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Globular protein shape
rounded or spherical
Fibrous Proteins shape
long and narrow extended line
Is Globular Protein water soluble
Yes
Is fibrous protein water soluble?
no
What are examples of globular proteins?
lysozyme, hemoglobin, insulin
What are examples of fibrous proteins?
collagen and keratin
Are Fibrous proteins more sensitive or less sensitive in heat and pH?
less sensitive
Are globular proteins more sensitive or less sensitive in heat and pH?
more sensitive
What is the role in Fibrous Proteins?
Structural (strength and support)
What is the role in globular Proteins?
Functional (catalysts and transport)
Enzymes
They catalyze/help speed up and regulate chemical reactions in the body
Examples of enzymes
Lactase and Amylase
Transport protein
embedded in cell membrane that help move molecules/ nutrients into/ out of cell
Examples of Transport proteins?
Proteins move sugar molecules, Proteins that move oxygen (hemoglobin)
Contractile Protein
Proteins that aid in cellular and molecular movement
Defense Protein
Protect the body from harm
examples of contractile protein
Motor proteins transporting molecules (actin and myosin)
examples of defense protein
antibodies
Signal Protein
Chemical messengers that help coordinate bodily activities
Examples of signal proteins
hormones (HGH, Insulin)
Receptor Protein
found in cell membrane receive and transmit signals to other cells; involved in cell-to-cell communication
Examples of receptor protein
Insulin receptor
Structural Protein
aid in structural support of cell, tissues, and organs in body
Storage Protein
Supply amino acids to developing embryos
Examples of storage protein
proteins found in eggs and seeds
Misfolded Proteins
A protein that was not folded properly when it was made thereby causing problems in the cell
examples of Misfolded Proteins
Alzheimer’s, Parkinson’s disease, ALS, and Mad Cow disease (caused by prions)
Denaturation
process in which a protein unravels, losing its specific shape and thus looses its specific function, which can be caused by excessive heat, pH changes, and salt conc change
Denaturation levels disrupted
Secondary, Tertiary, and Quaternary
Denaturation reversible or not reversible
Not reversible because you can never refold that amino acid chain back to the original 3D shape you originally have
Denaturation vs Hydrolysis (Hydrolysis)
Breaks down large molecules into small molecules with the use of a water molecule
What levels of structure is hydrolysis disrupted
Primary
Can the affects of hydrolysis be reversed?
Yes, you can reverse it by dehydration synthesis
What is dehydration synthesis?
you can take a water molecule of amino acids and start reforming a chain of amino acids
Carbohydrates (aka CHOs) have what?
molecular formula that is a multiple of CH2O (1:2:1 C:H:O)
number of hydroxyl groups (-OH) and a carbonyl group (C=O)
What is carbohydrates?
molecule group consisting of:
• single-monomer sugar (monosaccharides)
• two-monomer sugars (disaccharides)
• polymers (polysaccharides)
Monosaccharides
Simple sugars
• Mono = 1; saccharide = sugar
Sugar names end in “-ose” for monosaccharides
glucose, dextrose, and fructose
Enzymes that breakdown sugars end in “-ase” for monosaccharides
lactase, sucrase, maltase
What id monosaccharides the source of?
Quick energy and is also used in making other kinds of organic molecules
Disaccharides
generated by combining two monosaccharides using a dehydration reaction
Examples of disaccharides?
maltose, sucrose, and lactose
What is this?
Glucose C6H12O6
foods in maltose?
bread, beer, milkshake
Foods in sucrose?
pineapples and apricots
foods in lactose
milk and dairy products
What is maltose made of in monosaccharides?
glucose + glucose
What is sucrose made of in monosaccharides?
glucose + fructose
What is lactose made of in monosaccharides?
gluecose + galactose
What is this disaccharide?
maltose
What is this disaccharide?
sucrose
What is this disaccharide?
lactose
what is a Glycosidic bond?
Glucose monomers link together with a covalent bond and forms a disaccharide
Polysaccharide
composed of many monosaccharides linked together by dehydration reactions
polysaccharides function as?
long-term energy storage molecules and structural compounds
Common types of polysaccharides
Starch, Glycogen (liver), Cellulose, Chitin (seafood)
are almost all carbohydrates hydrophobic or hydrophilic?
hydrophilic due to the many hydroxyl groups attached to the sugar
Starch purpose
storage (long-term energy) and polysaccharide broken down (hydrolyzed) when glucose is needed for energy or building materials
Composition for starch?
glucose monomers
Structure of starch
single molecule with some branches
location of starch
plants only
examples of starch?
potatoes, grains/cereals/bread/pasta (wheat, corn, rice, oats), beans, chestnuts
What is this?
starch
what is Glycogen known as
animal starch
purpose of glycogen?
storage (long-term energy)
polysaccharide broken down (hydrolyzed) when glucose is needed for energy or building materials
composition of glycogen?
glucose monomers
structure of glycogen?
single molecule with many extensive branches
location of glycogen
animals only
examples of glycogen
In all animal cells and the highest in liver and muscle
what does glycogen do for us?
Humans/animals have enzymes that hydrolyze this into glucose...and then makes this for long-term cellular energy storage
What does starch do for us?
Humans/animals have enzymes that hydrolyze this to glucose...and then makes glycogen for long-term energy storage
cellulose known as?
dietary fiber
Cellulose purpose?
structural use (combine w/ polymers to produce support for plant)
storage (long-term energy)
broken down when glucose needed for energy or building material
cellulose composition
glucose monomers
cellulose structure
Polysaccharide chains linked together by H-bonds creating parallel stacks
cellulose location
plants only
examples of cellulose
plant cell walls
facts about cellulose
most abundant organic compound on Earth
humans and animals do NOT have enzymes that can hydrolyze cellulose to glucose – contributes to digestive health
termites, some bacteria (cow gut), fungi can break down cellulose
What is this?
Glycogen
What is this?
Starch
what is this?
cellulose
What is this?
glycerol
what is this?
fatty acid
monomers of lipids?
Glycerol and Fatty acid (FA)
Function of lipids?
Long-term energy storage
Component of plasma membrane
Metabolism and homeostasis
is nonpolar tail stable in water?
No
is polar head stable in water?
Yes
lipids
diverse group of molecules classified together due to one common trait: they are hydrophobic
why are lipids hydrophobic?
Due to nonpolar C-H bonds in hydrocarbon
common types of lipids?
Triglycerides (fats and oils), Phospholipids, Steroids, and Waxes
purpose of triglycerides?
Insulation and cushioning (fat in animals)
long-term energy storage
1 gram of fat stores more than 2x as much energy as 1 gram of polysaccharide
composition of triglycerides?
1 glycerol (3 carbons attached to –OH group)
3 fatty acids (carboxyl group and string of methyls)
Structure of triglycerides
fatty acids linked to glycerol molecule through dehydration reaction Two types of fatty acids:
Saturated fatty acids and Unsaturated fatty acids
location of triglycerides
plants and animals
examples of triglycerides
palm oil, olive oil, butter, lard
Unsaturated Fatty Acids
hydrocarbon chain contains 1+ double bonds, liquid at room temp – spoil quickly, and usually plant based
Saturated Fatty Acids
hydrocarbon chain contains all single bonds – carbons “saturated” w/ hydrogen, solid at room temp – long shelf life, and usually animal based
is this fatty acid saturated or unsaturated?
saturated
is this fatty acid saturated or unsaturated?
unsaturated
is this fatty acid saturated or unsaturated?
unsaturated