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Heredity
Continuity of biological traits passed from one generation to the next through genes; offspring resemble parents because they share genes.
Variation
Inherited differences among individuals of the same species.
Genetics
The scientific study of heredity and variation.
Chromosomes
Threadlike DNA–protein structures in the nucleus containing genetic information arranged linearly.
Gene
Hereditary unit located at a specific DNA region.
Locus
Specific location of a gene on a chromosome.
Life cycle
Sequence of stages in an organism's reproductive history from conception to production of offspring.
Somatic cell
Any body cell except sperm or egg; humans have 46 chromosomes in somatic cells.
Karyotype
Photographic display of an individual's metaphase chromosomes arranged in homologous pairs.
Homologous chromosomes
Chromosome pairs with same size
Autosome
A chromosome that is not a sex chromosome.
Sex chromosome
Chromosomes that determine sex; XX in females
Diploid (2n)
Cells containing two sets of chromosomes; humans have 2n = 46.
Haploid (n)
Cells containing one set of chromosomes; gametes have n = 23 in humans.
Gamete
Haploid reproductive cell (sperm or egg).
Fertilization
Union of two gametes to form a diploid zygote.
Zygote
Diploid cell formed by fusion of two haploid gametes.
Meiosis
Cell division that produces four haploid cells from one diploid cell.
Interphase I
Phase before meiosis where chromosomes replicate and centrioles duplicate.
Prophase I
Chromosomes condense
Metaphase I
Tetrads align at metaphase plate.
Anaphase I
Homologues separate to opposite poles; sister chromatids stay attached.
Telophase I
Cytokinesis forms two haploid daughter cells; chromosomes still consist of sister chromatids.
Prophase II
Nuclear envelope breaks (if present)
Metaphase II
Chromosomes align singly on metaphase plate.
Anaphase II
Sister chromatids separate and move to opposite poles.
Telophase II
Cytokinesis forms four haploid daughter cells.
Independent assortment
Random distribution of maternal and paternal homologues during metaphase I; produces 2ⁿ combinations.
Crossing over
Exchange of genetic material between nonsister chromatids during prophase I; increases genetic variation.
Random fertilization
Random fusion of gametes; humans can produce 64 trillion possible zygote combinations.
Genetic variation importance
Provides raw material for evolution; increases survival under environmental change.
Natural selection
Process in which beneficial heritable traits increase reproductive success and become more common.
Sources of genetic variation
Sexual reproduction (independent assortment