Salmonella GI Infections and Dz

Gram -

Faculatative anaerobes

No spores

Motile

Enterobacteria have what characteristics?

Fecal oral route

What is the method of transmission of salmonella?

Rodents and wild birds

What animals are important reservoirs of infection of Salmonella?

Stereotypes

How is salmonella enteric divided?

Mammals and birds

Salmonella typhimurium will infect?

Swine

Salmonella choleraesuis will primarily infect what?

Faculatative intracellular pathogen that survives gastric barrier and multiplies in epithelial cells causing inflammation and fluid loss and cell damage. Will be picked up by macrophages and survive there

Explain the pathogenesis of salmonella?

Spread by macrophages in the lymph and blood stream

How does salmonella get systemic?

Liver

Spleen

Brain

Meninges

Preg uterus

Joints

What tissue can extra intestinal infections of salmonella effect?

Endotoxins

Exotoxins

Biofilms

What are virulence factors of Salmonella?

Acid shock proteins

Protection in the food barrier

How does salmonella survive the gastric acid barrier?

Carrier state

Most animals will be in a ___ state when infected w/ salmonella?

Stress

-co-infection

-Transportation

-Crowding

-preg

-Temp extremes

-Anesthetics

-Antibiotics

-Diet change

What will cause sub clinically infected animals to become clinical?

Enteritis

Systemic septicemia

What are the two major forms of salmonellosis?

High economical impact

What affect does salmonella have on the cattle and poultry industry?

Cattle of all ages - enterocolitis, diarrhea, fever and likely resp illness and poss abortions

Salmonella Dublin will most commonly affect what? what are some symptoms?

Calves - enterocolitis w/ diarrhea

Salmonella typhimurium will affect what animal most often?

Zoonotic

Salmonella typhimurium is highly ____?

Septicemic dz in pigs

-hepatitis

-Pneumonia

-Cerebral vasculitis

Salmonella Choleraesuis will mostly be associated w/ what clinical signs?

Mild to moderate diarrhea

What does Salmonella typhimurium cause in pigs?

Selflimiting diarrhea to sever necrotizing enterocolitis

What does Salmonella typhimurium cause in horses?

Infectious diarrhea

Septicemia

Salminosis is a common cause of ___ in horses but ___ in neonates and foals?

Abortion, still birth, neonatal deaths

What does Salmonella Abortusovis cause in sheep?

Zoonotic

Salmonella Abortusovis can potentially be ___?

Salmonella Dublin

Salmonella Typhimurium

What other salmonella stereotypes can cause reproductive losses in Ewes?

Dogs/ cats - mild fever and enteritis

Salmonella is uncommon in what species?

Transovarian

Fecal oral

How is Salmonella Pullorum and Gallinarum contracted?

Birds under 4w old

Salmonella pullorum is most common in what animals?

White diarrhea

Anorexia

Depression

Labored breathing

High mortality

What signs will we see in Salmonella pullorum?

Growing/ adult birds

Salmonella Gallinarum (Fowl typhoid) is most common in what animals?

Anorexia

Depression

Watery to mucoid diarrhea

Septicemia w/ sudden death

What are symptoms of Salmonella Gallinarum (Fowl typhoid)?

Egg consumption

How is Salmonella typhinmurium transmitted from birds to humans?

Salmonella Typhimurium

What form of salmonella will affect reptiles and can be potentially zoonotic?

Dermatitis

Enteritis

Pneumonia

Hepatitis

Osteomyelitis

What will we see in clinical dz of Salmonella Typhimurium in reptiles?

Septicemic: IV antibiotics and supportive care

Enteric: Oral antibiotics and supportive care

How is salmonella treated?

Poultry

Cattle

Sheep

Swine

What animals have a vax for salmonella?