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This set of flashcards summarizes essential medication information and teaching points related to endocrine, hematology, neuro/psych, and reproductive pharmacology.
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Metformin
Hold 48 hours before contrast; risk of lactic acidosis; may cause GI upset.
Sulfonylureas (Glipizide)
Can cause hypoglycemia; avoid alcohol.
Repaglinide
Must eat within 30 minutes of taking the medication.
Pioglitazone
May cause fluid retention; contraindicated in heart failure.
Acarbose
Take with the first bite; treat hypoglycemia with glucose only.
Sitagliptin
Has a risk of pancreatitis.
Insulin (Lispro)
Rapid acting; 15 min onset; give with food.
Insulin (Regular)
Only insulin that can be administered IV.
Insulin (NPH)
Cloudy appearance.
Insulin (Glargine)
No peak; cannot mix with other insulins.
GLP-1 (Ozempic, Byetta)
Can cause GI upset, weight loss, and pancreatitis.
Levothyroxine
Take in the morning on an empty stomach; lifelong therapy required.
PTU/Methimazole
Risk of agranulocytosis; report fever or sore throat.
Desmopressin
Risk of water intoxication/hyponatremia.
Steroids (Prednisone)
Can cause hyperglycemia and increased infection risk; must taper off.
Heparin
Therapeutic aPTT range: 60-80 seconds; antidote is protamine.
Warfarin
INR range: 2-3; antidote is vitamin K; avoid foods rich in vitamin K.
Dabigatran
Can cause bleeding and GI upset; store in original bottle.
Rivaroxaban/Apixaban
No monitoring required.
Aspirin/Clopidogrel
Associated with bleeding risk.
tPA
Contraindicated in active bleeding; antidote is aminocaproic acid.
Iron
Take with vitamin C; may cause black stools.
Epoetin alfa
Risk of hypertension and clots.
Filgrastim
Increases neutrophil count; may cause bone pain.
Haloperidol
Risk of extrapyramidal symptoms (EPS) and neuroleptic malignant syndrome (NMS).
Atypical Antipsychotics
Associated with weight gain and metabolic syndrome.
Stimulants (for ADHD)
Can cause weight loss, increased blood pressure, and insomnia.
Bethanechol
Used for urinary retention.
Atropine
Anticholinergic effects, leads to dryness.
Donepezil
Can cause bradycardia.
Phenytoin
Risk of gingival hyperplasia and toxicity.
Carbamazepine
Risk of agranulocytosis and syndrome of inappropriate antidiuretic hormone (SIADH).
Valproic acid
Risk of liver toxicity and pancreatitis.
Levodopa/Carbidopa
Avoid high protein meals; can cause dyskinesias.
Naloxone
Used to treat opioid overdose.
Benzodiazepines
First-line treatment for alcohol withdrawal.
Bupropion
Contraindicated in patients with seizures.
SSRIs
Can cause serotonin syndrome and sexual dysfunction.
MAOIs
Can cause hypertensive crisis when taken with tyramine-rich foods.
Lithium
Therapeutic range: 0.6–1.2; avoid NSAIDs.
Estrogen/Progestin
Increased risk of DVT; contraindicated in smokers over 35.
Plan B
Emergency contraception effective within 72 hours.
Oxytocin
Induces labor and has risk of postpartum hemorrhage.
Terbutaline
A tocolytic that may cause maternal tachycardia.
Magnesium sulfate
Toxicity includes decreased reflexes and respiratory rate <12; antidote is calcium gluconate.
Finasteride
Used for BPH; pregnant women should avoid contact.
Tamsulosin
Can cause orthostatic hypotension.
Sildenafil (ED drug)
Contraindicated with nitrates.
Emergency treatment for severe hypoglycemia
Administer IV dextrose or glucagon.
Patient teaching for levothyroxine
Must be taken on an empty stomach in the morning.
PTU patient instruction
Hold and notify provider if sore throat or fever develops.
Desmopressin risk
May lead to water intoxication or hyponatremia.
Long-term prednisone use
Increases the risk of infection.
Iron supplements instruction
Should be taken with vitamin C to enhance absorption.
Filgrastim effect
Increases neutrophils.
Haloperidol toxicity
Potential for extrapyramidal symptoms.
First sign of neuroleptic malignant syndrome
High fever and rigidity.
Bethanechol use
Indicated for urinary retention.
Atropine effects
Causes dry mouth and increased heart rate.
Donepezil risks
Can cause bradycardia.
Phenytoin monitoring
Requires monitoring for gingival hyperplasia.