facts TO KNOW for final

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plural fluid

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terms and concepts that i starred in my notes bc prof told us we need to know

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plural fluid

clear fluid that minimizes friction between the tissues and provides surface tension in pleural cavity

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surfactant

chemical substance secreted by lungs to facilitate surface tension (prevents collapse of alveoli)

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tidal volume (TV)

amount of air moving in and out of the lungs during normal breathing

  • average = 500 ml

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inspiration reserve volume (IRV)

amount of air that can be inhaled after normal inspiration

  • average = 3000 ml

  • calculated IRV = IC - TV

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expiratory reserve volume (ERV)

amount of air that can be exhaled after normal expiration

  • average - 1100 ml

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inspiratory capacity (IC)

total amount of air that can be inhaled

  • average = 4000 ml

  • calculated IC = VC - ERV

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vital capacity (VC)

total amount of air that can be exhaled

  • average = 5000 ml

  • calculated VC = TV + IRV + ERV

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residual volume (RV)

amount of air that is always left in the lungs after expiration

  • average = 1200

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total lung capacity (TLC)

total amount of air that the lungs contain, including residual volume

  • average = 6000 ml

  • calculated TLC = VC + RV

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anatomic dead space

amount of air remain in the bronchial tree that is not involved in gas exchange due to obstruction of air flow/damage to bronchial tree

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physiologic dead space

total amount of air in the lungs that is not involved in gas exchange (i.e. anatomic dead space + alveolar dead space)

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4 major factors that affect normal breathing...

  • stretching in the lungs and thoracic walls

  • O2 levels in blood

  • CO2 levels in blood

  • H+ levels in blood

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The respiratory centers is made up of the...

pons and medulla oblogata

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pulmonary capillaries

high to low (O2 enters/ CO2 enters alveoli)

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systemic capillaries

high to low (O2 enters tissues/ CO2 enters capillary)

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main factors that can shift the O2-Hb dissociation curve...

  • O2 pressure

  • CO2 pressure

  • pH of blood

  • body temp

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____ in O2 pressure shifts curve to the right.

decrease

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____ in CO2 pressure shifts curve to the right

increase

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____ shifts the curve to the right

more acidic

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increase in ___ shifts the curve to the right

body temperature

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bolus

moist lump of food particles and saliva created from mastication for easier passage into pharynx

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Name the 4 types of teeth...

  • incisors

  • canines

  • premolars

  • molars

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function of incisors

cutting

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function of incisors

tearing

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function of premolars

crushing

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function of molars

grinding

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amylase

enzyme that digests carbohydrates

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What are the 4 gastric secretory cells?

  • chief cells

  • parietal cells

  • mucous cells

  • G cells

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chief cells

secrete pepsinogen

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parietal cells

secrete HCl and intrinsic factor

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mucous cells

secrete mucus and alkaline substances to help neutralize HCl in gastric juice

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G cells

secrete gastrin which stimulates the parietal cells and overall gastric secretion

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gastrin hormone

stimulates the gastric glands for more activities

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intestinal gastrin

hormone that inhibits other gastric activities

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secretin

hormone that inhibits gastric acid secretion in response to fat in chyme

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trypsinogen

activated by enterkinase into trypsin which activates 3 other enzymes

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Name the 2 duodenal hormones that influence pancreatic secretion

  • secretin

  • cholecystokinin

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secretin

stimulates the secretion of pancreatic electrolyte - rich fluid

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cholecystokinin

  • released by intestinal wall cells

  • enhances the enzymatic secretions of the pancreas

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peritubular capillaries

same as vasa recta, found around nephron

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What are the 4 forces of filtration?

  • glomerular capillary hydrostatic pressure

  • capsular osmotic pressure

  • capsular hydrostatic pressure

  • glomerular capillary osmotic pressure

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afferent arteriole

brings blood to the glomerulus to be filtered (GFR drops when constricted)

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efferent arteriole of glomerulus

brings filtered blood out of the glomerulus (GFR will increase when constricted?)

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preritubular capillary

capillaries that surround tubule, adapted for reabsorption

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pyuria

large white blood cells (leukocytes) that are present in urine, cause by glomerulus's nephritis, UTI, or strenuous exercise

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intracellular fluid

  • 25 L of fluids (63%) are located inside body cells

  • mostly water and rich in K+, Mg++, HPO4-2, SO4-2, and protein anions

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extracellular fluid

  • 15 L of fluids (37%) are located outside of body cells

  • contains more Na+, Cl-, HCO3-, and Ca++

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Most water is absorbed in the ___

large intestines

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Most important electrolytes

Na+, Cl-, K+, Ca++, HPO42-

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Na+ (electrolyte)

most abundant extracellular cation

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Cl- (electrolyte)

major extracellular anion

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K+ (electrolyte)

most abundant cation

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Ca++

most abundant ion

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HPO42-

important intracellular anion

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chemical buffer system

acts rapidly, first line of defense against pH shift

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physiological buffer

acts slowly, second line of defense against pH shift

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respiratory acidosis

due to deficiency of CO2 expiration

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respiratory alkalosis

due to abnormally high CO2 expiration

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acid-base buffer systems

prevents rapid, drastic changes in body fluid pH

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secondary messenger

product of cascade reactions, usually cyclic adenosine monophosphate or cAMP

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nontropic hormones

hormones that are secreted by endocrine glands and travel to target cells directly

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tropic hormones

hormones that are secreted by an endocrine gland and travels to another endocrine gland, causing the second gland to secrete another hormone

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5 types of glandular cells

  • somatotrophs

  • lactotrophs

  • corticotrophs

  • thyrotrophs

  • gonadotrophs

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somatotrophs

produce GH

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lactotrophs

produce PRL

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corticotrophs

produce ACTH and MSH

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thyrotrophs

produce TSH

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gonadotrophs

produce FSH and LH

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lutheinizing hormone (LH)

triggers ovulation and stimulates the production of estrogens and progesterone in female, and promotes testosterone production in male

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growth hormone is secreted by...

anterior pituitary

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releasing hormone is from...

hypothalamus

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follicle stimulating hormone (FSH)

stimulates production of egg cells and sperm in the gonads

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placenta produces estrogen and progesterone...

after 1st trimester

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cholecytokinin (CCK)

secreted by small intestine to stimulate gallbladder activities

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corpus luteum produces estrogen and progesterone...

during 1st trimester

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parturition

means “giving birth”

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seminal vesicles

secrete an alkaline solution that makes up 60% of semen volume

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Dilation of the vagina is a ___ response in both male and female.

parasympathetic

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Orgasm in a ___ response in both male and female.

sympathetic

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corpus luteum

maintains pregnancy

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zygote

a single diploid cell

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