Type II Diabetes

DM epidemiology

healthcare costs

risk factors

-genetics

-age

-obesity

-physical inactivity

-environment

-medications

-shift work

age-adjusted prevalence of diabetes in US

who to screen for type II diabetes?

diagnostic criteria

diagnostic criteria for diabetes- A1C, FPG, OGTT

diagnostic pearls

genetics

pathophysiology

beta-cell physiology

mechanisms leading to dysfunction

beta-cell mass

insulin resistance

healthy adipose tissue v. hypertrophic adipose tissue

conditions that induce insulin resistance

gestational diabetes

-acanthosis nigricans

hepatic implications of DM

role of incretins in glucose homeostasis

role of the gut microbiome in T2DM

endocrinopathies and hyperglycemia

diseases of the exocrine pancreas

pancreatic cancer

prevention

take home points