Liek Medication review Part 2

A patient with angina takes nitroglycerin and asks for erectile dysfunction treatment. Which medication class should never be combined with nitrates because of severe hypotension risk?

PDE-5 inhibitors

An older male with BPH reports dizziness when standing after starting a new medication. Which medication is commonly used for BPH and can cause orthostatic hypotension?

Tamsulosin

A patient starts prazosin for hypertension and faints after the first dose. Which medication class is associated with first-dose syncope?

Alpha blockers

A patient with depression wants help quitting smoking. Which medication treats both depression and smoking cessation?

Bupropion

A patient with a seizure disorder should avoid which antidepressant because it lowers seizure threshold?

Bupropion

A patient taking sertraline and tramadol develops agitation, fever, and hyperreflexia. Which antidepressant class is associated with serotonin syndrome?

SSRIs

A patient taking fluoxetine reports decreased libido and difficulty achieving orgasm. Which antidepressant class commonly causes sexual dysfunction?

SSRIs

A patient taking phenelzine eats aged cheese and develops severe hypertension and headache. Which antidepressant class can cause hypertensive crisis with tyramine foods?

MAO inhibitors

A patient taking an MAOI asks which foods to avoid. Which medication class requires avoiding aged cheese and wine?

MAO inhibitors

A patient on long-term antipsychotic therapy develops repetitive lip smacking and tongue movements. Which medication class is associated with tardive dyskinesia?

Antipsychotics

A patient taking clozapine presents with fever and sore throat. Which antipsychotic can cause agranulocytosis?

Clozapine

A psychiatric patient requires regular CBC monitoring while taking an antipsychotic. Which medication requires this due to agranulocytosis risk?

Clozapine

A patient treated for bipolar disorder develops tremors and confusion after dehydration. Which medication is associated with toxicity in this situation?

Lithium

A bipolar patient taking lithium presents with diarrhea, tremor, and confusion. What are classic signs of lithium toxicity?

Tremor, confusion, diarrhea

A patient on chronic anticoagulation requires routine INR monitoring. Which medication requires this lab test?

Warfarin

A patient taking warfarin presents with severe bleeding. Which antidote reverses the effects of warfarin?

Vitamin K

A hospitalized patient receiving heparin develops bleeding complications. Which antidote reverses heparin?

Protamine sulfate

A patient with atrial fibrillation asks for an anticoagulant that does not require regular INR checks. Which medication class is appropriate?

DOACs

A pregnant patient with a mechanical heart valve asks about anticoagulation therapy. Which medication should be avoided because of teratogenicity?

Warfarin

A patient taking seizure medication develops gum overgrowth and excessive hair growth. Which medication causes gingival hyperplasia and hirsutism?

Phenytoin

A patient recently started on a seizure medication develops a widespread blistering rash. Which medication is associated with Stevens-Johnson syndrome?

Lamotrigine

A patient taking hydralazine develops joint pain, fever, and a butterfly rash. Which medication is associated with lupus-like syndrome?

Hydralazine

A patient taking amiodarone develops progressive shortness of breath and chronic cough. Which medication can cause pulmonary fibrosis?

Amiodarone

A patient on long-term amiodarone therapy requires regular pulmonary, thyroid, and liver function tests. Which medication requires this monitoring?

Amiodarone

An older patient taking amiodarone develops blue-gray discoloration of the skin. Which medication is the likely cause?

Amiodarone

A patient on long-term prednisone develops moon face, truncal obesity, and purple striae. Which medication class can cause Cushing syndrome with prolonged use?

Corticosteroids