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physiological anemia
blood volume increases more then the actual contents → hemodilution
anemia parameters: < 11 (1/3 trimester) or 10.5 (2 trimester), < 9 severe anemia
Rh isoimmunization
Rh- mother is tested at 28 weeks to see if she has antibodies against Rh+ to protect fetal RBCs from hemolysis.
+: already made Rh antibodies, Rhogam shot is no longer affective,
-: no Rh antibodies, no sensitization yet, given anti-D igG antibodies then and 72 hours after birth
complications of untreated STI in pregnancy: chlamydia
PROM, preterm labor, postpartum endometritis, neonatal conjunctivitis/pneumonia
complications of untreated STI in pregnancy: gonorrhea
PROM, preterm birth, neonatal blindness, neonatal sepsis, chorioamnionitis, PP sepsis and endometritis
complications of untreated STI in pregnancy: syphilis
stillbirth, congenital syphilis
complications of untreated STI in pregnancy: HPV
warts can obstruct birth canal → c-section
complications of untreated STI in pregnancy: trichomoniasis and BV
PROM, preterm birth, PID
complications of untreated STI in pregnancy: candidiasis
discomfort, neonatal oral thrush
complications of untreated STI in pregnancy: GBS
risk for neonatal sepsis, meningitis, pneumonia
complications of untreated STI in pregnancy: covid
preterm birth, stillbirth, preeclampsia, hemorrhage, HTN, clotting disorders
complications of untreated STI in pregnancy: CMV
fetal growth restriction, hearing loss, neurologic issues
complications of untreated STI in pregnancy: HSV
neonatal HSV
complications of untreated STI in pregnancy: HIV
c-section at 38 weeks if viral load > 1000 copies/mLH
HPV
Most common STI
spread via skin to skin sexual contact
can be asymptomatic
risks: cervical vulvar vaginal anal penile oropharyngeal cancer (type 16 and 18) genital warts (type 6 and 11)
HPV: treatment
screening: pap smears for ages 21-65
treatment: imiquimod cream for non-pregnant pt, BCA or TCA applied by HCP for pregnant woman
vaccine: HPV recommended for ages 11-12, catchup to 26
GIFT
gamete intrafallopian tube
eggs + sperm mixed and placed directly into fallopian tube
fertilization occurs in body → one patent tube required
female causes of infertility: ovulation disorders/anovulation
disruption of hypothalamic pituitary ovarian axis (hormone feedback system)
risk factors: aging, obesity, PCOS, hyperprolactinemia, strenuous exercise, early menopause, eating disorders, cancer treatment, smoking, depression, environmental toxins, high caffeine, alcohol
female causes of infertility: tubal occulusions
scarring, infections (PID), prior sterilizations, tumors
female causes of infertility: endometriosis
endometrial tissue implants outside uterus
inflammation → adhesions/scarring → egg quality decreases, interferes with egg release, sperm transport, implantation
male causes of infertility: decrease sperm production
undescended testes, hypospadias, varicocele, low testosterone, prior vasectomy, testicular cancer, pituitary tumors, mumps
types of decreased sperm production (2)
azoospermia: no sperm
oligospermia: few sperm
infertility diagnostic procedure: female (7)
pelvic exam: structural abnormalities
hormone analysis: hypothalamic-pituitary-ovarian axis
postcoital test: sperm motility and mucus compatibility
US: cysts and uterine fibroids
hysterosalpingography: contrast dye for tubal patency
hysteroscopy: view uterus for fibroids/adhesions
laparoscopy: check for endometriosis, adhesions, tubal blockages
infertility diagnostic procedure: male (3)
semen analysis: sperm count, morphology/quality, motility - cheap but must be done within first hour of ejaculation
US: scrotal (varicocele) and transrectal (ejaculatory ducts, seminal vesicles, vas deferens)
hormone levels: testosterone
nursing interventions
encourage communication and recognize infertility as major life stressor
assist the couple with education and options (ART and genetic counseling)
monitor for adverse effects of infertility medications
referrals to grief and infertility support groups
medications for STIs: chlamydia
pregnant: doxycycline
non-pregnant: azithromycin
infants: erythromycin eye ointment
medications for STIs: gonorrhea
ceftriaxone IM, azithromycin PO
infants: erythomycin ointment
medications for STIs: syphilis
penicillin G or Bicillin IM
1 dose, 3 doeses if unkown duration
medications for STIs: trichomoniasis
mentronidazole (avoid first semester), tinidazole
medications for STIs: BV
metronidazole or clindamycin, given probiotic for prevention
medications for STIs: candidiasis
topical antifungals (clotrimazole, OTC)
medications for STIs: GBS
intrapartum IV penicillin G or ampicillin
medications for STIs: toxoplasmosis
sulfonamides, pyrimethamine +msulfadiazine
medications for STIs: HSV
acyclovir/valacyclovir, suppressive therapy later in pregnancy
types of signs of pregnancy (3)
presumptive: subjective, felt by patient, not proff
probable: objective, observed by HCP, suggestive but not definite
positive: proof of pregnancy
Presumptive signs of pregnancy
Amenorrhea
Fatigue
Nausea/vomiting
Urinary frequency
Breast changes: dark areoles, enlarged Montgomery glands
quickening: fluttering fetal movements 16-20 weeks
uterine enlargement
probable signs of pregnancy
abdominal enlargement
hegar’s: softening of lower uterus at 6 weeks
chadwick’s: blue cervix/vaginal mucosa at 6-8 weeks
goodell’s: softening of cervical tip at 6 weeks
ballottement: fetus rebounds when tapped at 16-18 weeks
braxton-hicks contractions
positive pregnancy test
fetal outline palpable
positive signs of pregnancy
fetal heart tones
visualization of fetus on US
fetal movement palpated by HCPf
fundal height
after 20 weeks, fundal height in cm = gestational age ± 2 weeks
can be due to previous pregnancy, hydration, retroverted uterus etc
fundal height landmarks
12-14 weeks: above symphysis pubis
20-22 weeks: umbilicus
38-40 weeks: fundal height decreases due to lightening
Pica
non food cravings such as ice clay dirt and laundry detergent
nursing consideration: see if mother is anemic or has poor weight gain
diaphragm
silicone dome placed over cervix with spermicide
fitted by HCP, replaced q2 years or after weight change/pregnancy
insert <6 hours before sex, leave >6 hours after, max 24 hours
reapply spermicide each act
does not protect against STIs
contraindicated for patients with hx of TSS or UTIs
emergency contraception options (3)
levonorgestrel (plan b): within 72 hours, OTC, all ages, one dose
ulipristal (ella): prescription, up to 5 dyas
copper IUD: most effective, up to 5 days
emergency contraception education
not BC or termination → prevents implantation by stopping ovulation and sperm transport
earlier you take it, more effective
side effects: nausea, heavier bleeding, abdominal pain, HA, fatigue
provide counseling on regular contraception s
supine hypertension syndrome/vena cava syndrome
happens after 20 weeks of pregnancy
enlarged uterus compresses vena cava when mom lies on her back → occludes the inferior vena cava → venous return and preload drop → maternal hypotension and fetal hypoxia or distress c
clinical manifestations of supine hypotension
dizziness
lightheadness
pallor
clammy cool skin
nursing considerations: supine hypotension syndrome
teach pregnant patients to avoid lying flat on their back
position in left lateral recumbent or semi-sitting position
Naegele’s rule
calculation to determine EDB
first day of LMP - 3 months +.7 days
warning signs: first trimester
Dysuria
severe vomiting
diarrhea
fever or chills
abdominal cramping
vaginal bleeding
warning signs: second and third trimester
gush of fluid from vagina → rupture of amniotic fluid
vaginal bleeding → placenta problems
abdominal pain → PROM, ectopic pregnancy, placenta abruption
changes in fetal activity → fetal distress
persistent vomiting → hyperemesis gravidarum
severe headaches → gestational HTN
elevated temp → infection
dysuria → UTI
blurred vision → gestational HTN
edema face and hands → gestational HTN
epigastric pain → gestational HTN
flushed dry skin, fruity breath, headache, rapid breathing, increased thirst and urinations _> hyperglycemia
clammy pale skin, weakness, tremors, irritability, lightheadness → hypoglycemia
terbutaline side effects
uterine smooth muscle relaxation
maternal tachycardia
GBS testing
bacterial infection passed to fetus during L&D, colonizes in the vagina/rectum/uretha of pregnant women
35-38 weeks: vaginal and rectal cultures
+: overgrowth of bacteria, given intrapartum IV penicillin G or ampicllin
risk of neonatal sepsis, meningitis, pneumonia
Leopold’s maneuver
superior surface of fundus: determine what part of fetus is in fundus (head or buttocks)
both sides of uterus: determine the fetal back direction (longitudinal vs transverse)
palpate pubic symphysis: identify presenting part/in inlet (head or buttocks/vertex or breech)
palpate both sides of lower uterus: fetal attitude (flexed vs extended head)
contradictions for hormonal conceptions
Hx of thromboembolic disorders (DVT, stroke, MI)
estrogen dependent cancer (breast, endometrial)
unexplained vaginal bleeding
severe liver disease
smokers > 35 years old
uncontrolled HN
migraines
DM
ACHES: combined oral contraceptions
Abdominal pain
Chest pain/SOB
Headache/vision changes
Eye problems
Severe leg pain
fetal kick count
normal: 10 movements in 2 hours
report if none in 12 hours or <3/hour
pt ed: mother should eat or drink, lie on life side
cardiovascular changes during pregnancy: blood volume
40-50% increase to compensate for blood loss during birth and postpartum
cardiovascular changes during pregnancy: cardiac output
30-50% increase (increased SV and HR to meet tissue oxygen demand)
cardiovascular changes during pregnancy: HR
increase of 10-15 bpm beginning at 5 weeks and peaks at 32 weeks
hormonal and volume effects
cardiovascular changes during pregnancy: BP
same or slight decrease
caused by vasodilation due to progesterone increase
cardiovascular changes during pregnancy: structural
heart enlarges and shifts upward/laterally due to uterus displacing diaphragm
FHR baselines
110-160 bpm
accelerations: > 15 bpm for >15 seconds
moderate variability: 6-25 bpm
FHR assessment dates
6-7 weeks/<12 weeks: transvaginal US
10-12+ weeks: doppler device
continuos monitoring: external (doppler US transducer) or internal (fetal scalp electrode)
hormones affecting pregnancy: hCG
keeps corpus luteum alive in early pregnancy by making progesterone until placenta takes over
hormones affecting pregnancy: progesterone
relaxes smooth muscle, less uterine contractility, maintains endometrium
hormones affecting pregnancy: estrogen
uterine growth, breast changes, fat deposition in subq tissues
hormones affecting pregnancy: hPL
breast development, more fatty acids alters maternal metabolism
hormones affecting pregnancy: prostaglandins
cervical ripening, uterine contractions
hormones affecting pregnancy: pituitary gland
enlarges in pregnancy
prolactin increases → prepares breasts for milk production after birth
hormones affecting pregnancy: pancreas
insulin needs to increase during 3rd trimester for fetus
reason for screening at 24-28 weeks with 1 hour GTT
external abdominal US
safe noninvasive painless procedure
gel applied on abdomen → enhances sound wave trnasmission
best used after first trimester due to larger uterus
full bladder required
transvaginal US
invasive: vaginal probe inserted
more accurate evaluation → clear pelvic organs and fetal structures
pt ed: feel pressure during probe movement
transvaginal US use
1st trimester: detect ectopic pregnancy, monitor developing embryo, identify abnormalities, establish gestational age
3rd trimester: evaluate preterm labor
also used for obese patients
doppler blood flow US
noninvasive external US → measures maternal-fetal blood flow in vessels
common vessels assessed: fetal umbilical cord, middle cerebral and maternal uterine arteries
doppler blood flow US uses
fetal IUGR
poor placental perfusions
high-risk pregnancies: HTN, DM, multiple gestations, preterm labor
lightening
when baby drops lower in pelvis in preparation for birth
reason why fundus goes down after 38 weeks
advanced maternal age (>35)
risk for (even with good prenatal care):
infertility, miscarriage, chromosomal abnormalities, HTN, gestational DM
external fetal monitoring (2)
US transducer: FHR
toco transducer: contractions
internal fetal monitoring (2)
scalp electrode: FHR baseline variability, dysrhythmias, accels/decels
intrauterine pressure catheter (IUPC): contractions and resting tone
Intermittent auscultation and uterine contraction palpation uses
fetal well being: used to determine frequency, intensity, duration, resting tone
during contractions: compresses uteroplacental arteries → fetal circulation and oxygenation decreases → early decels if everything is okay, late if not
guidelines for IA or continuous EFM
latent phase: every 30-60 minutes
active phase (> 6 cm): every 15-30 minutes
second stage (active pushing): every 5-15 minutes pr
prenatal care goals (4)
promote health ed
monitor fetal growth/development and identify abdnormalities
identify diagnose and treat preexisting maternal disorders
support maternal self-care and parenting (including family/partner)
first trimester teaching
physical/psychological changes, exercise, nutrition, safe sex, dental care, alcohol, tobacco, fetal growth and development, prenatal exercise, expected lab findingsfri
first semester common discomforts
n/v
breast tenderness
urinary frequency
fatigue
second trimester pt ed
breastfeeding benefits, sex, posture, seat belt safety, fetal movement, rest, travel safety
complications: preterm labor, gestational HTN and DM
common discomforts: heartburn, constipation, hemorrhoids, back pain, Braxton Hicks, varicose veins, lower extremity edema, gingivitis, supine hypotension, UTI
third trimester pt ed
childbirth classes, coping, pain management, newborn care, use of TENS, CAM modalities
common discomforts: heartburn, constipation, hemorrhoids, back pain, Braxton Hicks, varicose veins, lower extremity edema, gingivitis, supine hypotension, UTI, leg cramps
MSAFP: maternal serum alpha-fetoprotein
15-22 weeks
noninvasive and no risk to baby
measures AFP, a protein normally produced in fetal liver and crosses placenta into mother’s blood
if abnormal, quad marker screenings, genetic counseling, US, amniocentesis
low = Down’s syndrome, high = neural tube defect or multifetal pregnancy
initial prenatal visit interview
reason for seeking care
current pregnancy EDM
childbearing and female reproductive hx
health hx
nutritional hx
medication and herbal preparation use
family hx
social experiential occupational hx
mental health screening
intimate partner violence risk
ROS
initial prenatal visit: physical exam
prep: emply bladder before pelvic exam
baseline data: vitals, pelvic exam
approach: gentle, unhurried, provide info
bp monitoring
initial lab testing
urine, cervical, blood samples
CBC
blood type and Rh
rubella abx
hepatitis b and c screen
pap smear
STI testing
vaginal/cervical culture
urinalysis/renal function
TORCH screen
venereal disease research lab (VDRL)
HIV testing
TB testing
genetic testing: sickle cell disease, cystic fibrosis, Tay-Sachs
1 hour glucose test
screens for gestational DM between 24-28 weeks
Mother drinks 50 g of glucose, blood is drawn exactly 1 hour later
normal": <130 mg/dL
if abnormal, do the 3 hour glucose test
3 hour glucose test
Mother fasts overnight and drinks 100 g of glucose
blood levels measured at: fasting, 1 hour, 2 hour, 3 hour
diagnosed with DM if 2+ abnormal values
teen pregnancy
less likely to receive adequate prenatal care
risks: anemia, preeclampsia, preterm birth, low birth weight, social/financial challenges
pt ed: stress importance of early/continuous care, provide ed/suppoort
cervical changes in pregnancy
Goodell’s sign: softening of cervix tip
Chadwick’s sign: bluish purple discoloration of cervix due to increased blood flow
friability: cervical tissue becomes delicate, may bleed slightly after examination
operculum/mucus plug: rich in immunoglobins, protects uterine cavity from bacterial invasion
integumentary changes in pregnancy
hyperpigmentation: more melanotropin from anterior pituitary
melasma: brown facial patches, mask of pregnancy
linea nigra: dark line from pubis to fundus
striae gravidarum
angiomas (spider/cherry): small arteriolar proliferations on neck, face, arms
palmar erythema: pink/red patches on palms from elevated estrogen
pruritus gravidarum: mild abdominal itching
hair and nail growth: accelerated
BPP test
comprehensive assessment that combines NST with fetal US
purpose: visualize physiological characteristics of fetus and measure fetus well-being bt measuring 5 specific variables
5 variables assessed in BPP
FHR
fetal breathing movement: one episode of breathing movement > 30 seconds within 30 mins
gross body movements: 3+ body or limb extensions with return to flexion within 30 mins
fetal tone: 1 episode of extension with return to flexion
qualitative amniotic fluid volume: at least 1 pocket of fluid that measures at least 2 cm
BPP score
each variable: 2 (normal) or 0 (abnormal)
8-10: normal
4-6: abnormal, suspected fetal hypoxia