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designed to minimize exposure to hazardous biological materials; safety equipment, engineering controls, and PPE
Primary barrier
incorporated into the design and construction of the facility and include features such as autoclaves, specialized ventilation that provides directional airflow, air filtration, controlled access zones, or airlocks
Secondary barrier
BSL3 vs. BSL-3-Ag
BSL-3-Ag the facility barriers (secondary barriers) act as primary barriers when housing large animals that cannot be readily housed in primary containment cages
USDA Select agents
A = Anthrax
Blue = Brucella
Book = Burkholderia
Has = Hendra
No = Nipah
Real = Rift Valley
Value = Venezuelan equine encephalitis virus
What is considered final physical barrier?
PPE; should NOT be used in place of engineering controls
What are Kevlar sleeves?
prevent scratches when handling larger animals (i.e. rabbits)
discard sharps containers when _________ full
2/3-3/4
1 multiple choice option
Which entity have regulations covering waste disposal methods?
Federal level: OSHA, DOT, EPA, and FDA
removal of gross contamination
Cleaning
reduction/elimination of unacceptable concentrations of microorganisms
Disinfection
resistant to irradiation, boiling, dry heat, chemicals
Prions
Which entity regulates Nanoparticles?
NIOSH guidance
Report any significant problems/violations to IO and NIH Office of Science Policy w/in_____days
30
How many members are required on IBC?
No fewer than 5 individuals
At least 2 members not affiliated w/ institution