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bones
Organs along with the associated cartilages form the skeletal system
Made up of at least 2 types of tissue
Functions of Bones
Support
support the framework of the body
support viscera (ventral body cavity)
provide attachment points for tendons
Protection
Protect internal organs from injury
Assistance in Movement
skeletal muscles attach to the bones by tendon
when skeletal muscles contract, they pull on the bones → produce movement
Mineral Storage and Release
Includes calcium and phosphate
Site of Blood Cell Formation = Hemopoiesis = Hematopoiesis
Production of blood cells in red bone marrow
Triglycerides Storage
Stored in the yellow bone marrow (a type of lipids/fats)
long bones
characteristics
has a shaft and 2 distinct ends
examples:
humerus
femur
tibia
short bones
characteristics
Equal in length, width and height
examples:
Carpals, tarsal
flat bones
characteristics
Thin, flat, curved → form a cavity
examples:
Sternum, front bone
irregular bones
characteristics
Not a long, short, or flat bone
examples:
Vertebra, sphenoid
sesamoid bones
characteristics
Small bones embedded in tendon
examples:
Patella (knee cap)
Diaphysis
Description = the long cylindrical, main portion of the bone
The shaft or the body of the bone
Epiphysis
end of the bone: proximal, distal
Metaphyses
The region between diaphysis and epiphysis
Includes the epiphyseal plate → aka growth plate
Epiphyseal Plate= replaced by epiphyseal line when the bone stops lengthening
Articular Cartilage
Hyaline cartilage covering epiphysis to form joints
covers end of opposing bones
Function= reduce friction and absorb shock
Periosteum
A connective tissue sheath
Composition (of 2 layers)= outer fibrous layer, inner osteogenic layer
Sharpey’s fibers = perforating fibers = attach the periosteum to the underlying bone
Medullary Cavity= Marrow Cavity
Description = long, cylindrical space within the diaphysis
Composition = contain yellow bone marrow and blood vessels
Function = reduce dene boney material
Long bone design maximize strength and minimize weight → run faster, stronger bones
Endosteum
Thin membrane that lines the medullary cavity
Blood Vessels
Structure of Other Types of Bones – outer plates of compact bone covering an inner core of spongy bone
Bone Surface Markings = Osseous Markings
structural features that adapt to specific function
2 major types: (1) depressions and openings, (2) processes
Examples include= fissure, foramen, fossa, sulcus, meatus, and process
Histology of Bone Tissue
Bone = osseous tissue contains a matrix surrounding widely separated cells.
The matrix contains mineral salts (hydroxyapatite and calcium) deposited in a framework of collagen fibers.
Collagen fibers give bones flexibility and tensile strength.
Calcification of bone gives bone hardness.
Osteoblasts
Description = bone building cells
Function = produce tissue matrix
Location = not completely surrounded by matrix
Osteocytes
Description = mature bone cells
Function = maintain osseous tissue
Location = completely surrounded by matrix → found inside a lacuna
Osteoclasts
Description = made from the fusion of many monocytes
Function = break down bone matrix → called bone resorption
Compact = Cortical = Dense Bone Tissue
dense
has smaller spaces than spongy bone
Microscopic Structure of Compact Bone
composed of osteons = Haversian system – repeated structural units of columns of bone
central or Haversian canal – contains blood vessels, lymphatic vessels, and nerves
circumferential lamellae
arranged around entire outer or inner circumference of the shaft of the long bone
Canaliculi
slender, finger-like processes of osteocytes inside
small channels radiating in all directions from lacunae filled with interstitial fluid
perforating; Volkmann’s canal
canals that transverse through the periosteum
Spongy = Trabecular = Cancellous Bone Tissue
less dense than compact bone
have larger spaces than compact bone
contains bone marrow
Bone Growth and Development
bone formation involves ossification which begins around 6th week of embryonic life and continues throughout adulthood
ossification occurs via 2 processes in which preexisting connective tissue is replaced by bone tissue
Intramembranous Ossification
Occurs within fibrous connective membranes
Involves 4 steps:
ossification center development
calcification
trabecular formation
periosteal formation
Endochondral Ossification
Occurs within a hyaline cartilage model
Cartilage grows by interstitial and appositional growth
Primary Ossification Center
Forms in the diaphysis before birth
The medullary cavity forms
Bone grows in diameter by the osteogenic periosteum via appositional growth (a process in which osteoblasts from the periosteum add new bone to the outer surface)
Forms the articular cartilage and epiphyseal plate
Secondary Ossification Center
Forms in the epiphyses after birth
Strengthens the epiphyses for walking
The growth end of the long bone retain a strip of cartilage called the epiphyseal disc to allow the bone to grow in length
Bone Remodeling
New bone tissue is continuously deposited and resorbed in response to hormonal and mechanical stimuli
Osteoclasts break down bone tissue by secreting digestive enzymes and acids onto bone surfaces. This process releases calcium and phosphate into the blood
Osteoid is secreted by osteoblasts at areas of bone deposits. Calcium salt is then deposited in the osteoid (Bone Deposition)
Compressive forces and growth acting on the skeleton help maintain bone strength because bones thicken at sites of stress
Aging
1. demineralization of bone matrix (loss of Ca2+ is a major factor in development of osteoporosis)
2. decrease rate of protein (mainly collagen) synthesis results in loss of tensile strength, making bones more brittle and susceptible to fractures
Osteosarcoma
most common form of bone cancer primarily in teenagers during their growth spurt
Osteomyelitis
an infection of bone characterized by high fever, sweating, chills, pain, and nausea. It is usually caused by Staphylococcus aureus
Osteopenia
reduced bone mass due to various causes
Osteoporosis
bone resorption outpaces bone deposition
occurs often in women after menopause
in the elderly, the neck of the femur has low bone mass and breaks; then the person falls
hip fractures!
Ostealgia
pain in a bone
Boney Spur
an abnormal projection on a bone due to bone overgrowth
common in aging bones
concentric lamellae
circular plates of mineralized extracellular matrix of increasing diameter
interstitial lamellae
fragments of older osteons partially destroyed during bone rebuilding or growth
lacunae
small spaces between concentric lamellae containing osteocytes
overview of skeleton
consists of bones, joints, cartilage, and ligaments
composed of 206-208 named bones in the adult skeleton grouped into 2 major divisions
axial skeleton
appendicular skeleton
axial skeleton
80-82 bones
located around the longitudinal axis of the body
includes the skull, vertebral column, ribcage, auditory ossicles & hyoid
skull
composed of 22 bones
cranial bones= 8 cranial bones to form cranial cavity to protect the brain
facial bones= 14 facial bones to form the face
ribcage
sternum, costae, thoracic vert
vertebral column
cervical, thoracic & lumbar vertebrae, sacrum, coccyx
strong, flexible rod with functions; protects the spinal cord (nervous tissue)
supports the head
auditory ossicles
malleus, incus, stapes
appendicular skeleton
126 bones
includes the pectoral girdle, brachium, anterbrachium, manus
includes the pelvic girdle, femoral region, leg, pedus
cranial bones
inner surfaces= attach to membranes
outer surface= provides attachments for muscles
formation= form cavities for sense organs: hearing, equilibrium
frontal bone
1 bone
pariteal bone
2 bones
occipital bone
1 bone
temporal bone
2 bones
sphenoid bone
1 bone
ethmoid bone
1 bone
facial bones
14 bones
function= provides support, protect entrance of digestive and respiratory tract
formation= forms the cavity for sense organs for vision, smell, and taste
provides attachment for facial bones
nasal septum
formed by the vomer, septal cartilage, perpendicular plate of ethmoid bone
divides the nasal cavity into right and left compartments
orbital cavity
formed by frontal, sphenoid, zygomatic, maxillary, palatine, lacrimal, and ethmoid bones
houses the eyeballs, eye muscles, and lacrimal glands
sutures
immovable joints between skull bones
point of attachment for 2 cranial bones
appears irregular and saw-tooth
coronal suture
frontal & parietal bones
sagittal suture
2 parietal bones
squamous suture
parietal & temporal bones
lambdoid suture
parietal and occipital bones
paranasal sinuses
paired cavities located in certain skull bones
lined w/ mucosa that are continuous w/ lining of the nasal cavity
function= produce mucus & serve as resonating chambers of sound
located in maxillary, frontal, sphenoid, and ethmoid bones
fontanel
fibrous connective tissue membrane= filled spaces between cranial bones
point of attachment for 3 cranial bones
function= fetus modify skull through birth & permits rapid growth of the brain during infancy
includes= anterior fontanel, posterior fontanel, sphenoid fontanel, mastoid fontanel
hyoid bones
“U” shaped bone
location= in the superior neck, inferior to the mandible
does not articular with any other bone
function= supports the lengua
attachment site= for lingual, cervical, pharyngeal muscles
cervical vertebrae
named C1-C7
C1= atlas
C2= axis
thoracic vertebrae
named T1-T12
attached to costae= ribs
lumbar vertebrae
named L1-L5
sacrum
fusion of 5 sacral vertebrae
coccyx
fusion of 3-5 coccygeal vertebrae
primary curvature (concave)
retains original curvature of embryonic vertebral column
thoracic curve
sacral curve
secondary curvature (convex)
begins to form later, several months after birth
may be progressively lost in old age
cervical curve= obtained when baby lifts up its head by 2 months
lumbar curve obtained when baby sits up between 5-7 months
intervertebral discs
located between neighboring vertebrae frm C2 down to sacrum
composed of fibrocartilage
functions:
form strong joints
permits various movement of the spine
absorb vertical shock
thoracic cage
sternum, thoracic vertebrae, costae
function= protect the organs of the thoracic cavity (lungs, heart, trachea, esophagus, aorta)
supports the pectoral girdle and upper extremities
sternum
flat bone composed of 3 major regions:
manubrium
body
xiphoid process
includes sternal angle and xiphosternal angle or joint
ribs= costae
12 pairs of ribs
all ribs are attached posteriorly to the thoracic vertebrae
anteriorly, the superior 7 pairs of ribs attach directly to the sternum via costal cartilages and are called true ribs= vertebrosternal ribs
the inferior 5 ribs called false ribs are attached to the sternum indirectly or not at all
pairs 8-10, are also called vertebrochondral ribs= vertebral ribs
the last 2 of the 5 inferior ribs (ribs 11 & 12) aka floating ribs because they have not anterior attachments
intercostal spaces are spaces between neighboring ribs
orthopedists= orthopedic surgeon
a physician who specializes in restoring lost function or repairing damages to bones and joints
chiropractic
holistic health-care discipline that focuses on nerves, muscles, and bones
chiropractor
a doctor who practices chiropractic
cleft plate
the right and left halves of the palate fail to join medially
whiplash injury
an injury to the neck region caused by rapid sequence of hyperextension (backward tilting) followed by hyperflexion (forward tilting) of the neck
scoliosis
abnormal lateral curvature of the thoracic region of the spine (S shaped spine)
kyphosis
hunchback
exaggerated thoracic curvature
lordosis
“swayback” or “hollow back”
accentuated lumbar curvature
pectoral girdle= shoulder girdle
attached the bones of the free upper extremities to the axial skeleton
includes 3 bones= (1) clavicle, (2) scapula, (3) humerus
fractures of the clavicles
results from a blow to the superior part of the anterior thorax
upper limb= upper extremity
composition= includes arm, forearm, and hand
hand
composed of carpals= 8 carpal bones in the wrist
5 metacarpal bones
found in the palm of the hand; I, II, III, IV
phalanges
14 bones, located in the digits
proximal
medial
distal
boxer’s fracture
fracture of the metacarpal V, usually near the head of the bone
carpal tunnel syndrome
compression of the median nerve due to the repeated flexing of the fingers an wrists
seen commonly in people who use computers all day long
pelvic girdle= hip girdle
connects the bone of the free lower extremities to the axial skeleton
composed of the paired hip bones called os coxae or pelvic bone
each os coxae is composed of 3 fused bones:
ilium
ischium
pubis
pubic bones united anteriorly by the pubic symphysis composed of fibrocartilage
sacrum articulates with the os coxae posteriorly at the sacroiliac joint
the deep, basin-like structure formed by the os coxae, sacrum, and coccyx= bony pelvis
false pelvis
superior to the pelvic brim
true pelvis
inferior to the pelvic brim
female pelvis
adapted for childbearing
lower limb= lower extremity
includes the thigh, leg, and foot