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These flashcards cover key terminology and concepts associated with the control of gene expression in bacteria.
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Gene Expression
The process by which information from a gene is used to synthesize a functional gene product, usually a protein.
Negative Control
A regulatory mechanism that suppresses gene expression; involves repressors that inhibit transcription.
Positive Control
A regulatory mechanism that promotes gene expression; involves activators that enhance transcription.
Regulon
A group of genes or operons that are regulated as a unit, often sharing a common regulatory protein.
Inducer
A molecule that initiates gene expression by disabling a repressor.
Corepressor
A molecule that binds to a repressor and increases its ability to inhibit gene expression.
Promoter
A DNA sequence where RNA polymerase binds to initiate transcription.
Constitutive Expression
Continuous expression of a gene regardless of environmental conditions.
Repressible Operon
A type of operon that is usually on and can be turned off when a specific molecule binds to a repressor.
Inducible Operon
A type of operon that is usually off and can be turned on in response to an inducer.
ToxR Regulon
A group of genes in Vibrio cholerae that are involved in producing cholera toxin and are regulated positively.
SOS Response Regulon
A regulon in E. coli involved in DNA repair processes, activated in response to DNA damage.
Catabolite Activator Protein (CAP)
A protein that enhances the transcription of genes involved in the metabolism of specific sugars.