Antenatal Care - Biochemical Markers for Trisomy and Neural Tube Defects

Vocabulary flashcards based on lecture notes regarding biochemical marker patterns (MSAFP, hCG, unconjugated estriol, and Inhibin A) for prenatal screening of Trisomy 21, Trisomy 18, and neural tube defects.

laternal serum alpha fetal protein (MSAFP)

A marker used in prenatal screening that is Low in Trisomy 21 and 18, and High in cases of neural tube or abdominal wall defects.

$\beta$ hCG level in Trisomy 21 (Down's syndrome)

High

$\beta$ hCG level in Trisomy 18 (Edward syndrome)

Low

unconjugated estriol level in Trisomy 21 and Trisomy 18

Low in both Down's syndrome and Edward syndrome.

Inhibin A level in Trisomy 21 (Down's syndrome)

High

Inhibin A level in Trisomy 18 (Edward syndrome)

Normal/Low

Marker pattern for Neural tube defect or abdominal wall defect

High MSAFP with Normal levels of $\beta$ hCG, unconjugated estriol, and Inhibin A.

Triple Test & Quadruple Test

Antenatal screening tests (MCQ ID: MF0361 10) used alongside NIPT to detect conditions like Down's Syndrome.