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204 Terms
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What are the functional categories of nutrients and which nutrients fall under those categories?
Functional Categories: primarily provide energy important for growth and development regulate body processes and keep functions running smoothly Nutrients that fall under these categories: carbohydrates, protein, lipids/fat, vitamins, minerals, and water
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What other ways are nutrients categorized and at what levels?
Macronutrients: nutrients needed in large quantities (carbs, protein, lipids/fats) Micronutrients: vitamins and minerals are needed in such small amounts in the diet
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What are the functions of micronutrients?
vitamins and minerals are needed in such small amounts in the diet vitamins enable many chemical reactions to occur in the body help release energy trapped in carbs, lipids, and proteins
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What is the general chemical structure of different nutrients? (organic vs. inorganic)
organic compounds: substance that contains carbon atoms bonded to hydrogen atoms in the chemical structure inorganic compounds: lack carbon atoms bonded to hydrogen atoms
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Define Appetite vs. Hunger. How does each influence our desire to eat?
hunger: primarily physiological (internal) drive to find and eat food, mostly regulated by internal cues to eating Appetite: primarily psychological (external) influence that encourages us to find and eat food, often in the absence of obvious hunger
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Basic functions of nutrients (growth, structure etc.)
They are the main source of energy for the body. They help in building and repairing body tissues. Increases the absorption of fat-soluble vitamins. Helps in the synthesis of collagen. Provides proper structure to the blood vessels, bones and ligaments. They also help in maintaining the homeostasis of the body.
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What type of improvements can be made in the typical American diet?
treat food as medicine focus on quality of calories, not just quantity expand access to dietary and lifestyle counseling support food entrepreneurs increase the number of new farmers growing healthy foods using regenerative farming techniques make school meals free for all students establish a federal “food czar”
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Dietary Guidelines for Americans – purpose and key recommendations
reduce the risk of obesity, hypertension, cardiovascular disease, type 2 diabetes, osteoporosis, alcoholism, and foodborne illness
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MyPlate: basic messages including foods to increase and reduce
MyPlate focuses on these key behaviors Balancing Calories Enjoy your food, but eat less Avoid oversized portions Foods to Increase Make half your plate fruits and vegetables Make at least half your grains whole grains Switch to fat free (skim) or low fat (1%) milk Foods to Reduce Compare sodium in foods like soup, bread, and frozen means and choose foods with lower numbers Drink water instead of sugary drinks
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What is the difference between RDA and AI?
Recommended Dietary Allowance (RDA): the dietary intake level that is sufficient to meet the nutrient requirement of nearly all healthy individuals in a particular life stage and gender group Adequate Intake (AI): a recommended intake value based on observed or experimentally determined approximations or estimates of nutrient intake by a group of healthy people that is assumed adequate; used when an RDA cannot be determined. An AI is the average amount of a nutrient needed, and an RDA is the minimum amount needed per day.
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Where are different nutrients absorbed?
Stomach: Alcohol (20%) and water (minor amount) Small Intestine: calcium, magnesium, iron, and other minerals glucose amino acids fats vitamins water (70 to 90% of total) alcohol (80%) bile acids Large Intestine sodium potassium some fatty acids vitamin K and biotin (synthesized by microorganisms in the LI) gases water (10-30%)
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Define peristalsis.
the process by which food is mixed with digestive secretions and propelled down the GI
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What is the site in the GI tract where most digestion takes place?
small intestine
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What is the storage form of glucose? What is its function?
glycogen is the storage form of glucose When the body needs a quick boost of energy or when the body isn't getting glucose from food, glycogen is broken down to release glucose into the bloodstream to be used as fuel for the cells.
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What is dietary fiber?
fiber in food, includes the parts of plant foods your body can't digest or absorb.
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What are the different ways the body can produce glucose?
The liver supplies sugar or glucose by turning glycogen into glucose in a process called glycogenolysis. The liver also can manufacture necessary sugar or glucose by harvesting amino acids, waste products and fat byproducts. This process is called gluconeogenesis.
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What are the risk factors and treatments for diabetes?
Type 1 Autoimmune Occurs more often in children Body stops producing insulin Treatment Insulin therapy Diet therapy Type 2 Generally, in people > 40 years of age Increasing rates in younger individuals Obesity Treatment Weight loss oral medication Diet therapy Insulin: hormone produced by beta cells of the pancreas. Among other processes, insulin increases the synthesis of glycogen in the liver and the movement of glucose from the bloodstream into muscle and adipose cells
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What are the functions of protein in the body?
proteins form important structures in the body, make up key part of blood, help regulate body functions, can fuel body cells
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If an amino acid is unavailable for protein synthesis, what occurs?
synthesis of the protein will stop and be limited
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Define the biological value of a food protein.
Biological value measures protein quality by calculating the nitrogen used for tissue formation divided by the nitrogen absorbed from food.
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What are complementary proteins?
two food protein sources that make up for each others inadequate supply of specific essential amino acids → together they yield a sufficient amount of all nine and so provide high quality complete protein for the diet
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Describe food combinations that yield complete proteins
Nuts or seeds with whole grains (peanut butter on whole wheat toast) Whole grains with beans (beans and rice; hummus and pita bread)
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What affects protein quality?
Food protein quality is traditionally dependent on its amino acid content and the availability of these amino acids in circulation
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What is positive nitrogen balance? Negative nitrogen balance?
when protein intake is less than that lost, an individual is in negative protein balance when protein intake is greater than losses a state of positive balance is attained
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What are the functions of fatty acids in the body?
Immune system functions and vision Help form cell membranes Produce eicosanoids, which are involved in practically all important functions in the body
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What do trans fatty acids do to cholesterol? Raise or lower? Which type of cholesterol?
Trans fats increase LDL cholesterol and decrease HDL cholesterol, which can increase the risk of heart attack or stroke.
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Describe the Mediterranean diet.
Olive oil as the main fat ∙ Abundant daily intake of fruits, vegetables (especially leafy greens like purslane, which is high in omega-3 fatty acids), whole grains, beans, nuts, and seeds ∙ An emphasis on minimally processed and, wherever possible, seasonally fresh and locally grown foods ∙ Daily intake of small amounts of cheese and yogurt ∙ Weekly intake of low to moderate amounts of fish ∙ Limited use of eggs and red meat ∙ Regular exercise ∙ Moderate drinking of wine at mealtime
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What are the functions of cholesterol in the body?
Your body needs some cholesterol to make hormones, vitamin D, and substances that help you digest foods. Your body makes all the cholesterol it needs.
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Where does digestion of lipids occur?
The digestion of lipids begins in the oral cavity through exposure to lingual lipases, which are secreted by glands in the tongue to begin the process of digesting triglycerides. Digestion continues in the stomach through the effects of both lingual and gastric enzymes.
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What is the major fat-digesting enzyme?
Lipase is the major enzyme that breaks down dietary fats into smaller molecules called fatty acids and glycerol. This is done when lipase hydrolyzes lipids, the ester bonds in triglycerides.
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What is a lipoprotein?
a compound in bloodstream containing a core of lipids with shell composed of protein, phospholipids, and cholesterol
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Function of lipoprotein?
fulfilling their major physiological role of bulk lipid transport, help maintain the lipid composition of cell membranes, and directly influence several cellular biochemical reactions.
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What are the benefits and risks associated with alcohol consumption?
Alcohol abuse can lead to poor nutritional status and development of nutrient deficiencies Alcohol may replace food in the diet If relied on for majority of energy needs, protein energy malnutrition develops, with symptoms similar to kwashiorkor Moderate alcohol intake may: Reduce stress and anxiety Episodically Stimulate appetite and increase dietary intake in elderly Lower risk of cardiovascular disease
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What are the recommendations for at risk sub groups related to alcohol consumption?
For people who are not pregnant, and those older than age 65: No more than three drinks on any single day, and no more than seven drinks per week. For males up to age 65 years: No more than four drinks on any single day, and no more than 14 drinks per week.
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What are the signs and symptoms of alcohol abuse?
Experiencing temporary blackouts or short-term memory loss Exhibiting signs of irritability and extreme mood swings Making excuses for drinking such as to relax, deal with stress or feel normal Choosing drinking over other responsibilities and obligations Becoming isolated and distant from friends and family members Drinking alone or in secrecy Feeling hungover when not drinking Changing appearance and group of acquaintances you hang out with
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Define hunger and appetite.
hunger: primarily physiological (internal) drive to find and eat food, mostly regulated by internal cues to eating Appetite: primarily psychological (external) influence that encourages us to find and eat food, often in the absence of obvious hunger
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What is metabolism?
the chemical reactions in the body's cells that change food into energy. Our bodies need this energy to do everything from moving to thinking to growing. Specific proteins in the body control the chemical reactions of metabolism. metabolic pathways → Glycolysis, fatty acid synthesis, and glycogen synthesis happen in the cytoplasm, along with some steps of amino acid breakdown. Several metabolic pathways are in specific locations inside of mitochondria.
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What is ATP?
Adenosine triphosphate (ATP) is the source of energy for use and storage at the cellular level. The structure of ATP is a nucleoside triphosphate, consisting of a nitrogenous base (adenine), a ribose sugar, and three serially bonded phosphate groups.
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How are amino acids metabolized to produce energy?
Transamination: the pathway allows cells to synthesize nonessential amino acids deamination: the pathway allows for loss of an amino group without transferring it to another carbon skeleton
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What are the physiological effects of fasting at short, intermediate, and long time periods?
In the first few hours of a fast, the body fuels itself with stored liver glycogen and fatty acids and adipose tissue As it prolongs body fat continues to be broken down and live glycogen becomes exhausted First Few days: body protein is broken down rapidly → supplies 90% of needed glucose sodium and potassium depletion also can result during fasting after several weeks of fasting world or more of the nervous systems energy needs are met by ketone bodies
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What conditions lead to ketosis?
Severe carb restriction can cause your body to break fat down into ketones for energy. This is called ketosis. Ketosis can cause side effects such as bad breath, headache, fatigue and weakness. It's not clear what kind of possible long-term health risks a low-carb diet may pose.
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What are the different pathways for alcohol metabolism and when do they occur?
Alcohol requires no: Digestion Specific transport mechanisms Receptors Rapidly absorbed through GI tract by simple diffusion Carbonation increases rate of absorption Stomach absorbs 20% Remained absorbed in small intestine 1. Alcohol Dehydrogenase (A D H) pathway Low to moderate intakes 2. Liver activates microsomal ethonal oxidizing system (M E O S) to help During moderate to excessive alcohol intake, A D H pathway cannot keep up As intake increases overtime, M E O S is more active Allows for efficient metabolism and greater tolerance More alcohol is required to produce same effects Capacity for drug metabolism is decreased 3. Catalase Pathway Minor contribution to alcohol metabolism
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Describe how the body prioritizes energy production from macronutrients and the different fates of macronutrients when metabolized.
Macronutrients are rich sources of energy because carbs, proteins, and fats are interrelated and serve as fuel for body cells. cells release the energy in carbs and capture it as ATP and triglycerides fatty acids used to generate energy can come from triglycerides The answer lies in the coupling between the oxidation of nutrients and the synthesis of high-energy compounds, particularly ATP, which works as the main chemical energy carrier in all cells.
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How is metabolism regulated?
when it comes to regulating these metabolic pathways, the liver plays the major role because it responds to hormones and makes use of vitamins additional means of regulating metabolism involve ATP concentrations, enzymes, hormones, vitamins, and minerals
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What are the main differences between aerobic and anaerobic metabolism?
Aerobic metabolism is the process of extracting energy from carbohydrate sources such as fatty acids, amino acids. Anaerobic metabolism, which can be defined as ATP production without oxygen (or in the absence of oxygen), occurs by direct phosphate transfer from phosphorylated intermediates, such as glycolytic intermediates or creatine phosphate (CrP), to ADP forming ATP. While aerobic metabolism generates more ATP and relies on oxygen, anaerobic metabolism does not need oxygen but only creates two ATP molecules per glucose molecule. However, anaerobic and aerobic metabolism are both required to produce cellular energy.
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What happens to different macronutrients when in a feasted state?
fat consumed in excess of needs goes immediately into storage adipose cells high fat, high energy diets promote the accumulation of body fat excess of protein can reside in amino acid pools in the body carbs consumed in excess of need is used first to maximize glycogen stores → carb consumption stimulates the use of carbohydrate as fuel and storage of excess amounts as body fats
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What are inborn errors of metabolism?
Caused by the lack of a specific enzyme to preform normal metabolic functions and the metabolic pathway in which the enzyme is supposed to participate does not function normally can cause alternative metabolic products to be formed which can sometimes be toxic to the body inherited → gene carried by both parents and then passed on to child there is no cure but some control is offered phenylketonuria is the most common form
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Define set point theory
the set point theory proposes that humans have a genetically predetermined body weight or body fat content, which the body closely regulates
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What is energy balance?
energy balance is the relationship between energy intake and energy expenditure when the calories consumed from food and beverages (energy intake) match the amount of energy expended
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What is positive energy balance?
when energy output does not surpass energy intake
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What is negative energy balance?
when energy output surpasses energy intake
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What daily deficit of calories is needed to lose one pound per week?
~500 calories
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What contributes to total energy expenditure?
for a sedentary person basal metabolism accounts for about 60-70% of total energy expenditure physical activity, digestion, absorption, and processing of nutrients makes up the rest thermogenesis: the energy expended during fidgeting or shivering in response to cold contributes minorly to expenditure though
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What is BMR?
Basal metabolic rate represents the minimum amount of energy expended in a fasting state to keep a resting, awake body alive in a warm quiet environment.
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What affects BMR?
Increase BMR: Greater muscle mass Larger body surface area Male gender (males typically have more body surface area and muscle mass than females) Body temperature (fever or cold environmental conditions) Higher than normal secretions of thyroid hormones (a key regulator of basal metabolism) Aspects of nervous system activity (e.g., the release of stress hormones) Growth stages of the life cycle Caffeine and tobacco use (using tobacco to control body weight is not recommended because too many health risks are increased) Recent exercise Decrease BMR Lower than normal secretions of thyroid hormones (hypothyroidism) Restricted calorie intake Less body surface area and muscle mass Aging after age 30 years
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What is TEF?
thermic effect of food (TEF) is the energy the body uses to digest, absorb, transport, store, and metabolize nutrients accounts for 5-10% of all energy consumed each day large meals result in higher TEF values than the same amount of food eaten over many hours
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What factors influence obesity risk?
when a child has 1 obese parent, that risk rises 40% when 2 parents are obese its 80% aging: adults tend to gain weight as they age due to the slowing of basal metabolism female gender: women naturally have greater fat stores than men high calorie diet: excess energy intake, binge eating, preference for high energy dense foods sedentary lifestyle: a low or decreasing amount of physical activity favors weight gain weight history: overweight children & teens → increased risk of being overweight in adulthoods social and behavioral factors certain medications: stimulate appetite, causing food intake to increase geographic location genetic characteristics
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Define Body Mass Index (BMI)
Body mass index only evaluates an individual's height and weight. Body composition evaluates the breakdown of fat and fat free mass, giving a better estimate of fitness level and health risk.
When is BMI not an accurate predictor of obesity and overweight?
The limitation of BMI is that this measurement does not distinguish fat from muscle. According to some research, more than half of Americans have a normal BMI but a high body fat percentage, which is known as normal weight obesity. A person who has normal weight obesity is just as unhealthy as someone with a high BMI.
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What can be used instead of BMI to determine body fatness?
skinfold thickness is a common anthropometric method to estimate total body fat content accuracy of this method is good bioelectrical impedance: estimates body fat content by sending a painless, low energy electrical current through the body Dual Energy X-ray absorptiometry (DXA) is considered the most accurate way to determine body fat but the equipment is very expensive and not widely available
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How does body fat distribution indicate health risk?
Upper body obesity is more often related to cardiovascular disease, hypertension, and type 2 diabetes
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What the principles of a sound weight loss plan?
control of energy intake regular physical activity control of problem behaviors
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How is weight loss success defined?
weight loss success is defined as the ability to keep the weight off rather than gaining it back
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Where is appetite regulated?
the hypothalamus
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What are some behavior modification strategies for weight control?
chain breaking: separates the link between behaviors that tend to occur together stimulus control: alters the environment to minimize the stimuli for eating cognitive restructuring: changes ones from of mind regarding eating contingency management: prepares one for situations that may trigger overeating self monitoring: tracks which foods are eaten, when, why, how one feels etc..
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What are the characteristics of an appropriate weight-loss program?
rate of loss flexibility intake behavior modification overall health
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What are the treatments for morbid obesity?
Healthy eating plan and regular physical activity Changing your habits Weight-management programs Weight-loss medicines (drug treatment for weight loss) Weight-loss devices Bariatric surgery Special diets (Very-low calorie diets (VLCDs) Gastroplasty (stomach stapling → gastric bypass) gastric sleeve
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Why is prevention of eating disorders so important?
Without treatment, eating disorders can cause serious physical health complications, including heart conditions and kidney failure, which may even lead to death Disordered eating can escalate into physiological changes associated with sustained food restriction, binge eating, purging, and fluctuations in weight that interfere with everyday activities. It also involves emotional and cognitive changes that affect how people perceive and experience their bodies, such as feelings of distress or extreme concern about body shape or weight.31 Eating dis- orders frequently co-occur with other psychological disorders, such as depression, substance abuse, and anxiety disorders.
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Describe the strategies to treat and prevent eating disorders?
Self-help groups for those with eating disorders, as well as their families and friends, represent non threatening first steps into treatment. People also can attend self-help group meetings to get a sense of whether they really do have an eating disorder Nutrition Therapy Ultimately achieve and maintain weight gain Increase food intake to raise basal metabolism Prevent further weight loss Gain 2-3 pounds per week BMI goal of 20+ Restore appropriate food habits Restrict excessive activity Psychological therapy Pharmacological therapy
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What are the difference between anorexia and bulimia?
Anorexia Nervosa Three criteria Severely restrict energy intake relative to requirements Intense fear of gaining weight or becoming obese Very distorted body image Physical Effects of Anorexia Visible “Skin and Bone” appearance Rough, dry, scaly, cold skin Lanugo and loss of hair Loss of teeth Non-visible Slowed basal metabolism & HR lowered body temperature Nutrient deficiencies Low white blood cell count Bulimia Nervosa Bulimia means ravenous hunger Recurrent episodes of binge eating followed by some type of compensatory behavior to prevent weight gain Compensatory behaviors: actions take to rid body of excess calories and/or alleviate guilt, anxiety associated with binge; include vomiting, misuse of laxatives, or excessive exercise Likely many people with bulimic behavior never diagnosed
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What are the characteristics of vitamins?
body can't make enough to maintain health absence causes a deficiency that can be cured if vitamin is resupplied in time not a source of energy aid in energy metabolism, growth, development, and maintenance of body tissues
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What are the classifications of vitamins?
Fat Soluble vitamins water soluble vitamins
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What are the differences between fat-soluble and water-soluble vitamins?
water soluble vitamins dissolve in water Vitamins C and B and Choline Absorbed primarily in small intestine Transported to liver via portal vein and distributed to body tissues Tissue saturation fat soluble vitamins: dissolve in organic solvents such as ether and benzene Vitamins A,D,E,K Absorbed with dietary fat Anything interfering with fat absorption will impair fat soluble absorption Stored in fat
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What are the ways to preserve vitamin content when storing, preparing, or cooking foods?
The more ripe a fruit or vegetable is, the more vitamin content it has Freezing can help retain nutrients Often blanched first, increasing vitamin content Water soluble particularly susceptible to destruction by heat, light, air exposure, cooking in water and alkalinity
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How are fat soluble vitamins absorbed in the body?
Vitamins A, D, E, K
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What are the classifications of minerals?
Major: need 100 mg + per Trace: need less than 100 mg per day Ultratrace: trace amounts in diet, not essential to human health Nickel and cobalt
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Where are minerals absorbed in the body?
majority absorbed in the small intestine
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What are some of the issues with mineral absorption? Interactions? Competition?
a significant factor in the body’s ability to absorb minerals is bioavailability minerals can compete with each other for absorption thereby affecting each others bioavailability ex: excess of zinc can decrease the absorption and metabolism of the mineral copper this competition for absorption is of little concern when minerals are supplied by a varied diet; however, individual mineral supplements can create a serious imbalance choose mineral supplements that contain 10% less of the DV and use them under medical supervision
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What vitamins are synthesized in the body?
Vitamin A: can be synthesized from plant pigments → beta carotene to vitamin A Vitamin D: can be synthesized by skin in the presence of sunlight Niacin: can be synthesized from the amino acid tryptophan Vitamin K and Biotin: can be synthesized by gut bacteria to some extent
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Dietary supplement labels – what does USP mean on the label?
U.S. Pharmacopeia USP approved brands are tested to ensure that contaminants are not present in harmful amounts, that the ingredients listed on the label are actually in the supplements and will dissolve in the body, and that the supplements were made under safe sanitary conditions
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What is enrichment? Bread and cereals are enriched with what vitamins?
enrichment is used to add vitamins and minerals back into foods nearly all bread and cereal products made from milled grains are enriched with 4 B Vitamins thiamin, riboflavin, niacin, and folic acid → mineral iron
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What types of foods contain Vitamin C?
fruits and vegetables
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Why are refined grains less healthy than whole grains?
vitamin B-6 is lost during the refining of grains
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What are the functions of water in the body?
Temperature regulation Removal of waste products Component of body fluids Distribution of nutrients Lubricant Chemical reactions Acid base balance
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How does water regulate body temperature?
water has a high heat capacity of specific heat. this means that water resists temperature changes so its temperature rises slowly when it is heated sweat which is 99% water is the another way water helps maintain normal body temperature → perspiration cools the body
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What hormones participate in fluid conservation in the body? What role do they play?
Antidiuretic hormone (ADH) Secreted by pituitary gland when blood volume is down Tells kidneys to decrease water excretion which in turn increases blood volume Aldosterone and angiotensin Produced by adrenal glands Tells kidneys to conserve sodium and water
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Is thirst a good indicator of hydration status? Why or why not?
Controlled by your hypothalamus If thirsty, you are dehydrated Can lag behind in some situations, exercise, illness Infants and children → Need close monitoring, vomiting, diarrhea Hypothalamus sensitivity declines with age, increases dehydration risk in elderly the thirst mechanism does not always work well
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How much water (in cups) should athletes consume for each pound lost during exercise?
Consume 2-3 cups fluid/water each pound lost during exercise
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What are symptoms of dehydration/heat exhaustion/stroke?
mild to moderate dehydration dry mouth and skin fatigue and muscle weakness decreased urine output deep yellow (concentrated) urine, headache, and dizziness Extreme dehydration solute concentrations in the blood rise blood pressure decreases heart rate increases due to low blood volume kidney failure, seizures, delirium, coma, even death
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What is the daily adequate intake for water?
The adequate intake for total water intake per day is 15 cups (3.7 liters) for adult men and 11 cups (2.7 L) for adult women
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Can a person consume too much water?
Fatal water intoxication → hyponatremia Leads to seizures, comas, and death water accumulates in the blood and dilutes sodium in the serum causes cells to swell (brain cells swell and can cause death)
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What is the difference between intracellular and extracellular fluid?
body fluids are found in 2 body compartments Intracellular fluid: compartment → inside the cell ⅔ of body water is found in the intracellular fluid compartment Cations: Potassium and Magnesium Anions: phosphate and sulfate Extracellular fluid: compartment → outside of the cells cations: sodium and calcium anions: chloride and bicarbonate
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What are the functions of sodium?
3 major functions aids in water balance helps in the absorption of glucose and some amino acids in the small intestine required for normal muscle and nerve function main solute in extracellular fluid compartment so it regulates ECF and plasma volumes
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What are high sodium food sources?
most sodium in diets comes from processed foods mixed dishes (burgers, pizza, pasta, and sandwiches protein foods (cold cuts, cured meats, and processes meats various grains, vegetables, and snacks and sweets bottled sauces, condiments, spreads, and dips also contribute to sodium intake
Maintaining water balance Nerve impulse transmission Principal positively charged intracellular ion Increasing potassium intake can help lower blood pressure → 90% absorbed Low blood levels from chronic diarrhea, vomiting, laxative abuse is life threatening problem
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List three strong sources of dietary potassium?
Unprocessed foods Fruits, vegetables, milk, whole grains, dried beans, meats Major contributors in the diet include Milk, potatoes, beef, coffee, tomatoes, orange juice, bananas
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Who is at risk for potassium deficiency?
People with eating disorders, low food intake, vomiting, and laxative use make potassium depletion and hypokalemia a common and very serious problem those with alcoholism usually have poor diets and lack potassium athletes who exercise heavily may lose extra K in their sweat
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Who is at risk for high blood potassium levels?
those who have poor kidney function → potassium builds up in the blood and can cause an irregular heartbeat and even cardiac arrest