
an increase in glomerular blood pressure
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True or false: Human kidneys play a limited role in overall homeostasis, mainly related to the excretion of nitrogenous wastes.
False
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Select the types of nitrogenous waste that are excreted by human kidneys.
creatinine
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What follows from the fact that reabsorption of salt increases the osmolarity of the blood compared with the filtrate?
Water moves passively from the tubule into the blood.
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What happens during tubular secretion?
Substances are removed from blood and added to the tubular fluid.
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Water channels within plasma membranes are called
aquaporins
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What percentage of sodium in the glomerular filtrate is normally returned to the blood by the kidneys?
99%
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How do the kidneys contribute to homeostasis?
maintain acid-base balance
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The cardiovascular system carries nitrogenous wastes to the kidneys, which excrete them from the body in the fluid called
urine
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Aquaporins are channels that allow _______ to travel across plasma membranes.
water
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What process returns water to the blood from the filtrate?
osmosis
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Ion exchange at the distal convoluted tubule is affected by the adrenal gland hormone called
aldosterone
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What causes the release of renin from the juxtaglomerular apparatus?
decreased blood pressure
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Select all of the following that describe renin.
regulated by blood pressure
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regulates aldosterone
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Select all of the hormones associated with kidney function.
aldosterone
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The major effect of aldosterone on the kidneys is to promote
sodium ion reabsorption and potassium ion excretion by the distal convoluted tubules
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The _______ is a region of contact between the afferent arteriole and the distal convoluted tubule.
juxtaglomerular apparatus
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Renin is an enzyme secreted by the
kidney
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On the diagram highlighting the juxtaglomerular apparatus of the nephron, the structure labeled "A" is the _______ convoluted tubule. (brown hole thing under the circle thing)
distal
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What happens after alcohol consumption reduces the secretion of ADH in the posterior pituitary?
a large amount of dilute urine is produced
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When blood volume increases to the point that cardiac cells are stretched, the heart releases _______ natriuretic hormone.
atrial
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Match the hormone with its function.
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Which substance is actively transported out of the ascending limb of the loop of the nephron?
sodium chloride
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What category of drug increases urinary output?
diuretic
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An increase in blood osmolarity causes the hypothalamus to produce the hormone ADH, or _______ hormone.
antidiuretic
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Which hormone is secreted by cardiac cells in response to high blood volume?
atrial natriuretic hormone
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Water is absorbed from what part of the loop of the nephron?
descending limb
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The term _______ refers to when the pH of the blood drops below normal while _______ refers to a blood pH above normal.
acidosis; alkalosis
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One of the most important buffers in the blood is a combination of carbonic acid with what?
bicarbonate ions
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Chemicals or drugs that increase urine production are called
diuretic
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Select all of the ways in which the kidneys assist other body systems.
regulate the sodium ions and potassium ions for nerve conduction
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An infection or inflammation of the urethra is called _____
urethritis
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True or false: When blood pH is above 7.45 a person is said to have acidosis.
false
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Carbonic acid and bicarbonate ion are _______ that can maintain appropriate hydrogen ion concentration of the blood.
buffers
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What hormone produced by the kidneys can be used to stimulate red blood cell production in patients in renal failure or recovering from chemotherapy?
erythropoietin
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As salt concentration in the body fluid increases, osmoreceptors signal a(n) increase in the release of ADH from the posterior _______ gland.