CMM 585 Maternal Mental Health and Treatment

What percentage of women suffer from some degree of depression during pregancy?

25-35%

What are the risk of untreated depression in pregnancy?

Prematurity, low birth weight, preeclampsia, possible delays in infant cognitive and emotional development, higher rates of illicit drug use, and increase risk of postpartum depression

What are the major ways to treat depression?

Tricyclic antidepressants, Bupropion, and SSRIs

Tricyclic antidepressants and pregnancy

Most studies found no increase in malformations. Some concern about neonatal withdrawl

Bupropion and preganncy

Initial reports from manufacturer of congenital heart defects, but a goodo amount of recent data does not show an increased risk

SSRIs during pregancny

• No increased risk for birth defects

• Consistent use near term results in a small risk of a short-live neonatal adaptation syndrome (NAS)

Benzodiazepines and pregnancy

Consistent use near term is associated with “floppy infant syndrome”

Cocaine and pregnancy

Chronic use increases risk of miscarriage, placental abruption, growth restriction, vascular anomalies, and preterm delivery

Opioids and pregnancy

Have not been shown to increase birth defects and NAS if chronically used near term

Opioids and pregnancy (mother)

Abuse of narcotics has been associated with pregnancy complications such as preterm delivery and perinatal mortality