Cardio Quiz 2

atorvastatin brand

Lipitor

atorvastatin class

statin

atorvastatin moa

inhibits HMG-CoA reductase, inhibiting cholesterol synthesis

atorvastatin use

hypercholesterolemia

atorvastatin dose

10-80 mg PO qD

atorvastatin contraindications

pregnancy, myopathy, active hepatic disease

atorvastatin bbw

none

simvastatin brand

Zocor

simvastatin class

statin

simvastatin moa

inhibits HMG-CoA reductase, inhibiting cholesterol synthesis

simvastatin use

hypercholesterolemia, hypertriglyceridemia, CV event prevention

simvastatin dose

5-40 mg PO qPM

simvastatin contraindications

pregnancy, myopathy, active hepatic disease

simvastatin bbw

none

hydrochlorothiazide brand

Esidrix, Microzide

hydrochlorothiazide class

thiazide diuretic

hydrochlorothiazide moa

inhibits DCT sodium and chloride resorption

hydrochlorothiazide use

hypertension, peripheral edema

hydrochlorothiazide dose

12.5-50 mg PO qD

hydrochlorothiazide contraindications

allergy to sulfonamides, anuria, CrCl

hydrochlorothiazide bbw

none

furosemide brand

Lasix

furosemide class

loop diuretic

furosemide moa

inhibits loop of Henle and PCT sodium and chloride resoprtion

furosemide use

edema

furosemide dose

40-120 mg PO divided qD or BID

furosemide contraindications

anuria, hepatic coma, electrolyte imbalance

furosemide bbw

in excess amounts can cause profound water and electrolyte depletion

rosuvastatin brand

Crestor, Ezallor Sprinkle

rosuvastatin class

statin

rosuvastatin moa

inhibits HMG-CoA reductase, inhibiting cholesterol synthesis

rosuvastatin use

hypercholesterolemia, hypertriglyceridemia, CV event prevention

rosuvastatin dose

5-40 mg PO qD

rosuvastatin contraindications

pregnancy, myopathy, active hepatic disease

rosuvastatin bbw

none

pravastatin brand

Pravachol

pravastatin class

statin

pravastatin moa

inhibits HMG-CoA reductase, inhibiting cholesterol synthesis

pravastatin use

hypercholesterolemia

pravastatin dose

10-80 mg PO qD

pravastatin contraindications

pregnancy, myopathy

pravastatin bbw

none

lisinopril & HCTZ brand

Prinzide, Zestoretic

lisinopril & HCTZ class

ACE inhibitor, thiazide diuretic

lisinopril & HCTZ moa

inhibits ACE, inhibits DCT sodium and chloride resorpiton

lisinopril & HCTZ use

hypertension

lisinopril & HCTZ dose

1-2 tab PO qD

lisinopril & HCTZ contraindications

pregnancy, allergy to sulfonamides, angioedema, anuria, CrCl

lisinopril & HCTZ bbw

not to be used during pregnancy

losartan & HCTZ brand

Hyzaar

losartan & HCTZ class

ARB, thiazide diuretic

losartan & HCTZ moa

selectively antagonizes angiotensin II receptors, inhibits DCT sodium and chloride resorption

losartan & HCTZ use

hypertension, stroke prevention

losartan & HCTZ dose

1 tab PO qD

losartan & HCTZ contraindications

pregnancy

losartan & HCTZ bbw

not to be used during pregnancy

spironolactone brand

Aldactone

spironolactone class

potassium sparing diuretic

spironolactone moa

Competes with aldosterone for receptor sites in the distal renal tubules, increasing sodium chloride and water excretion while conserving potassium and hydrogen ions

spironolactone use

hypertension, heart failure

spironolactone dose

25-100 mg PO divided qD or BID

spironolactone contraindications

hyperkalemia, pregnancy

spironolactone bbw

may increase tumor risk

fenofibrate brand

Tricor, Fenoglide, Lofibra, Triglide

fenofibrate class

fibrate

fenofibrate moa

inhibits triglyceride synthesis and stimulates catabolism of triglyceride rich lipoproteins

fenofibrate use

hypertriglyceridemia, hypercholesterolemia

fenofibrate dose

40-160 mg qD

fenofibrate contraindications

breastfeeding, active hepatic disease, gallbladder disease, biliary cirrhosis

fenofibrate bbw

none

lovastatin brand

Altoprev, Mevacor

lovastatin class

statin

lovastatin moa

inhibits HMG-CoA reductase, inhibiting cholesterol synthesis

lovastatin use

hypercholesterolemia, CV event prevention

lovastatin dose

10-80 mg PO qPM

lovastatin contraindications

pregnancy, myopathy, active hepatic disease

lovastatin bbw

none

hydralazine brand

Apresoline

hydralazine class

vasodilator

hydralazine moa

directly dilates peripheral blood vessels

hydralazine use

hypertension, heart failure

hydralazine dose

10-50 mg PO QID

hydralazine contraindications

coronary artery disease, mitral valvular rheumatic heart disease

hydralazine bbw

none

isosorbide mononitrate brand

Ismo, Monoket, Imdur

isosorbide mononitrate class

nitrate vasodilator

isosorbide mononitrate moa

stimulates cGMP production, resulting in vascular smooth muscle relaxation

isosorbide mononitrate use

angina prophylaxis

isosorbide mononitrate dose

20 mg BID or 30-120 mg ER qAM

isosorbide mononitrate contraindications

none

isosorbide mononitrate bbw

none

triamterene & HCTZ brand

Dyazide, Maxzide

triamterene & HCTZ class

thiazide diuretic combination (potassium sparing and non-sparing)

triamterene & HCTZ moa

inhibits DCT sodium and chloride resorption

triamterene & HCTZ use

hypertension, edema

triamterene & HCTZ dose

1-2 tab/cap PO qD

triamterene & HCTZ contraindications

allergy to sulfonamides, hyperkalemia, anuria, pregnancy, renal impairment

triamterene & HCTZ bbw

may cause hyperkalemia

ezetimibe brand

Zetia

ezetimibe class

cholesterol absorption inhibitor