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Sequence Abiogenesis
abiotic synthesis of monomers
polymers/macromolecules
protocells
self-replication
4 requirements of a biogenesis
Little or no free oxygen
energy source
chemical building blocks
time
Sequence evolutionary events
Sequence endosymbiosis
Protcells properties
Self-Replication
Steps of formation of macromolecules
RNA
Sequence polarization
Properties of carbon molecules
Identify functional groups
Sequence scientific method
sequence levels of biology organization
compare atomic structure
compare ionic and covelant bonds
identify types of cells
common features of all cells
reason for cell size
nucleus function
sequence intracellular transport pathway and protein path through cell
sequence bulk transport
neuron plasticity
sensory memory
Short term memory
Long term memory
Encoding
Sequence learning process
Sequence memory formation
fluid mosaic model
Membrane components can move laterally within one layer of the membrane. Dependent on temperature, length of tails, bend in tails, amount of cholesterol.
hydrophilic
hydrophobic
van der waals forces
Develop because electron is in constant motion. Intermolecular (between molecules), can result bc of attraction between molecules (lizard sticking to a wall)
hydrogen bonds
Since water is polar, 1 molecule of water form bond with other molecules. Stick polar covenant molecules together, strong dipole dipole reaction, attraction between water molecules
polar bonds
Type of covenant bond. Less than 2 different electronegativity, electron shared unequally creating sides
non polar bonds
Same electronegativity, shame=re electron equally meaning no sides
atomic structure
hydrolysis
add a water and break bond (enzyme used is hydrolyses)
dehydration synthesis
removes water and joins (enzyme used are dehyrogenases)
glycosidic linkage
covenant bond between monosaccharides
disaccharides
2 monomer come together (still need dehydration synthesis to snap together)
polysaccharides
more than 2 monomers in a chain (sugar polymers)
synapse
junction where neuron sends chemical signal to another cell
amphipathic
glycerol+2 fatty acid=hydrophobic
Peptide Bonds
between amino acids (monomers), dehydration synthesis reaction
Tertiary Structure
Within single polypeptide. R-groups interacts, folds into 3d structure
denaturation
loss of proteins 3rd or 4th structure
organic polymers
exhibit attributes of living cells: 1. osmosis 2. homeostasis 3. divide (cannot pass on genes)
serial endosymbiosis
endosymbiosis that happens more than once
eukarya-
arise from archaea and bacteria
aerobic bacteria-
uses o2 for cell respiration. the domain of archaea later
cell theory
all life is made of cells 2. all cells have 4 common features 3. all cells have a common evolutionary ancestor
mitosis
nucleoid
found
chromatin
DNA+Proteins
surface tension
How hard it is to break the surface of a liquid
adhesion
Water molecules stick to other polar things
cohesion
Water molecules stick to each other
electronegativity
Tendency of an atom to attract an electron
endoplasmic reticulum
Continuous with nuclear envelope and has smooth and rough portions
Golgi apparatus
Modifies ER products, sorts and packages, manufactures some macromolecules, ships products using transport vesicles. (Receiving and shipping sides)
Ribosomes
Synthesize primary polypeptides. All cells have.
Endomembrane system
Phospholipid belayers, closed compartments, continuous, regulates protein folding/movement and metabolic function
Plasma Membrane
All cells have, encloses cell contents, permeable
Nuclear Envelope
Encloses DNA, instructions for a protein (mRNA) to leave through nuclear pores.
Smooth ER
No ribosomes, not processing. Synthesizes lipids, metabolizes polysaccharides (breaks down glycogen), detoxifies drugs/poisons, stores calcium ions
Rough ER
Surface has ribosomes. Proteins folded and modified, secrete glycoproteins (Protein bounded carbs), distributes transport vesicle, cell membrane factory
Endosymbiont theory
Eukarya arise from archea
Ionic bonds
Greater than 2 electronegativity, intramolecular, one atom steals electron from the other, bond formed by attraction between anion (neg) and cation (pos), bonds dissociate in water
4 things all cells must have
Membranes, own dna, undergo binar fission, own ribosomes
Membrane protein functions
Transport, enzymes, signal transduction
Sequence synthesis of macromolecules
Polymers form, monomer polymerize, ion bond monomers
How do photocells form
Lipids form vesicles creating organic polymers
Passive transport
Don’t use metabolic E (ATP) and move with gradient. Spontaneous, results in dynamic equilibrium. Includes simple diffusion, osmosis, and facilitated diffusion. Small gasses, smaller non polar molecules, and small polar uncharged molecules use.
Active transport
Does use metabolic E (ATP) and moves against the gradient. Transports large polar molecules. Facilitated by proteins (carriers or pumps) or bulk transport.
Diffusion
Tendency for molecules of a substance to fill and available space
Osmosis
Diffusion of water across selectively permeable membrane. Water diffuses from higher to lower
Solvent
Substance capable of dissolving other substances
Solute
A dissolved substance
Osmosis tonicity
Ability of a solution to cause a cell to lose/gain water
Isotonic solution
Solute inside the cell = to solute inside the cell
Hypertonic solution
Solute (outside cell)> solute (inside cell)
Hypotonic solute
Solute (outside cell)< solute (inside cell)
Sequence facilitated diffusion
Larger molecules/ions transport proteins ——— integral proteins channel proteins —- ion channel —- carrier protein —-specific to transport
Pumps/carriers
Integral membrane protein that changes shape.
Formation of vesicles
Active and always requires ATP. Does not pass through plasma membrane
Bulk transport
Large number of molecules transported at once, no carrier mediated.
Exocytosis
Waste proteins and secretory products taken out. Vesicles fuses with plasma membrane which releases contents. Vesicles fusing with membrane is growth of plasma membrane
Endocytosis
Materials taken into the cell by forming vesicles derived from plasma membrane
Phagocytosis
Type of endocytosis. Cellular eating. Cell engulfs large particle, non specific
Pinocytosis
Cellular drinking. Ingestion of fluid and dissolved material, non specific
Receptor mediated
Specific, receptor proteins in plasma membrane bind specific macromolecules outside of the cell leading to the formation of coated pits leading to it folding inward creating vesicles. This is the main mechanism for the uptake of macromolecules.
ATP
Cells use ATP to carry energy. It is a spring loaded bond. Take ATP and take off a phosphate, still have 2, the other is now an inorganic phosphate and the phosphate coming off is energy. To make ATP add a phosphate
Coupled reactions
Pair emergencies reaction (provides E) with an endergonic reaction (requires E)
Phosphorylation
How ATP drives endergonic reactions. Phosphate group transferred to molecule which now has a new shape and thus a new function
Activation E
Initial energy needed to start a reaction
Enzymes
They speed up reactions by lowering energy barriers
Substrate
Reactant that an enzyme acts upon. Change of shape facilities breaking of bond.
Active site
Cleft or groove for substrate
Factor affecting enzyme activity
Temperature and pH. Enzyme has an optimal temperature
Denaturation
High temp= short exposure leading to denature enzyme. Low temp=enzymatic reaction leads to it slowing or having no impact.